Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ano6

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ANO6
- Mouse genes Ano6
- Rat genes Ano6
- Zfish genes ano6
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ano6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005227	calcium activated cation channel activity	ANO6	IDA		Human	PMID:22946059
Molecular Function	GO:0005227	calcium activated cation channel activity	ANO6	IMP		Human	PMID:25651887
Molecular Function	GO:0005227	calcium activated cation channel activity	Ano6	IDA		Mouse	MGI:MGI:5440105\|PMID:23021219
Molecular Function	GO:0042802	identical protein binding	Ano6	IPI	PR:Q6P9J9	Mouse	PMID:23576756
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ANO6	IMP		Human	PMID:22946059
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano6	IDA		Mouse	MGI:MGI:6316485\|PMID:30785399
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano6	IMP		Mouse	PMID:23159814
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano6	IDA		Mouse	PMID:20056604
Molecular Function	GO:0017128	phospholipid scramblase activity	ANO6	IMP		Human	PMID:30700552
Molecular Function	GO:0017128	phospholipid scramblase activity	Ano6	IDA		Mouse	MGI:MGI:6316485\|PMID:30785399
Molecular Function	GO:0017128	phospholipid scramblase activity	Ano6	IMP		Mouse	PMID:23532839
Molecular Function	GO:0017128	phospholipid scramblase activity	Ano6	IDA		Mouse	PMID:23532839
Molecular Function	GO:0005515	protein binding	ANO6	IPI	UniProtKB:P32418	Human	PMID:25589784
Molecular Function	GO:0005515	protein binding	ANO6	IPI	UniProtKB:Q99572	Human	PMID:25651887
Molecular Function	GO:0042803	protein homodimerization activity	Ano6	IDA		Mouse	MGI:MGI:6316485\|PMID:30785399
Molecular Function	GO:0005247	voltage-gated chloride channel activity	ANO6	IMP		Human	PMID:22006324
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	Ano6	IDA		Mouse	MGI:MGI:5440105\|PMID:23021219
Cellular Component	GO:0009986	cell surface	ANO6	HDA		Human	PMID:19581412
Cellular Component	GO:0034707	chloride channel complex	ANO6	IDA		Human	PMID:22006324
Cellular Component	GO:0098981	cholinergic synapse	Ano6	IDA		Mouse	PMID:32101737
Cellular Component	GO:0098981	cholinergic synapse	Ano6	IMP		Mouse	PMID:32101737
Cellular Component	GO:0005829	cytosol	ANO6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	ANO6	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ANO6	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ANO6	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ANO6	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	ANO6	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	ANO6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ANO6	IDA		Human	PMID:21107324
Cellular Component	GO:0005886	plasma membrane	ANO6	IDA		Human	PMID:22946059
Cellular Component	GO:0005886	plasma membrane	ANO6	IDA		Human	PMID:25651887
Cellular Component	GO:0005886	plasma membrane	Ano6	IDA		Mouse	MGI:MGI:6316485\|PMID:30785399
Cellular Component	GO:0097060	synaptic membrane	Ano6	IDA		Mouse	PMID:32101737
Biological Process	GO:0002543	activation of blood coagulation via clotting cascade	ANO6	IMP		Human	PMID:21107324
Biological Process	GO:0032060	bleb assembly	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0032060	bleb assembly	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:0007596	blood coagulation	Ano6	IMP		Mouse	MGI:MGI:5440105\|PMID:23021219
Biological Process	GO:0035630	bone mineralization involved in bone maturation	Ano6	IMP	MGI:MGI:4127698	Mouse	PMID:22936354
Biological Process	GO:0061591	calcium activated galactosylceramide scrambling	Ano6	IDA		Mouse	PMID:23532839
Biological Process	GO:0061590	calcium activated phosphatidylcholine scrambling	Ano6	IDA		Mouse	PMID:23532839
Biological Process	GO:0061589	calcium activated phosphatidylserine scrambling	Ano6	IDA		Mouse	PMID:23532839
Biological Process	GO:0061588	calcium activated phospholipid scrambling	Ano6	IMP		Mouse	PMID:23532839
Biological Process	GO:0061588	calcium activated phospholipid scrambling	Ano6	IMP	MGI:MGI:4127698	Mouse	PMID:22936354
Biological Process	GO:0070588	calcium ion transmembrane transport	ANO6	IGI	UniProtKB:P32418	Human	PMID:25589784
Biological Process	GO:0070588	calcium ion transmembrane transport	Ano6	IGI	UniProtKB:P70414	Mouse	MGI:MGI:5634871\|PMID:25589784
Biological Process	GO:1902476	chloride transmembrane transport	ANO6	IGI	UniProtKB:P32418	Human	PMID:25589784
Biological Process	GO:1902476	chloride transmembrane transport	Ano6	IDA		Mouse	MGI:MGI:6316485\|PMID:30785399
Biological Process	GO:1902476	chloride transmembrane transport	Ano6	IMP		Mouse	MGI:MGI:5634871\|PMID:25589784
Biological Process	GO:0006821	chloride transport	ANO6	IMP		Human	PMID:22006324
Biological Process	GO:0006821	chloride transport	ANO6	IMP		Human	PMID:22946059
Biological Process	GO:0006821	chloride transport	Ano6	IDA		Mouse	PMID:20056604
Biological Process	GO:0006821	chloride transport	Ano6	IMP		Mouse	PMID:23159814
Biological Process	GO:0002407	dendritic cell chemotaxis	Ano6	IMP		Mouse	PMID:23159814
Biological Process	GO:0051649	establishment of localization in cell	Ano6	IMP	MGI:MGI:4127698	Mouse	PMID:22936354
Biological Process	GO:0051649	establishment of localization in cell	Ano6	IDA		Mouse	PMID:23532839
Biological Process	GO:0051649	establishment of localization in cell	Ano6	IMP		Mouse	PMID:23532839
Biological Process	GO:0051649	establishment of localization in cell	Ano6	IMP		Mouse	PMID:23159814
Biological Process	GO:0006812	monoatomic cation transport	ANO6	IDA		Human	PMID:22946059
Biological Process	GO:0045794	negative regulation of cell volume	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0045794	negative regulation of cell volume	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:0097045	phosphatidylserine exposure on blood platelet	ANO6	IMP		Human	PMID:21107324
Biological Process	GO:0045332	phospholipid translocation	Ano6	IDA		Mouse	MGI:MGI:6316485\|PMID:30785399
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	ANO6	IMP		Human	PMID:30700552
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	Ano6	IMP		Mouse	MGI:MGI:5440105\|PMID:23021219
Biological Process	GO:0046931	pore complex assembly	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0043065	positive regulation of apoptotic process	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:0030501	positive regulation of bone mineralization	ANO6	IMP		Human	PMID:25589784
Biological Process	GO:0030501	positive regulation of bone mineralization	Ano6	IMP		Mouse	MGI:MGI:5634871\|PMID:25589784
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	ANO6	IMP		Human	PMID:22006324
Biological Process	GO:0034767	positive regulation of monoatomic ion transmembrane transport	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0034767	positive regulation of monoatomic ion transmembrane transport	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:1903766	positive regulation of potassium ion export across plasma membrane	Ano6	IMP		Rat	PMID:23872594\|RGD:9681745
Biological Process	GO:0035590	purinergic nucleotide receptor signaling pathway	ANO6	IMP		Human	PMID:25651887
Biological Process	GO:0035590	purinergic nucleotide receptor signaling pathway	Ano6	IMP		Mouse	MGI:MGI:5634870\|PMID:25651887
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Ano6	IDA		Mouse	PMID:32101737
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Ano6	IMP		Mouse	PMID:32101737
Biological Process	GO:0035725	sodium ion transmembrane transport	ANO6	IGI	UniProtKB:P32418	Human	PMID:25589784
Biological Process	GO:0002040	sprouting angiogenesis	ano6	IMP	ZFIN:ZDB-MRPHLNO-150302-2	Zfish	PMID:25384978
Biological Process	GO:0002040	sprouting angiogenesis	ano6	IMP	ZFIN:ZDB-MRPHLNO-150302-10	Zfish	PMID:25384978

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/03/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.