Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANPEP
  • Mouse genes Anpep
  • Rat genes Anpep
  • Zfish genes anpepa,anpepb.1,anpepla,anpeplb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Anpep

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004177	aminopeptidase activity	Anpep	IDA		Rat	PMID:16537183|RGD:1581649
Molecular Function	GO:0004177	aminopeptidase activity	Anpep	IDA		Rat	PMID:16619500|RGD:1582109
Molecular Function	GO:0042277	peptide binding	Anpep	IDA		Rat	PMID:16537183|RGD:1581649
Molecular Function	GO:0042277	peptide binding	Anpep	IDA		Rat	PMID:8702598|RGD:1625498
Cellular Component	GO:0031526	brush border membrane	Anpep	IDA		Rat	PMID:12110004|RGD:1626500
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ANPEP	IDA		Human	PMID:15308636
Cellular Component	GO:0009897	external side of plasma membrane	Anpep	IDA		Mouse	PMID:21708977
Cellular Component	GO:0070062	extracellular exosome	ANPEP	IDA		Human	PMID:15326289
Cellular Component	GO:0070062	extracellular exosome	ANPEP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ANPEP	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ANPEP	IDA		Human	PMID:21082674
Cellular Component	GO:0070062	extracellular exosome	ANPEP	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	ANPEP	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	ANPEP	IDA		Human	PMID:25645918
Cellular Component	GO:0005765	lysosomal membrane	ANPEP	HDA		Human	PMID:17897319
Cellular Component	GO:0005886	plasma membrane	ANPEP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ANPEP	IDA		Human	PMID:2564851
Biological Process	GO:0072237	metanephric proximal tubule development	Anpep	IEP		Rat	PMID:30645697|RGD:155631307
Biological Process	GO:0035814	negative regulation of renal sodium excretion	Anpep	IMP		Rat	PMID:19996063|RGD:5131447
Biological Process	GO:0043171	peptide catabolic process	Anpep	IMP		Rat	PMID:12110004|RGD:1626500
Biological Process	GO:0016485	protein processing	Anpep	IDA		Rat	PMID:16537183|RGD:1581649

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern