Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Anxa1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ANXA1
- Mouse genes Anxa1
- Rat genes Anxa1
- Zfish genes anxa1a,anxa1b,anxa1c,anxa1d
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Anxa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098641	cadherin binding involved in cell-cell adhesion	ANXA1	HDA		Human	PMID:25468996
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ANXA1	IDA		Human	PMID:2138016
Molecular Function	GO:0048306	calcium-dependent protein binding	ANXA1	IPI	UniProtKB:P01023	Human	PMID:15226301
Molecular Function	GO:1990814	DNA/DNA annealing activity	Anxa1	IDA		Rat	PMID:20655937\|RGD:7421590
Molecular Function	GO:0036121	double-stranded DNA helicase activity	Anxa1	IDA		Rat	PMID:20655937\|RGD:7421590
Molecular Function	GO:0042802	identical protein binding	Anxa1	IPI	RGD:2118	Rat	PMID:20655937\|RGD:7421590
Molecular Function	GO:0042802	identical protein binding	Anxa1	IPI	RGD:2118	Rat	PMID:8335093\|RGD:2306960
Molecular Function	GO:0008289	lipid binding	ANXA1	EXP		Human	PMID:8756690
Molecular Function	GO:0019834	phospholipase A2 inhibitor activity	ANXA1	IDA		Human	PMID:2936963
Molecular Function	GO:0019834	phospholipase A2 inhibitor activity	ANXA1	IDA		Human	PMID:3013422
Molecular Function	GO:0019834	phospholipase A2 inhibitor activity	Anxa1	IDA		Rat	PMID:10806526\|RGD:2306913
Molecular Function	GO:0019834	phospholipase A2 inhibitor activity	Anxa1	IDA		Rat	PMID:2969352\|RGD:7421659
Molecular Function	GO:0005543	phospholipid binding	Anxa1	IDA		Rat	PMID:17993484\|RGD:2306890
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:Q13546	Human	PMID:21383699
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:Q9Y6K9	Human	PMID:21383699
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:Q9C0E8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:Q6P5S2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:Q96EF9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:Q9NVM1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:A0A0F6AZQ1	Human	PMID:34237247
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:A0A0F6B1Q8	Human	PMID:34237247
Molecular Function	GO:0005515	protein binding	ANXA1	IPI	UniProtKB:A0A0F6B5H5	Human	PMID:34237247
Molecular Function	GO:0005515	protein binding	Anxa1	IPI	UniProtKB:A0A0F6B5H5	Mouse	MGI:MGI:6810806\|PMID:34237247
Molecular Function	GO:0005515	protein binding	Anxa1	IPI	PR:Q9ESD7	Mouse	PMID:14506282
Molecular Function	GO:0005515	protein binding	Anxa1	IPI	PR:Q9ESD7	Mouse	PMID:20405035
Molecular Function	GO:0003697	single-stranded DNA binding	Anxa1	IDA		Rat	PMID:10548514\|RGD:2306916
Molecular Function	GO:0003697	single-stranded DNA binding	Anxa1	IDA		Rat	PMID:20655937\|RGD:7421590
Molecular Function	GO:0003727	single-stranded RNA binding	Anxa1	IDA		Rat	PMID:10548514\|RGD:2306916
Cellular Component	GO:0005884	actin filament	ANXA1	IDA		Human	PMID:22773844
Cellular Component	GO:0005912	adherens junction	ANXA1	HDA		Human	PMID:25468996
Cellular Component	GO:0016324	apical plasma membrane	Anxa1	IDA		Mouse	MGI:MGI:3760064\|PMID:17384087
Cellular Component	GO:0016324	apical plasma membrane	Anxa1	IDA		Mouse	MGI:MGI:3822074\|PMID:18802107
Cellular Component	GO:0009986	cell surface	ANXA1	IDA		Human	PMID:22056994
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA1	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa1	HDA		Mouse	MGI:MGI:6201853\|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa1	HDA		Mouse	MGI:MGI:6201834\|PMID:22159717
Cellular Component	GO:0001533	cornified envelope	ANXA1	IDA		Human	PMID:10908733
Cellular Component	GO:0001533	cornified envelope	Anxa1	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005737	cytoplasm	ANXA1	IDA		Human	PMID:10772777
Cellular Component	GO:0005737	cytoplasm	ANXA1	IDA		Human	PMID:17008549
Cellular Component	GO:0005737	cytoplasm	ANXA1	IDA		Human	PMID:19625660
Cellular Component	GO:0005737	cytoplasm	ANXA1	IDA		Human	PMID:22056994
Cellular Component	GO:0005737	cytoplasm	Anxa1	IDA		Mouse	MGI:MGI:3822074\|PMID:18802107
Cellular Component	GO:0005737	cytoplasm	Anxa1	IDA		Rat	PMID:17994624\|RGD:2306889
Cellular Component	GO:0005829	cytosol	ANXA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005768	endosome	ANXA1	IDA		Human	PMID:18767904
Cellular Component	GO:0070062	extracellular exosome	ANXA1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ANXA1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ANXA1	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	ANXA1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	ANXA1	IDA		Human	PMID:25664854
Cellular Component	GO:0005615	extracellular space	ANXA1	IDA		Human	PMID:17008549
Cellular Component	GO:0005615	extracellular space	ANXA1	IDA		Human	PMID:19625660
Cellular Component	GO:0005615	extracellular space	ANXA1	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	ANXA1	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	ANXA1	IDA		Human	PMID:25664854
Cellular Component	GO:0005615	extracellular space	Anxa1	IDA		Rat	PMID:10489933\|RGD:2306920
Cellular Component	GO:0031232	extrinsic component of external side of plasma membrane	ANXA1	IDA		Human	PMID:19625660
Cellular Component	GO:0019898	extrinsic component of membrane	ANXA1	IDA		Human	PMID:17008549
Cellular Component	GO:0005925	focal adhesion	ANXA1	HDA		Human	PMID:21423176
Cellular Component	GO:0016328	lateral plasma membrane	Anxa1	IDA		Mouse	MGI:MGI:3822074\|PMID:18802107
Cellular Component	GO:0042629	mast cell granule	Anxa1	IDA		Rat	PMID:11005211\|RGD:7421660
Cellular Component	GO:0031966	mitochondrial membrane	Anxa1	IDA		Rat	PMID:10806526\|RGD:2306913
Cellular Component	GO:0031514	motile cilium	Anxa1	IDA		Mouse	MGI:MGI:3760064\|PMID:17384087
Cellular Component	GO:0005654	nucleoplasm	ANXA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ANXA1	IDA		Human	PMID:10772777
Cellular Component	GO:0005634	nucleus	ANXA1	IDA		Human	PMID:22056994
Cellular Component	GO:0005634	nucleus	Anxa1	IDA		Rat	PMID:17994624\|RGD:2306889
Cellular Component	GO:0005886	plasma membrane	ANXA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ANXA1	IDA		Human	PMID:10772777
Cellular Component	GO:0005886	plasma membrane	Anxa1	IMP		Mouse	MGI:MGI:3830429\|PMID:19095957
Cellular Component	GO:0005886	plasma membrane	Anxa1	IDA		Rat	PMID:12467520\|RGD:2306908
Cellular Component	GO:0032991	protein-containing complex	Anxa1	IDA		Rat	PMID:10548514\|RGD:2306916
Cellular Component	GO:0042383	sarcolemma	Anxa1	IDA		Mouse	PMID:14506282
Cellular Component	GO:0097060	synaptic membrane	Anxa1	IDA		Rat	PMID:8335093\|RGD:2306960
Cellular Component	GO:0031982	vesicle	ANXA1	HDA		Human	PMID:19190083
Biological Process	GO:0031532	actin cytoskeleton reorganization	ANXA1	IDA		Human	PMID:15187149
Biological Process	GO:0046632	alpha-beta T cell differentiation	Anxa1	IMP		Mouse	MGI:MGI:4943619\|PMID:20139728
Biological Process	GO:0050482	arachidonic acid secretion	Anxa1	IMP	MGI:MGI:2449710	Mouse	PMID:12553880
Biological Process	GO:0007166	cell surface receptor signaling pathway	Anxa1	IDA		Rat	PMID:12459455\|RGD:628365
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	ANXA1	IDA		Human	PMID:2936963
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Anxa1	IMP		Mouse	MGI:MGI:2449418\|PMID:12475898
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Anxa1	IDA		Rat	PMID:2936963\|RGD:8553594
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Anxa1	IMP		Rat	PMID:8607818\|RGD:2306955
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	ANXA1	IDA		Human	PMID:22773844
Biological Process	GO:0032508	DNA duplex unwinding	Anxa1	IDA		Rat	PMID:20655937\|RGD:7421590
Biological Process	GO:0031018	endocrine pancreas development	Anxa1	IEP		Rat	PMID:7527053\|RGD:2306957
Biological Process	GO:0044849	estrous cycle	Anxa1	IEP		Rat	PMID:17283243\|RGD:2306897
Biological Process	GO:0031101	fin regeneration	anxa1a	IEP		Zfish	PMID:22278371
Biological Process	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	ANXA1	IMP		Human	PMID:15187149
Biological Process	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	ANXA1	IDA		Human	PMID:25664854
Biological Process	GO:0042063	gliogenesis	Anxa1	IEP		Rat	PMID:9263577\|RGD:2306949
Biological Process	GO:0071621	granulocyte chemotaxis	ANXA1	IDA		Human	PMID:15187149
Biological Process	GO:0070365	hepatocyte differentiation	Anxa1	IEP		Rat	PMID:11668598\|RGD:2306909
Biological Process	GO:0006954	inflammatory response	Anxa1	IMP		Mouse	MGI:MGI:3822074\|PMID:18802107
Biological Process	GO:0030073	insulin secretion	Anxa1	IDA		Rat	PMID:12459455\|RGD:628365
Biological Process	GO:0030216	keratinocyte differentiation	ANXA1	IDA		Human	PMID:10908733
Biological Process	GO:0051179	localization	ANXA1	EXP		Human	PMID:8756690
Biological Process	GO:0002548	monocyte chemotaxis	ANXA1	IDA		Human	PMID:15187149
Biological Process	GO:0014839	myoblast migration involved in skeletal muscle regeneration	Anxa1	IDA		Mouse	MGI:MGI:5619736\|PMID:23144744
Biological Process	GO:0045920	negative regulation of exocytosis	ANXA1	IMP		Human	PMID:19625660
Biological Process	GO:0032717	negative regulation of interleukin-8 production	ANXA1	IMP		Human	PMID:22056994
Biological Process	GO:1900138	negative regulation of phospholipase A2 activity	Anxa1	IDA		Rat	PMID:2969352\|RGD:7421659
Biological Process	GO:0050709	negative regulation of protein secretion	Anxa1	IMP		Rat	PMID:8559285\|RGD:2306956
Biological Process	GO:0045629	negative regulation of T-helper 2 cell differentiation	ANXA1	IDA		Human	PMID:17008549
Biological Process	GO:0042119	neutrophil activation	ANXA1	IDA		Human	PMID:22879591
Biological Process	GO:0097350	neutrophil clearance	ANXA1	IMP		Human	PMID:21957127
Biological Process	GO:0001780	neutrophil homeostasis	ANXA1	IMP		Human	PMID:21957127
Biological Process	GO:0001780	neutrophil homeostasis	Anxa1	IMP		Mouse	MGI:MGI:5304979\|PMID:21957127
Biological Process	GO:0018149	peptide cross-linking	ANXA1	IDA		Human	PMID:10908733
Biological Process	GO:0006909	phagocytosis	Anxa1	IMP		Mouse	MGI:MGI:2449418\|PMID:12475898
Biological Process	GO:0043065	positive regulation of apoptotic process	Anxa1	IMP		Rat	PMID:8607818\|RGD:2306955
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	ANXA1	IDA		Human	PMID:22773844
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	Anxa1	IMP	MGI:MGI:2449710	Mouse	PMID:12553880
Biological Process	GO:0032743	positive regulation of interleukin-2 production	ANXA1	IDA		Human	PMID:17008549
Biological Process	GO:0033031	positive regulation of neutrophil apoptotic process	Anxa1	IMP		Mouse	MGI:MGI:5304979\|PMID:21957127
Biological Process	GO:0031394	positive regulation of prostaglandin biosynthetic process	Anxa1	IMP		Rat	PMID:8260938\|RGD:2306959
Biological Process	GO:0042102	positive regulation of T cell proliferation	ANXA1	IDA		Human	PMID:17008549
Biological Process	GO:0045627	positive regulation of T-helper 1 cell differentiation	ANXA1	IDA		Human	PMID:17008549
Biological Process	GO:0031340	positive regulation of vesicle fusion	ANXA1	IDA		Human	PMID:2138016
Biological Process	GO:0090303	positive regulation of wound healing	ANXA1	IDA		Human	PMID:25664854
Biological Process	GO:0070459	prolactin secretion	Anxa1	IMP		Rat	PMID:10830310\|RGD:7421661
Biological Process	GO:0030850	prostate gland development	Anxa1	IEP		Rat	PMID:22911278\|RGD:7421658
Biological Process	GO:0042127	regulation of cell population proliferation	Anxa1	IMP	MGI:MGI:2449710	Mouse	PMID:12553880
Biological Process	GO:0008360	regulation of cell shape	ANXA1	IDA		Human	PMID:15187149
Biological Process	GO:0046883	regulation of hormone secretion	ANXA1	IMP		Human	PMID:19625660
Biological Process	GO:0050727	regulation of inflammatory response	Anxa1	IMP		Mouse	MGI:MGI:2449418\|PMID:12475898
Biological Process	GO:0032652	regulation of interleukin-1 production	Anxa1	IMP		Mouse	MGI:MGI:2449418\|PMID:12475898
Biological Process	GO:0002685	regulation of leukocyte migration	Anxa1	IMP		Mouse	MGI:MGI:2449418\|PMID:12475898
Biological Process	GO:0031960	response to corticosteroid	Anxa1	IEP		Rat	PMID:9416328\|RGD:2306951
Biological Process	GO:0032355	response to estradiol	Anxa1	IEP		Rat	PMID:17283243\|RGD:2306897
Biological Process	GO:0051384	response to glucocorticoid	Anxa1	IEP		Rat	PMID:17283243\|RGD:2306897
Biological Process	GO:0009725	response to hormone	Anxa1	IEP		Rat	PMID:9022675\|RGD:2306952
Biological Process	GO:0070555	response to interleukin-1	Anxa1	IEP		Rat	PMID:11311405\|RGD:2306911
Biological Process	GO:0014070	response to organic cyclic compound	Anxa1	IEP		Rat	PMID:8300854\|RGD:2306958
Biological Process	GO:0043434	response to peptide hormone	Anxa1	IEP		Rat	PMID:8828496\|RGD:2306953
Biological Process	GO:0010165	response to X-ray	Anxa1	IEP		Rat	PMID:9269316\|RGD:2306948
Biological Process	GO:0009410	response to xenobiotic stimulus	Anxa1	IEP		Rat	PMID:9416328\|RGD:2306951
Biological Process	GO:0051238	sequestering of metal ion	ANXA1	EXP		Human	PMID:11078886
Biological Process	GO:0007165	signal transduction	Anxa1	IMP	MGI:MGI:2449710	Mouse	PMID:12553880

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.