Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANXA4
  • Mouse genes Anxa4
  • Rat genes Anxa4
  • Zfish genes anxa4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Anxa4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	ANXA4	IDA		Human	PMID:20237821
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ANXA4	IDA		Human	PMID:2138016
Molecular Function	GO:0048306	calcium-dependent protein binding	ANXA4	IPI	UniProtKB:P01023	Human	PMID:15226301
Molecular Function	GO:0048306	calcium-dependent protein binding	ANXA4	IPI	UniProtKB:P19838	Human	PMID:20237821
Molecular Function	GO:0042802	identical protein binding	ANXA4	IPI	UniProtKB:P09525	Human	PMID:16687573
Molecular Function	GO:0051059	NF-kappaB binding	ANXA4	IPI	UniProtKB:P19838	Human	PMID:20237821
Molecular Function	GO:0051059	NF-kappaB binding	ANXA4	IPI	UniProtKB:P19838:PRO_0000030311	Human	PMID:20237821
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:Q9UM07	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:Q9UM07	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:O75190-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:P02511	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:P49591	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:P62826	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA4	IPI	UniProtKB:Q0VDC6	Human	PMID:32814053
Cellular Component	GO:0009986	cell surface	ANXA4	IDA		Human	PMID:22056994
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA4	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA4	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa4	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	ANXA4	IDA		Human	PMID:20237821
Cellular Component	GO:0070062	extracellular exosome	ANXA4	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ANXA4	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ANXA4	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ANXA4	HDA		Human	PMID:23533145
Cellular Component	GO:0031965	nuclear membrane	ANXA4	IDA		Human	PMID:16687573
Cellular Component	GO:0005634	nucleus	ANXA4	IDA		Human	PMID:16687573
Cellular Component	GO:0005634	nucleus	ANXA4	IDA		Human	PMID:20237821
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ANXA4	IDA		Human	PMID:16687573
Cellular Component	GO:0005886	plasma membrane	ANXA4	IDA		Human	PMID:16687573
Cellular Component	GO:0012506	vesicle membrane	ANXA4	IDA		Human	PMID:16687573
Biological Process	GO:0030855	epithelial cell differentiation	ANXA4	IEP		Human	PMID:21492153
Biological Process	GO:0032717	negative regulation of interleukin-8 production	ANXA4	IMP		Human	PMID:22056994
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ANXA4	IDA		Human	PMID:20237821
Biological Process	GO:0007219	Notch signaling pathway	Anxa4	IDA		Mouse	PMID:25446530
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ANXA4	IDA		Human	PMID:20237821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern