Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANXA5
  • Mouse genes Anxa5
  • Rat genes Anxa5
  • Zfish genes anxa5a,anxa5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Anxa5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ANXA5	IDA		Human	PMID:2138016
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Anxa5	IDA		Rat	PMID:12401794|RGD:634648
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Anxa5	IMP		Rat	PMID:12401794|RGD:634648
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Anxa5	IDA		Rat	PMID:2307675|RGD:2317539
Molecular Function	GO:0042802	identical protein binding	Anxa5	IPI	RGD:2120	Rat	PMID:12401794|RGD:634648
Molecular Function	GO:0005388	P-type calcium transporter activity	Anxa5	IDA		Rat	PMID:9299392|RGD:10053703
Molecular Function	GO:0017046	peptide hormone binding	Anxa5	IDA		Rat	PMID:1386737|RGD:7241860
Molecular Function	GO:0001786	phosphatidylserine binding	Anxa5	IDA		Mouse	PMID:12000961
Molecular Function	GO:0005515	protein binding	ANXA5	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ANXA5	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ANXA5	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA5	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ANXA5	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Anxa5	IPI	UniProtKB:Q08460	Mouse	MGI:MGI:3852248|PMID:19423573
Molecular Function	GO:0005515	protein binding	Anxa5	IPI	UniProtKB:Q6TEM9	Mouse	MGI:MGI:3836137|PMID:14651927
Molecular Function	GO:0005515	protein binding	Anxa5	IPI	RGD:735017	Rat	PMID:8667030|RGD:631943
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Anxa5	IPI	RGD:2965	Rat	PMID:10329451|RGD:2292112
Cellular Component	GO:0043679	axon terminus	Anxa5	IDA		Rat	PMID:8931014|RGD:10053658
Cellular Component	GO:0042995	cell projection	Anxa5	IDA		Rat	PMID:1833446|RGD:2317540
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA5	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA5	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa5	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa5	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	Anxa5	IDA		Rat	PMID:1833446|RGD:2317540
Cellular Component	GO:0005737	cytoplasm	anxa5b	IDA		Zfish	PMID:14651927
Cellular Component	GO:0005829	cytosol	Anxa5	IDA		Rat	PMID:2151331|RGD:10053689
Cellular Component	GO:0030425	dendrite	Anxa5	IDA		Rat	PMID:8931014|RGD:10053658
Cellular Component	GO:0005783	endoplasmic reticulum	Anxa5	IDA		Rat	PMID:8725344|RGD:2316073
Cellular Component	GO:0072563	endothelial microparticle	Anxa5	IDA		Mouse	MGI:MGI:4850200|PMID:20978343
Cellular Component	GO:0009897	external side of plasma membrane	Anxa5	IDA		Mouse	PMID:17082577
Cellular Component	GO:0009897	external side of plasma membrane	Anxa5	IDA		Mouse	PMID:21508411
Cellular Component	GO:0009897	external side of plasma membrane	Anxa5	IDA		Mouse	PMID:19934022
Cellular Component	GO:0009897	external side of plasma membrane	Anxa5	IDA		Mouse	PMID:19623612
Cellular Component	GO:0070062	extracellular exosome	ANXA5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ANXA5	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ANXA5	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	ANXA5	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Anxa5	IDA		Rat	PMID:11271515|RGD:7241853
Cellular Component	GO:0005925	focal adhesion	ANXA5	HDA		Human	PMID:21423176
Cellular Component	GO:0014704	intercalated disc	Anxa5	IDA		Rat	PMID:1833446|RGD:2317540
Cellular Component	GO:0016020	membrane	ANXA5	HDA		Human	PMID:19946888
Cellular Component	GO:0043025	neuronal cell body	Anxa5	IDA		Rat	PMID:8725344|RGD:2316073
Cellular Component	GO:0005634	nucleus	Anxa5	IDA		Rat	PMID:9723888|RGD:7241856
Cellular Component	GO:0043204	perikaryon	Anxa5	IDA		Rat	PMID:8931014|RGD:10053658
Cellular Component	GO:0005886	plasma membrane	Anxa5	IDA		Rat	PMID:1833446|RGD:2317540
Cellular Component	GO:0042383	sarcolemma	Anxa5	IDA		Rat	PMID:1833446|RGD:2317540
Cellular Component	GO:0008021	synaptic vesicle	Anxa5	IDA		Rat	PMID:8931014|RGD:10053658
Cellular Component	GO:0030672	synaptic vesicle membrane	Anxa5	IDA		Rat	PMID:8931014|RGD:10053658
Cellular Component	GO:0030018	Z disc	Anxa5	IDA		Rat	PMID:7585827|RGD:7241857
Biological Process	GO:0097211	cellular response to gonadotropin-releasing hormone	Anxa5	IMP		Rat	PMID:18504344|RGD:10053655
Biological Process	GO:0071284	cellular response to lead ion	Anxa5	IEP		Rat	PMID:11578147|RGD:10053705
Biological Process	GO:0030195	negative regulation of blood coagulation	Anxa5	IDA		Rat	PMID:20684318|RGD:7241850
Biological Process	GO:1902721	negative regulation of prolactin secretion	Anxa5	IMP		Rat	PMID:15256781|RGD:10053690
Biological Process	GO:0043065	positive regulation of apoptotic process	Anxa5	IDA		Rat	PMID:15537503|RGD:2317544
Biological Process	GO:2000145	regulation of cell motility	anxa5b	IGI	ZFIN:ZDB-MRPHLNO-050413-1,ZFIN:ZDB-MRPHLNO-120823-1,ZFIN:ZDB-MRPHLNO-120823-2,ZFIN:ZDB-MRPHLNO-120823-3,ZFIN:ZDB-MRPHLNO-120823-4,ZFIN:ZDB-MRPHLNO-120823-5	Zfish	PMID:22705393
Biological Process	GO:1901317	regulation of flagellated sperm motility	Anxa5	IDA		Rat	PMID:20684318|RGD:7241850
Biological Process	GO:0051592	response to calcium ion	Anxa5	IDA		Rat	PMID:8362244|RGD:7241859
Biological Process	GO:0010033	response to organic substance	Anxa5	IDA		Mouse	PMID:16455971
Biological Process	GO:0097066	response to thyroid hormone	Anxa5	IEP		Rat	PMID:9022675|RGD:2306952

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern