Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANXA6
  • Mouse genes Anxa6
  • Rat genes Anxa6
  • Zfish genes anxa6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Anxa6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ANXA6	IDA		Human	PMID:2138016
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Anxa6	IDA		Rat	PMID:12105190|RGD:724802
Molecular Function	GO:0048306	calcium-dependent protein binding	ANXA6	IPI	UniProtKB:P01023	Human	PMID:15226301
Molecular Function	GO:0015485	cholesterol binding	ANXA6	IDA		Human	PMID:23360953
Molecular Function	GO:0005525	GTP binding	ANXA6	IMP		Human	PMID:16605264
Molecular Function	GO:0042802	identical protein binding	ANXA6	IPI	UniProtKB:P08133	Human	PMID:16605264
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	ANXA6	IMP		Human	PMID:16605264
Molecular Function	GO:0008289	lipid binding	ANXA6	IMP		Human	PMID:16605264
Molecular Function	GO:0005515	protein binding	ANXA6	IPI	UniProtKB:P55327	Human	PMID:15576473
Molecular Function	GO:0005515	protein binding	ANXA6	IPI	UniProtKB:P10636-8	Human	PMID:29636414
Molecular Function	GO:0005515	protein binding	ANXA6	IPI	UniProtKB:Q14005-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Anxa6	IPI	RGD:3537	Rat	PMID:10708762|RGD:1642649
Molecular Function	GO:0044877	protein-containing complex binding	Anxa6	IPI	RGD:628758|RGD:3537	Rat	PMID:10708762|RGD:1642649
Cellular Component	GO:0016324	apical plasma membrane	Anxa6	IDA		Rat	PMID:12105190|RGD:724802
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA6	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA6	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA6	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ANXA6	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa6	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Anxa6	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	Anxa6	IDA		Rat	PMID:12105190|RGD:724802
Cellular Component	GO:0070062	extracellular exosome	ANXA6	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ANXA6	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ANXA6	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	ANXA6	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	ANXA6	HDA		Human	PMID:21423176
Cellular Component	GO:0014704	intercalated disc	Anxa6	IDA		Rat	PMID:8252600|RGD:10053657
Cellular Component	GO:0031902	late endosome membrane	ANXA6	IDA		Human	PMID:23360953
Cellular Component	GO:0005765	lysosomal membrane	ANXA6	IDA		Human	PMID:23360953
Cellular Component	GO:0016020	membrane	ANXA6	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Anxa6	IDA		Rat	PMID:23525114|RGD:12911212
Cellular Component	GO:0005634	nucleus	Anxa6	IDA		Rat	PMID:8252600|RGD:10053657
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Anxa6	IDA		Mouse	PMID:15078881
Cellular Component	GO:0032991	protein-containing complex	Anxa6	IDA		Rat	PMID:15823548|RGD:1600561
Cellular Component	GO:0042383	sarcolemma	Anxa6	IDA		Rat	PMID:8252600|RGD:10053657
Biological Process	GO:0097190	apoptotic signaling pathway	Anxa6	IMP		Mouse	MGI:MGI:5485084|PMID:23341998
Biological Process	GO:0006816	calcium ion transport	Anxa6	IMP		Mouse	PMID:11919174
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	Anxa6	IMP		Mouse	MGI:MGI:5485084|PMID:23341998
Biological Process	GO:0034220	monoatomic ion transmembrane transport	ANXA6	IMP		Human	PMID:16605264
Biological Process	GO:0001778	plasma membrane repair	anxa6	IMP	ZFIN:ZDB-MRPHLNO-120404-3	Zfish	PMID:22421042
Biological Process	GO:0006937	regulation of muscle contraction	Anxa6	IMP		Mouse	PMID:11919174

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern