Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ap2m1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes AP2M1
- Mouse genes Ap2m1
- Rat genes Ap2m1
- Zfish genes ap2m1a,ap2m1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ap2m1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097718	disordered domain specific binding	Ap2m1	IDA		Mouse	MGI:MGI:5882886\|PMID:18321067
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	Ap2m1	IDA		Rat	PMID:12121421\|RGD:10047190
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9UI12	Human	PMID:12032142
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P63010	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q92609	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9UHP6	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q5VV43	Human	PMID:19419997
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P51114	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P27958:PRO_0000037566	Human	PMID:22916011
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:O14672,UniProtKB:O94973,UniProtKB:O95782,UniProtKB:P63010	Human	PMID:23676497
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P63010	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q7Z3C6	Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q92609	Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P63010	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q92609	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P0DPH9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P35268	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P55081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P62807	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q00013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q03393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q16778	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q1ED39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q68CQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q6ZUT1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q8N3F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q8N8X9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q8N9N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q8NAV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q96EY4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q96JC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q96MH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q99633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q99880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9BSU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9BU76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9NZ81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9P0T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9UHP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q7Z3C6	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q9BYF1	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:Q7Z3C6	Human	PMID:34799561
Molecular Function	GO:0005515	protein binding	AP2M1	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:O35598,UniProtKB:P17426,UniProtKB:P17427,UniProtKB:Q9DBG3	Mouse	MGI:MGI:5514106\|PMID:23676497
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P32004	Mouse	MGI:MGI:5882886\|PMID:18321067
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P18484,UniProtKB:P62743,UniProtKB:P63010	Rat	PMID:12086608\|RGD:12793054
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	RGD:61811	Rat	PMID:15598658\|RGD:13461857
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	RGD:2651	Rat	PMID:16192353\|RGD:1601273
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P19491	Rat	PMID:17289840\|RGD:13432317
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P63010	Rat	PMID:20603002\|RGD:8553253
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:Q60838	Rat	PMID:20947020\|RGD:13432314
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P63010	Rat	PMID:25061211\|RGD:13432234
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P13612	Rat	PMID:26779610\|RGD:11344624
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P17301	Rat	PMID:26779610\|RGD:11344624
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P19814	Rat	PMID:9162036\|RGD:8553943
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P19814	Rat	PMID:9341158\|RGD:8554298
Molecular Function	GO:0005515	protein binding	Ap2m1	IPI	UniProtKB:P63010	Rat	PMID:9341158\|RGD:8554298
Molecular Function	GO:0005048	signal sequence binding	AP2M1	IDA		Human	PMID:8918456
Molecular Function	GO:0005048	signal sequence binding	AP2M1	IDA		Human	PMID:9171339
Molecular Function	GO:0005048	signal sequence binding	Ap2m1	IDA		Rat	PMID:12121421\|RGD:10047190
Molecular Function	GO:0044325	transmembrane transporter binding	AP2M1	IPI	UniProtKB:P51787	Human	PMID:23529131
Cellular Component	GO:0030122	AP-2 adaptor complex	AP2M1	IDA		Human	PMID:23676497
Cellular Component	GO:0030122	AP-2 adaptor complex	Ap2m1	IDA		Mouse	MGI:MGI:5514106\|PMID:23676497
Cellular Component	GO:0030122	AP-2 adaptor complex	Ap2m1	IDA		Rat	PMID:12086608\|RGD:12793054
Cellular Component	GO:0005905	clathrin-coated pit	AP2M1	IDA		Human	PMID:31104773
Cellular Component	GO:0070062	extracellular exosome	AP2M1	HDA		Human	PMID:19056867
Cellular Component	GO:0098894	extrinsic component of presynaptic endocytic zone membrane	Ap2m1	IDA		Rat	PMID:8682861\|RGD:155230785
Cellular Component	GO:0098978	glutamatergic synapse	Ap2m1	IDA		Mouse	PMID:24217640
Cellular Component	GO:0098978	glutamatergic synapse	Ap2m1	IMP		Mouse	PMID:24217640
Cellular Component	GO:0098978	glutamatergic synapse	Ap2m1	EXP		Rat	PMID:17289840\|RGD:13432317
Cellular Component	GO:0098978	glutamatergic synapse	Ap2m1	IDA		Rat	PMID:17289840\|RGD:13432317
Cellular Component	GO:0098978	glutamatergic synapse	Ap2m1	IMP		Rat	PMID:17289840\|RGD:13432317
Cellular Component	GO:0005739	mitochondrion	Ap2m1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005886	plasma membrane	AP2M1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045202	synapse	Ap2m1	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Ap2m1	EXP		Mouse	PMID:25211037
Cellular Component	GO:0043195	terminal bouton	Ap2m1	HDA		Rat	PMID:24876496\|RGD:10047219
Biological Process	GO:0072583	clathrin-dependent endocytosis	AP2M1	IDA		Human	PMID:23676497
Biological Process	GO:0072583	clathrin-dependent endocytosis	AP2M1	IDA		Human	PMID:31104773
Biological Process	GO:0072583	clathrin-dependent endocytosis	Ap2m1	IDA		Mouse	MGI:MGI:5514106\|PMID:23676497
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	AP2M1	IMP		Human	PMID:19581412
Biological Process	GO:0002092	positive regulation of receptor internalization	Ap2m1	IMP		Rat	PMID:12105201\|RGD:13461854
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	Ap2m1	IMP		Rat	PMID:19762466\|RGD:13461856
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Ap2m1	IMP		Mouse	PMID:24217640
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Ap2m1	IDA		Mouse	PMID:24217640
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Ap2m1	EXP		Rat	PMID:17289840\|RGD:13432317
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Ap2m1	IDA		Rat	PMID:17289840\|RGD:13432317
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Ap2m1	IMP		Rat	PMID:17289840\|RGD:13432317
Biological Process	GO:0065003	protein-containing complex assembly	Ap2m1	IDA		Rat	PMID:2870069\|RGD:13461855
Biological Process	GO:0031623	receptor internalization	AP2M1	IMP		Human	PMID:25898166
Biological Process	GO:0097494	regulation of vesicle size	AP2M1	IMP		Human	PMID:25898166
Biological Process	GO:0048488	synaptic vesicle endocytosis	AP2M1	IDA		Human	PMID:11102472
Biological Process	GO:0048488	synaptic vesicle endocytosis	AP2M1	IMP		Human	PMID:11102472
Biological Process	GO:0048488	synaptic vesicle endocytosis	Ap2m1	IDA		Rat	PMID:19321783\|RGD:12050109
Biological Process	GO:0048488	synaptic vesicle endocytosis	Ap2m1	IMP		Rat	PMID:19321783\|RGD:12050109
Biological Process	GO:0006900	vesicle budding from membrane	AP2M1	IMP		Human	PMID:25898166
Biological Process	GO:0016055	Wnt signaling pathway	ap2m1a	IGI	ZFIN:ZDB-MRPHLNO-141229-6,ZFIN:ZDB-MRPHLNO-141229-7	Zfish	PMID:25074807
Biological Process	GO:0016055	Wnt signaling pathway	ap2m1b	IGI	ZFIN:ZDB-MRPHLNO-141229-6,ZFIN:ZDB-MRPHLNO-141229-7	Zfish	PMID:25074807

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.