Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AP3D1
  • Mouse genes Ap3d1
  • Rat genes Ap3d1
  • Zfish genes ap3d1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ap3d1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AP3D1	IPI	UniProtKB:Q13286	Human	PMID:15598649
Molecular Function	GO:0005515	protein binding	Ap3d1	IPI	UniProtKB:Q9BRI3	Mouse	MGI:MGI:6839106|PMID:25808614
Molecular Function	GO:0005515	protein binding	Ap3d1	IPI	UniProtKB:D3ZVH6	Rat	PMID:24210660|RGD:10054072
Cellular Component	GO:0030424	axon	Ap3d1	IDA		Mouse	PMID:20089890
Cellular Component	GO:0010008	endosome membrane	AP3D1	IDA		Human	PMID:16162817
Cellular Component	GO:0010008	endosome membrane	Ap3d1	IDA		Mouse	MGI:MGI:3620308|PMID:16162817
Cellular Component	GO:0098978	glutamatergic synapse	Ap3d1	IDA		Mouse	PMID:24217640
Cellular Component	GO:0098978	glutamatergic synapse	Ap3d1	IEP		Mouse	PMID:24217640
Cellular Component	GO:0098978	glutamatergic synapse	Ap3d1	IMP		Mouse	PMID:24217640
Cellular Component	GO:0005765	lysosomal membrane	AP3D1	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	AP3D1	HDA		Human	PMID:19946888
Cellular Component	GO:0098794	postsynapse	Ap3d1	IDA		Mouse	PMID:20089890
Cellular Component	GO:0098793	presynapse	Ap3d1	IDA		Mouse	PMID:20089890
Cellular Component	GO:0098830	presynaptic endosome	Ap3d1	IDA		Mouse	PMID:19144828
Cellular Component	GO:0043195	terminal bouton	Ap3d1	IDA		Mouse	PMID:20089890
Biological Process	GO:0008089	anterograde axonal transport	Ap3d1	IMP		Mouse	MGI:MGI:5437407|PMID:21998198
Biological Process	GO:0048490	anterograde synaptic vesicle transport	Ap3d1	IMP		Mouse	MGI:MGI:5437407|PMID:21998198
Biological Process	GO:0019882	antigen processing and presentation	Ap3d1	IMP	MGI:MGI:1856083	Mouse	PMID:14557411
Biological Process	GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Ap3d1	IMP	MGI:MGI:1856083	Mouse	PMID:14557411
Biological Process	GO:0035646	endosome to melanosome transport	AP3D1	IMP		Human	PMID:22511774
Biological Process	GO:0032607	interferon-alpha production	Ap3d1	IMP		Mouse	PMID:20847273
Biological Process	GO:0006886	intracellular protein transport	Ap3d1	IMP	MGI:MGI:1856083	Mouse	PMID:14557411
Biological Process	GO:0010507	negative regulation of autophagy	ap3d1	IMP	ZFIN:ZDB-GENO-230224-1	Zfish	PMID:35816398
Biological Process	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	Ap3d1	IDA		Mouse	PMID:24217640
Biological Process	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	Ap3d1	IEP		Mouse	PMID:24217640
Biological Process	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	Ap3d1	IMP		Mouse	PMID:24217640
Biological Process	GO:0051138	positive regulation of NK T cell differentiation	Ap3d1	IMP	MGI:MGI:1856083	Mouse	PMID:14557411
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ap3d1	IMP		Mouse	PMID:20847273
Biological Process	GO:0072657	protein localization to membrane	AP3D1	IMP		Human	PMID:22511774
Biological Process	GO:0033365	protein localization to organelle	Ap3d1	IMP	MGI:MGI:1856083	Mouse	PMID:15860731
Biological Process	GO:0045634	regulation of melanocyte differentiation	ap3d1	IMP	ZFIN:ZDB-CRISPR-230222-5	Zfish	PMID:35816398
Biological Process	GO:0045634	regulation of melanocyte differentiation	ap3d1	IMP	ZFIN:ZDB-CRISPR-230222-4	Zfish	PMID:35816398
Biological Process	GO:0045634	regulation of melanocyte differentiation	ap3d1	IMP	ZFIN:ZDB-GENO-230224-1	Zfish	PMID:35816398
Biological Process	GO:0061088	regulation of sequestering of zinc ion	AP3D1	IMP		Human	PMID:17349999
Biological Process	GO:0016182	synaptic vesicle budding from endosome	Ap3d1	IDA		Mouse	PMID:11588176
Biological Process	GO:0016182	synaptic vesicle budding from endosome	Ap3d1	IMP		Mouse	PMID:11588176
Biological Process	GO:0016182	synaptic vesicle budding from endosome	Ap3d1	IDA		Rat	PMID:22539861|RGD:12050120
Biological Process	GO:0016182	synaptic vesicle budding from endosome	Ap3d1	IMP		Rat	PMID:22539861|RGD:12050120
Biological Process	GO:0048499	synaptic vesicle membrane organization	Ap3d1	IMP	MGI:MGI:1856083	Mouse	PMID:15860731
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Ap3d1	IDA		Mouse	PMID:24217640
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Ap3d1	IMP		Mouse	PMID:24217640
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Ap3d1	IEP		Mouse	PMID:24217640

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern