Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APBA3
  • Mouse genes Apba3
  • Rat genes Apba3
  • Zfish genes si:ch73-40i7.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apba3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Apba3	IPI	RGD:736021	Rat	PMID:12196555|RGD:1302262
Molecular Function	GO:0019899	enzyme binding	APBA3	IPI	UniProtKB:Q9NWT6	Human	PMID:19726677
Molecular Function	GO:0004857	enzyme inhibitor activity	APBA3	IDA		Human	PMID:19726677
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:P05067	Human	PMID:10049767
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:A7MCY6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q92844	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q9QYP6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q96P71	Human	PMID:26948053
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q96P71-2	Human	PMID:26948053
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q9NWT6	Human	PMID:26948053
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q96P71-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q9NWT6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:Q9NWT6	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	APBA3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Apba3	IPI	RGD:731724	Rat	PMID:12196555|RGD:1302262
Cellular Component	GO:0048471	perinuclear region of cytoplasm	APBA3	IDA		Human	PMID:19726677
Biological Process	GO:0007268	chemical synaptic transmission	Apba3	IGI	MGI:MGI:1261791	Mouse	PMID:17167098
Biological Process	GO:0007268	chemical synaptic transmission	Apba3	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0001701	in utero embryonic development	Apba3	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0043086	negative regulation of catalytic activity	APBA3	IDA		Human	PMID:19726677
Biological Process	GO:0010468	regulation of gene expression	Apba3	IGI	MGI:MGI:1860297	Mouse	PMID:17167098
Biological Process	GO:0010468	regulation of gene expression	Apba3	IGI	MGI:MGI:1261791	Mouse	PMID:17167098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern