Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Apbb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes APBB1
- Mouse genes Apbb1
- Rat genes Apbb1
- Zfish genes apbb1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apbb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Apbb1	IPI	RGD:2139	Rat	PMID:9461550\|RGD:634556
Molecular Function	GO:0003682	chromatin binding	APBB1	IDA		Human	PMID:19343227
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Apbb1	IPI	UniProtKB:Q12800	Rat	PMID:9685356\|RGD:10054004
Molecular Function	GO:0042393	histone binding	APBB1	IPI	UniProtKB:P16104	Human	PMID:19234442
Molecular Function	GO:0070064	proline-rich region binding	APBB1	IPI	UniProtKB:Q8N8S7	Human	PMID:17686488
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:O94985	Human	PMID:12972431
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067	Human	PMID:16049941
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:O94985	Human	PMID:17332754
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067	Human	PMID:18468999
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P45983	Human	PMID:19234442
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:Q01105	Human	PMID:19343227
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:Q63HK5	Human	PMID:19343227
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067-4	Human	PMID:21968187
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:Q07954	Human	PMID:21968187
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P62330	Human	PMID:24056087
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067	Human	PMID:24284412
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:Q02563	Human	PMID:24284412
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:Q07954	Human	PMID:24284412
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067-4	Human	PMID:26045787
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067-4	Human	PMID:30664241
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067	Human	PMID:8887653
Molecular Function	GO:0005515	protein binding	APBB1	IPI	UniProtKB:P05067	Human	PMID:9461550
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:P12023	Mouse	MGI:MGI:3698695\|PMID:17121854
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:P12023	Mouse	MGI:MGI:3688062\|PMID:11517249
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:A2ARV4	Mouse	MGI:MGI:4949595\|PMID:20637285
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:Q5DTH5\|UniProtKB:Q68FE9\|UniProtKB:Q8CGV9	Mouse	MGI:MGI:4835135\|PMID:19343227
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	PR:Q03173	Mouse	PMID:9407065
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	PR:P12023	Mouse	PMID:8894693
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	PR:Q03157	Mouse	PMID:8894693
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	PR:P12023	Mouse	PMID:16301330
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	PR:Q06335	Mouse	PMID:8894693
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	PR:A2A9I7	Mouse	PMID:9407065
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	RGD:620251	Rat	PMID:16330549\|RGD:2301201
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:Q9JKF8	Rat	PMID:18922798\|RGD:8553468
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:P16104	Rat	PMID:19234442\|RGD:13432336
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:Q99MK2	Rat	PMID:19282473\|RGD:8553580
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	UniProtKB:D3ZKB9	Rat	PMID:19343227\|RGD:8553643
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	RGD:1332566	Rat	PMID:9407065\|RGD:10053999
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	RGD:2128	Rat	PMID:9461550\|RGD:634556
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	RGD:69257	Rat	PMID:9461550\|RGD:634556
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	RGD:1306738	Rat	PMID:9685356\|RGD:10054004
Molecular Function	GO:0005515	protein binding	Apbb1	IPI	RGD:1315527	Rat	PMID:9685356\|RGD:10054004
Molecular Function	GO:0044877	protein-containing complex binding	Apbb1	IPI	RGD:736021\|RGD:621061	Rat	PMID:11441186\|RGD:2301209
Molecular Function	GO:0048156	tau protein binding	Apbb1	IPI	RGD:69329	Rat	PMID:15686969\|RGD:10054042
Molecular Function	GO:0031625	ubiquitin protein ligase binding	APBB1	IPI	UniProtKB:M0R5D6	Human	PMID:25342469
Molecular Function	GO:0031625	ubiquitin protein ligase binding	APBB1	IPI	UniProtKB:Q9D074	Human	PMID:25342469
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Apbb1	IPI	UniProtKB:Q3TEL6	Mouse	MGI:MGI:5818433\|PMID:25342469
Cellular Component	GO:0005737	cytoplasm	APBB1	IDA		Human	PMID:18468999
Cellular Component	GO:0005737	cytoplasm	Apbb1	IDA		Mouse	MGI:MGI:3698695\|PMID:17121854
Cellular Component	GO:0005737	cytoplasm	Apbb1	IDA		Rat	PMID:11085987\|RGD:2301210
Cellular Component	GO:0005737	cytoplasm	Apbb1	IDA		Rat	PMID:18922798\|RGD:8553468
Cellular Component	GO:0005737	cytoplasm	Apbb1	IDA		Rat	PMID:25342469\|RGD:13825435
Cellular Component	GO:0043197	dendritic spine	Apbb1	IDA		Rat	PMID:16330549\|RGD:2301201
Cellular Component	GO:0005783	endoplasmic reticulum	APBB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098978	glutamatergic synapse	Apbb1	IDA		Mouse	PMID:27734846
Cellular Component	GO:0098978	glutamatergic synapse	Apbb1	IMP		Mouse	PMID:27734846
Cellular Component	GO:0030426	growth cone	APBB1	IDA		Human	PMID:12843239
Cellular Component	GO:0030426	growth cone	Apbb1	IDA		Rat	PMID:19343227\|RGD:8553643
Cellular Component	GO:1990812	growth cone filopodium	Apbb1	IDA		Rat	PMID:12843239\|RGD:10053998
Cellular Component	GO:1990761	growth cone lamellipodium	Apbb1	IDA		Rat	PMID:12843239\|RGD:10053998
Cellular Component	GO:0030027	lamellipodium	APBB1	IDA		Human	PMID:12843239
Cellular Component	GO:0044304	main axon	Apbb1	IDA		Rat	PMID:12843239\|RGD:10053998
Cellular Component	GO:0031594	neuromuscular junction	Apbb1	IMP		Mouse	PMID:27734846
Cellular Component	GO:0031594	neuromuscular junction	Apbb1	IDA		Mouse	PMID:27734846
Cellular Component	GO:0043025	neuronal cell body	Apbb1	IDA		Rat	PMID:22429478\|RGD:10054018
Cellular Component	GO:0005634	nucleus	APBB1	IDA		Human	PMID:18468999
Cellular Component	GO:0005634	nucleus	APBB1	IDA		Human	PMID:19343227
Cellular Component	GO:0005634	nucleus	Apbb1	IDA		Mouse	MGI:MGI:3698695\|PMID:17121854
Cellular Component	GO:0005634	nucleus	Apbb1	IDA		Rat	PMID:12089154\|RGD:127285400
Cellular Component	GO:0005634	nucleus	Apbb1	IDA		Rat	PMID:18304449\|RGD:2301198
Cellular Component	GO:0005634	nucleus	Apbb1	IDA		Rat	PMID:18922798\|RGD:8553468
Cellular Component	GO:0005634	nucleus	Apbb1	IDA		Rat	PMID:19282473\|RGD:8553580
Cellular Component	GO:0005634	nucleus	Apbb1	IDA		Rat	PMID:25342469\|RGD:13825435
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Apbb1	IDA		Rat	PMID:10075692\|RGD:2301211
Cellular Component	GO:0005886	plasma membrane	APBB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	APBB1	IDA		Human	PMID:18468999
Cellular Component	GO:0045211	postsynaptic membrane	Apbb1	IDA		Rat	PMID:16330549\|RGD:2301201
Cellular Component	GO:0098793	presynapse	Apbb1	IDA		Rat	PMID:12843239\|RGD:10053998
Cellular Component	GO:0042734	presynaptic membrane	Apbb1	IDA		Rat	PMID:16330549\|RGD:2301201
Cellular Component	GO:0032991	protein-containing complex	Apbb1	IDA		Rat	PMID:11441186\|RGD:2301209
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apbb1	IDA		Mouse	PMID:27734846
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Apbb1	IMP		Mouse	PMID:27734846
Cellular Component	GO:0045202	synapse	APBB1	IDA		Human	PMID:12843239
Biological Process	GO:0007411	axon guidance	Apbb1	IGI	MGI:MGI:108405	Mouse	PMID:16407979
Biological Process	GO:0006974	DNA damage response	APBB1	IDA		Human	PMID:18468999
Biological Process	GO:0006974	DNA damage response	Apbb1	IDA		Mouse	MGI:MGI:3698695\|PMID:17121854
Biological Process	GO:0006302	double-strand break repair	Apbb1	IMP		Mouse	MGI:MGI:3698695\|PMID:17121854
Biological Process	GO:0006302	double-strand break repair	Apbb1	IMP		Rat	PMID:19282473\|RGD:8553580
Biological Process	GO:0030198	extracellular matrix organization	Apbb1	IGI	MGI:MGI:108405	Mouse	PMID:16407979
Biological Process	GO:0043967	histone H4 acetylation	Apbb1	IMP		Rat	PMID:19282473\|RGD:8553580
Biological Process	GO:1902807	negative regulation of cell cycle G1/S phase transition	Apbb1	IDA		Rat	PMID:12089154\|RGD:127285400
Biological Process	GO:0045665	negative regulation of neuron differentiation	Apbb1	IMP	MGI:MGI:3514266	Mouse	PMID:18278038
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	APBB1	IGI	UniProtKB:P05067:PRO_0000000099	Human	PMID:21803450
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Apbb1	IDA		Rat	PMID:12089154\|RGD:127285400
Biological Process	GO:0030182	neuron differentiation	Apbb1	IMP	MGI:MGI:3514266	Mouse	PMID:18278038
Biological Process	GO:0001764	neuron migration	Apbb1	IGI	MGI:MGI:108405	Mouse	PMID:16407979
Biological Process	GO:0043065	positive regulation of apoptotic process	APBB1	IDA		Human	PMID:18468999
Biological Process	GO:0043065	positive regulation of apoptotic process	Apbb1	IMP		Rat	PMID:25342469\|RGD:13825435
Biological Process	GO:0045739	positive regulation of DNA repair	Apbb1	IMP		Mouse	MGI:MGI:3698695\|PMID:17121854
Biological Process	GO:0045739	positive regulation of DNA repair	Apbb1	IMP		Rat	PMID:19282473\|RGD:8553580
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	APBB1	IDA		Human	PMID:19343227
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Apbb1	IDA		Rat	PMID:18922798\|RGD:8553468
Biological Process	GO:0010976	positive regulation of neuron projection development	Apbb1	IMP		Rat	PMID:24056087\|RGD:10054024
Biological Process	GO:0050714	positive regulation of protein secretion	Apbb1	IMP		Rat	PMID:10075692\|RGD:2301211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Apbb1	IGI	MGI:MGI:1932051	Mouse	PMID:15944124
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Apbb1	IGI	MGI:MGI:88059	Mouse	PMID:15944124
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Apbb1	IDA		Rat	PMID:11441186\|RGD:2301209
Biological Process	GO:0010039	response to iron ion	Apbb1	IEP		Rat	PMID:18723004\|RGD:2301196
Biological Process	GO:0006939	smooth muscle contraction	Apbb1	IMP		Mouse	MGI:MGI:5648704\|PMID:25757569
Biological Process	GO:0050808	synapse organization	Apbb1	IDA		Mouse	PMID:27734846
Biological Process	GO:0050808	synapse organization	Apbb1	IMP		Mouse	PMID:27734846

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.