Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APBB2
  • Mouse genes Apbb2
  • Rat genes Apbb2
  • Zfish genes apbb2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apbb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:P05067	Human	PMID:14527950
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:P05067	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:P05067	Human	PMID:8855266
Molecular Function	GO:0005515	protein binding	APBB2	IPI	UniProtKB:Q06481	Human	PMID:8855266
Molecular Function	GO:0005515	protein binding	Apbb2	IPI	UniProtKB:P12023	Mouse	MGI:MGI:3820848|PMID:18650440
Molecular Function	GO:0005515	protein binding	Apbb2	IPI	PR:Q91Y86	Mouse	PMID:15629131
Cellular Component	GO:0005737	cytoplasm	Apbb2	IDA		Mouse	PMID:15629131
Cellular Component	GO:0005769	early endosome	APBB2	IDA		Human	PMID:14527950
Cellular Component	GO:0005783	endoplasmic reticulum	APBB2	IDA		Human	PMID:14527950
Cellular Component	GO:0005794	Golgi apparatus	APBB2	IDA		Human	PMID:14527950
Cellular Component	GO:0005634	nucleus	APBB2	IDA		Human	PMID:12089154
Biological Process	GO:0007411	axon guidance	Apbb2	IGI	MGI:MGI:107765	Mouse	PMID:16407979
Biological Process	GO:0030198	extracellular matrix organization	Apbb2	IGI	MGI:MGI:107765	Mouse	PMID:16407979
Biological Process	GO:0036438	maintenance of lens transparency	Apbb2	IMP		Mouse	MGI:MGI:5648704|PMID:25757569
Biological Process	GO:0043066	negative regulation of apoptotic process	Apbb2	IGI	MGI:MGI:99255	Mouse	PMID:15629131
Biological Process	GO:0043066	negative regulation of apoptotic process	Apbb2	IGI	MGI:MGI:104798	Mouse	PMID:15629131
Biological Process	GO:1901988	negative regulation of cell cycle phase transition	APBB2	IDA		Human	PMID:12089154
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	APBB2	IDA		Human	PMID:12089154
Biological Process	GO:0001764	neuron migration	Apbb2	IGI	MGI:MGI:107765	Mouse	PMID:16407979
Biological Process	GO:0043065	positive regulation of apoptotic process	Apbb2	IDA		Mouse	PMID:15629131
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	APBB2	IDA		Human	PMID:14527950
Biological Process	GO:0006939	smooth muscle contraction	Apbb2	IMP		Mouse	MGI:MGI:5648704|PMID:25757569

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern