Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APIP
  • Mouse genes Apip
  • Rat genes Apip
  • Zfish genes apip
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	APIP	IPI	UniProtKB:Q96GX9	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	APIP	IPI	UniProtKB:Q96GX9	Human	PMID:19060904
Molecular Function	GO:0042802	identical protein binding	APIP	IPI	UniProtKB:Q96GX9	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	APIP	IPI	UniProtKB:Q96GX9	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	APIP	IPI	UniProtKB:Q96GX9	Human	PMID:32296183
Molecular Function	GO:0046570	methylthioribulose 1-phosphate dehydratase activity	APIP	IDA		Human	PMID:24367089
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q6ZVK8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q8TBB1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q6ZVK8	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:O14787	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:P12268	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:P24278	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:P25786	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:P63208	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q17RL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q8IYR0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q96HA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q9Y3Q8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q8TBB1	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:O14787	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q17RL8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q6ZVK8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q9UIF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APIP	IPI	UniProtKB:Q16637	Human	PMID:32814053
Molecular Function	GO:0008270	zinc ion binding	APIP	IDA		Human	PMID:24367089
Cellular Component	GO:0005737	cytoplasm	APIP	IDA		Human	PMID:23285211
Biological Process	GO:0006915	apoptotic process	Apip	IMP		Mouse	PMID:15262985
Biological Process	GO:0019509	L-methionine salvage from methylthioadenosine	APIP	IMP		Human	PMID:22837397
Biological Process	GO:0019509	L-methionine salvage from methylthioadenosine	APIP	IMP		Human	PMID:23285211
Biological Process	GO:0043066	negative regulation of apoptotic process	APIP	IMP		Human	PMID:22837397
Biological Process	GO:0043066	negative regulation of apoptotic process	APIP	IMP		Human	PMID:24367089
Biological Process	GO:0043066	negative regulation of apoptotic process	Apip	IMP		Mouse	MGI:MGI:5486555|PMID:17086211
Biological Process	GO:0043066	negative regulation of apoptotic process	Apip	IMP		Mouse	PMID:15262985
Biological Process	GO:0051289	protein homotetramerization	APIP	IDA		Human	PMID:24367089
Biological Process	GO:0070269	pyroptosis	APIP	IMP		Human	PMID:24367089
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	Apip	IMP		Mouse	MGI:MGI:5486555|PMID:17086211

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern