Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOA5
  • Mouse genes Apoa5
  • Rat genes Apoa5
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apoa5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008047	enzyme activator activity	APOA5	IDA		Human	PMID:16806135
Molecular Function	GO:0019899	enzyme binding	APOA5	IDA		Human	PMID:15178420
Molecular Function	GO:0008201	heparin binding	APOA5	IDA		Human	PMID:15878877
Molecular Function	GO:0008201	heparin binding	APOA5	IDA		Human	PMID:17326667
Molecular Function	GO:0060229	lipase activator activity	APOA5	IMP		Human	PMID:15178420
Molecular Function	GO:0035473	lipase binding	APOA5	IPI	UniProtKB:P06858	Human	PMID:15178420
Molecular Function	GO:0008289	lipid binding	APOA5	IDA		Human	PMID:12810715
Molecular Function	GO:0060230	lipoprotein lipase activator activity	APOA5	IDA		Human	PMID:18635818
Molecular Function	GO:0070325	lipoprotein particle receptor binding	APOA5	IPI	UniProtKB:P98165	Human	PMID:18635818
Molecular Function	GO:0070325	lipoprotein particle receptor binding	APOA5	IPI	UniProtKB:Q07954	Human	PMID:18635818
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	APOA5	IPI	UniProtKB:Q07954	Human	PMID:17326667
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	APOA5	IPI	UniProtKB:Q92673	Human	PMID:17326667
Molecular Function	GO:0031210	phosphatidylcholine binding	APOA5	IDA		Human	PMID:16806135
Molecular Function	GO:0005543	phospholipid binding	APOA5	IDA		Human	PMID:12810715
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:O95070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:P49638	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q8NDC4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q96CM8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q96MX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q9BQE4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q9BTV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q9HB07	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOA5	IPI	UniProtKB:Q9NX76	Human	PMID:32296183
Cellular Component	GO:0042627	chylomicron	APOA5	IDA		Human	PMID:15528295
Cellular Component	GO:0005576	extracellular region	APOA5	IDA		Human	PMID:11577099
Cellular Component	GO:0005615	extracellular space	APOA5	IDA		Human	PMID:18635818
Cellular Component	GO:0005615	extracellular space	APOA5	IDA		Human	PMID:19121291
Cellular Component	GO:0005615	extracellular space	Apoa5	IDA		Rat	PMID:19694729|RGD:2313326
Cellular Component	GO:0034364	high-density lipoprotein particle	APOA5	IDA		Human	PMID:15528295
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOA5	IDA		Human	PMID:15528295
Biological Process	GO:0055090	acylglycerol homeostasis	APOA5	IDA		Human	PMID:11588264
Biological Process	GO:0055090	acylglycerol homeostasis	APOA5	IMP		Human	PMID:15178420
Biological Process	GO:0055090	acylglycerol homeostasis	Apoa5	IMP		Mouse	MGI:MGI:2151719|PMID:11588264
Biological Process	GO:0031100	animal organ regeneration	Apoa5	IEP		Rat	PMID:11577099|RGD:70662
Biological Process	GO:0042632	cholesterol homeostasis	APOA5	IDA		Human	PMID:19121291
Biological Process	GO:0006869	lipid transport	APOA5	IDA		Human	PMID:15178420
Biological Process	GO:0006869	lipid transport	Apoa5	IMP		Rat	PMID:11588264|RGD:631983
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	APOA5	IDA		Human	PMID:18635818
Biological Process	GO:0050996	positive regulation of lipid catabolic process	APOA5	IDA		Human	PMID:16806135
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	APOA5	IDA		Human	PMID:15178420
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	APOA5	IDA		Human	PMID:16806135
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	APOA5	IDA		Human	PMID:18635818
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	APOA5	IDA		Human	PMID:18635818
Biological Process	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	APOA5	IDA		Human	PMID:18635818
Biological Process	GO:0009725	response to hormone	Apoa5	IEP		Rat	PMID:15941710|RGD:1601661
Biological Process	GO:0042246	tissue regeneration	APOA5	IEP		Human	PMID:11577099
Biological Process	GO:0019433	triglyceride catabolic process	APOA5	IMP		Human	PMID:15178420
Biological Process	GO:0070328	triglyceride homeostasis	APOA5	IMP		Human	PMID:18635818
Biological Process	GO:0070328	triglyceride homeostasis	APOA5	IDA		Human	PMID:19121291
Biological Process	GO:0006641	triglyceride metabolic process	APOA5	IDA		Human	PMID:11588264
Biological Process	GO:0006641	triglyceride metabolic process	APOA5	IMP		Human	PMID:12417525
Biological Process	GO:0006641	triglyceride metabolic process	APOA5	IMP		Human	PMID:14729863
Biological Process	GO:0006641	triglyceride metabolic process	APOA5	IMP		Human	PMID:17142127
Biological Process	GO:0006641	triglyceride metabolic process	Apoa5	IMP	MGI:MGI:3609233	Mouse	PMID:16166565
Biological Process	GO:0034370	triglyceride-rich lipoprotein particle remodeling	Apoa5	IMP	MGI:MGI:3609233	Mouse	PMID:16166565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern