Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOBEC1
  • Mouse genes Apobec1
  • Rat genes Apobec1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apobec1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004126	cytidine deaminase activity	Apobec1	IDA		Rat	PMID:15448152|RGD:8554599
Molecular Function	GO:0004126	cytidine deaminase activity	Apobec1	IDA		Rat	PMID:8511591|RGD:634661
Molecular Function	GO:0004131	cytosine deaminase activity	Apobec1	IDA		Rat	PMID:12697753|RGD:1358271
Molecular Function	GO:0008047	enzyme activator activity	Apobec1	IDA		Rat	PMID:9792439|RGD:10041038
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	Apobec1	IDA		Mouse	PMID:15480992
Molecular Function	GO:0003729	mRNA binding	Apobec1	IDA		Rat	PMID:9792439|RGD:10041038
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:Q9NQ94	Human	PMID:10669759
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:A0AV96	Human	PMID:24916387
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:A8MTQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:P52597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:P61978-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:Q00534	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:Q3LI64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:Q3LI72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC1	IPI	UniProtKB:Q9NUQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Apobec1	IPI	PR:Q91WT8	Mouse	PMID:24916387
Molecular Function	GO:0005515	protein binding	Apobec1	IPI	UniProtKB:Q923K9	Rat	PMID:10781591|RGD:8553657
Molecular Function	GO:0019904	protein domain specific binding	Apobec1	IPI	RGD:1309982	Rat	PMID:9792439|RGD:10041038
Molecular Function	GO:0043021	ribonucleoprotein complex binding	Apobec1	IPI	RGD:1309982	Rat	PMID:9792439|RGD:10041038
Cellular Component	GO:0030895	apolipoprotein B mRNA editing enzyme complex	APOBEC1	IDA		Human	PMID:24916387
Cellular Component	GO:0005737	cytoplasm	APOBEC1	IDA		Human	PMID:22580899
Cellular Component	GO:0005737	cytoplasm	Apobec1	IDA		Rat	PMID:9371802|RGD:8693735
Cellular Component	GO:0005634	nucleus	APOBEC1	IDA		Human	PMID:12881431
Cellular Component	GO:0005634	nucleus	APOBEC1	IDA		Human	PMID:24916387
Cellular Component	GO:0005634	nucleus	Apobec1	IDA		Rat	PMID:9371802|RGD:8693735
Biological Process	GO:0032869	cellular response to insulin stimulus	Apobec1	IEP		Rat	PMID:9667237|RGD:1626288
Biological Process	GO:0016554	cytidine to uridine editing	APOBEC1	IDA		Human	PMID:24916387
Biological Process	GO:0016554	cytidine to uridine editing	APOBEC1	IDA		Human	PMID:30844405
Biological Process	GO:0016554	cytidine to uridine editing	Apobec1	IDA		Mouse	MGI:MGI:7387172|PMID:30844405
Biological Process	GO:0016554	cytidine to uridine editing	Apobec1	IGI	MGI:MGI:1917115	Mouse	PMID:24916387
Biological Process	GO:0016554	cytidine to uridine editing	Apobec1	IMP	MGI:MGI:2157378	Mouse	PMID:8692961
Biological Process	GO:0016554	cytidine to uridine editing	Apobec1	IGI	MGI:MGI:2384294	Mouse	PMID:24916387
Biological Process	GO:0016554	cytidine to uridine editing	Apobec1	IDA		Rat	PMID:12020819|RGD:625559
Biological Process	GO:0051607	defense response to virus	Apobec1	IDA		Rat	PMID:15296758|RGD:1626281
Biological Process	GO:0070383	DNA cytosine deamination	Apobec1	IDA		Rat	PMID:12697753|RGD:1358271
Biological Process	GO:0080111	DNA demethylation	Apobec1	IDA		Mouse	MGI:MGI:5285126|PMID:21496894
Biological Process	GO:0051649	establishment of localization in cell	Apobec1	IGI	MGI:MGI:88052	Mouse	PMID:13130124
Biological Process	GO:0042158	lipoprotein biosynthetic process	Apobec1	IGI	MGI:MGI:88052	Mouse	PMID:13130124
Biological Process	GO:0042157	lipoprotein metabolic process	Apobec1	IMP	MGI:MGI:2157378	Mouse	PMID:8692961
Biological Process	GO:0042953	lipoprotein transport	Apobec1	IGI	MGI:MGI:88052	Mouse	PMID:13130124
Biological Process	GO:0016556	mRNA modification	APOBEC1	IDA		Human	PMID:11134005
Biological Process	GO:0016556	mRNA modification	Apobec1	IMP	MGI:MGI:2157186	Mouse	PMID:8626621
Biological Process	GO:0016556	mRNA modification	Apobec1	IMP	MGI:MGI:3664540	Mouse	PMID:9240444
Biological Process	GO:0016556	mRNA modification	Apobec1	IDA		Mouse	PMID:10403781
Biological Process	GO:0016556	mRNA modification	Apobec1	IMP	MGI:MGI:2157378	Mouse	PMID:8692961
Biological Process	GO:0016556	mRNA modification	Apobec1	IDA		Rat	PMID:8511591|RGD:634661
Biological Process	GO:0048255	mRNA stabilization	Apobec1	IDA		Mouse	PMID:15480992
Biological Process	GO:0090310	negative regulation of DNA methylation-dependent heterochromatin formation	Apobec1	IMP		Mouse	MGI:MGI:5285126|PMID:21496894
Biological Process	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	APOBEC1	IDA		Human	PMID:12881431
Biological Process	GO:0090209	negative regulation of triglyceride metabolic process	Apobec1	IGI	MGI:MGI:88057	Mouse	PMID:9240444
Biological Process	GO:0090366	positive regulation of mRNA modification	Apobec1	IDA		Rat	PMID:9792439|RGD:10041038
Biological Process	GO:0042127	regulation of cell population proliferation	Apobec1	IGI	MGI:MGI:88039	Mouse	PMID:17875695
Biological Process	GO:0051592	response to calcium ion	Apobec1	IDA		Rat	PMID:11027667|RGD:1626282
Biological Process	GO:0045471	response to ethanol	Apobec1	IDA		Rat	PMID:9826530|RGD:1626287
Biological Process	GO:0010332	response to gamma radiation	Apobec1	IMP	MGI:MGI:2157186	Mouse	PMID:15480992
Biological Process	GO:0006970	response to osmotic stress	Apobec1	IDA		Rat	PMID:10939631|RGD:1626285
Biological Process	GO:0009410	response to xenobiotic stimulus	Apobec1	IDA		Rat	PMID:11116209|RGD:1626277
Biological Process	GO:0010043	response to zinc ion	Apobec1	IEP		Rat	PMID:10498758|RGD:1626286
Biological Process	GO:0006641	triglyceride metabolic process	Apobec1	IGI	MGI:MGI:88057	Mouse	PMID:9240444

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern