Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOBEC2
  • Mouse genes Apobec2
  • Rat genes Apobec2
  • Zfish genes apobec2a,apobec2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apobec2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004126	cytidine deaminase activity	APOBEC2	IDA		Human	PMID:10403781
Molecular Function	GO:0004126	cytidine deaminase activity	Apobec2	IDA		Mouse	PMID:10403781
Molecular Function	GO:0042802	identical protein binding	APOBEC2	IPI	UniProtKB:Q9Y235	Human	PMID:17187054
Molecular Function	GO:0005515	protein binding	apobec2a	IPI	ZFIN:ZDB-GENE-110728-3	Zfish	PMID:25190811
Molecular Function	GO:0005515	protein binding	apobec2a	IPI	ZFIN:ZDB-GENE-990614-17	Zfish	PMID:25190811
Molecular Function	GO:0005515	protein binding	apobec2a	IPI	ZFIN:ZDB-GENE-091118-71	Zfish	PMID:25190811
Molecular Function	GO:0005515	protein binding	apobec2b	IPI	ZFIN:ZDB-GENE-091118-71	Zfish	PMID:25190811
Molecular Function	GO:0005515	protein binding	apobec2b	IPI	ZFIN:ZDB-GENE-990614-17	Zfish	PMID:25190811
Molecular Function	GO:0005515	protein binding	apobec2b	IPI	ZFIN:ZDB-GENE-110728-3	Zfish	PMID:25190811
Biological Process	GO:0043697	cell dedifferentiation	apobec2a	IMP	ZFIN:ZDB-MRPHLNO-090618-1	Zfish	PMID:22262907
Biological Process	GO:0043697	cell dedifferentiation	apobec2b	IMP	ZFIN:ZDB-MRPHLNO-090618-2	Zfish	PMID:22262907
Biological Process	GO:0016554	cytidine to uridine editing	APOBEC2	IDA		Human	PMID:10403781
Biological Process	GO:0016554	cytidine to uridine editing	Apobec2	IDA		Mouse	PMID:10403781
Biological Process	GO:0080111	DNA demethylation	APOBEC2	IDA		Human	PMID:21496894
Biological Process	GO:0001947	heart looping	apobec2a	IMP	ZFIN:ZDB-MRPHLNO-110302-4	Zfish	PMID:20880495
Biological Process	GO:0016556	mRNA modification	Apobec2	IMP	MGI:MGI:2157186	Mouse	PMID:8626621
Biological Process	GO:0043388	positive regulation of DNA binding	apobec2a	IDA		Zfish	PMID:25190811
Biological Process	GO:0043388	positive regulation of DNA binding	apobec2b	IDA		Zfish	PMID:25190811
Biological Process	GO:0031099	regeneration	apobec2a	IGI	ZFIN:ZDB-MRPHLNO-090618-1,ZFIN:ZDB-MRPHLNO-090618-2	Zfish	PMID:25190811
Biological Process	GO:0031099	regeneration	apobec2b	IGI	ZFIN:ZDB-MRPHLNO-090618-1,ZFIN:ZDB-MRPHLNO-090618-2	Zfish	PMID:25190811
Biological Process	GO:0070654	sensory epithelium regeneration	apobec2a	IMP	ZFIN:ZDB-MRPHLNO-090618-1	Zfish	PMID:22262907
Biological Process	GO:0070654	sensory epithelium regeneration	apobec2b	IMP	ZFIN:ZDB-MRPHLNO-090618-2	Zfish	PMID:22262907
Biological Process	GO:0060538	skeletal muscle organ development	apobec2a	IMP	ZFIN:ZDB-MRPHLNO-100618-3	Zfish	PMID:20440001
Biological Process	GO:0060538	skeletal muscle organ development	apobec2b	IMP	ZFIN:ZDB-MRPHLNO-090618-2	Zfish	PMID:20440001

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern