Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOBEC3B,APOBEC3C,APOBEC3D,APOBEC3F,APOBEC3G
  • Mouse genes Apobec3
  • Rat genes Apobec3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apobec3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004126	cytidine deaminase activity	APOBEC3F	IDA		Human	PMID:17121840
Molecular Function	GO:0047844	deoxycytidine deaminase activity	APOBEC3G	IDA		Human	PMID:12808465
Molecular Function	GO:0047844	deoxycytidine deaminase activity	APOBEC3B	IMP		Human	PMID:22457529
Molecular Function	GO:0042802	identical protein binding	APOBEC3F	IPI	UniProtKB:Q8IUX4	Human	PMID:23685212
Molecular Function	GO:0042802	identical protein binding	APOBEC3G	IPI	UniProtKB:Q9HC16	Human	PMID:11863358
Molecular Function	GO:0042802	identical protein binding	APOBEC3G	IPI	UniProtKB:Q9HC16	Human	PMID:15152192
Molecular Function	GO:0042802	identical protein binding	APOBEC3G	IPI	UniProtKB:Q9HC16	Human	PMID:20152150
Molecular Function	GO:0005515	protein binding	APOBEC3F	IPI	UniProtKB:Q9HC16	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3F	IPI	UniProtKB:Q9H9G7	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3F	IPI	UniProtKB:Q9UKV8	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3F	IPI	UniProtKB:Q9UL18	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:P69723	Human	PMID:14528301
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:P69723	Human	PMID:15152192
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:P06730	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:P26196	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q8IU60	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q8IUX4	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q9NRA8	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q9UKV8	Human	PMID:16699599
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:P17612	Human	PMID:18836454
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q77YG0	Human	PMID:18836454
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q77YG0	Human	PMID:19887642
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q9H9G7	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q9UKV8	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3G	IPI	UniProtKB:Q9UL18	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q9UKV8	Human	PMID:22915799
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:P0DJD3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:P38159	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q15415	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:P15622-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:P38159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:P61978-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:P79522	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q03014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q15415	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q96MX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q96RU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q9H9D4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q9P0T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3C	IPI	UniProtKB:Q9Y3Y2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOBEC3B	IPI	UniProtKB:P11802	Human	PMID:31217276
Molecular Function	GO:0005515	protein binding	Apobec3	IPI	UniProtKB:Q6VY05	Mouse	MGI:MGI:3796258|PMID:18509452
Molecular Function	GO:0003723	RNA binding	APOBEC3F	IDA		Human	PMID:11863358
Molecular Function	GO:0003723	RNA binding	APOBEC3F	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	APOBEC3G	IDA		Human	PMID:11863358
Molecular Function	GO:0003723	RNA binding	APOBEC3C	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	APOBEC3C	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	APOBEC3B	HDA		Human	PMID:22681889
Molecular Function	GO:0008270	zinc ion binding	APOBEC3F	IDA		Human	PMID:11863358
Molecular Function	GO:0008270	zinc ion binding	APOBEC3G	IDA		Human	PMID:11863358
Cellular Component	GO:0005737	cytoplasm	APOBEC3F	IDA		Human	PMID:16527742
Cellular Component	GO:0005737	cytoplasm	APOBEC3F	IDA		Human	PMID:16699599
Cellular Component	GO:0005737	cytoplasm	APOBEC3F	IDA		Human	PMID:21835787
Cellular Component	GO:0005737	cytoplasm	APOBEC3D	IDA		Human	PMID:21835787
Cellular Component	GO:0005737	cytoplasm	APOBEC3G	IDA		Human	PMID:16527742
Cellular Component	GO:0005737	cytoplasm	APOBEC3G	IDA		Human	PMID:16699599
Cellular Component	GO:0005737	cytoplasm	APOBEC3G	IDA		Human	PMID:21835787
Cellular Component	GO:0005737	cytoplasm	APOBEC3C	IDA		Human	PMID:21835787
Cellular Component	GO:0005737	cytoplasm	Apobec3	IDA		Mouse	MGI:MGI:5285175|PMID:16527742
Cellular Component	GO:0005654	nucleoplasm	APOBEC3B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	APOBEC3C	IDA		Human	PMID:21835787
Cellular Component	GO:0005634	nucleus	APOBEC3B	IDA		Human	PMID:16699599
Cellular Component	GO:0005634	nucleus	APOBEC3B	IDA		Human	PMID:21835787
Cellular Component	GO:0000932	P-body	APOBEC3F	IDA		Human	PMID:16699599
Cellular Component	GO:0000932	P-body	APOBEC3F	IDA		Human	PMID:22915799
Cellular Component	GO:0000932	P-body	APOBEC3D	IDA		Human	PMID:22915799
Cellular Component	GO:0000932	P-body	APOBEC3G	IDA		Human	PMID:16699599
Cellular Component	GO:0000932	P-body	APOBEC3G	IDA		Human	PMID:22915799
Cellular Component	GO:1990904	ribonucleoprotein complex	APOBEC3F	IDA		Human	PMID:16699599
Cellular Component	GO:1990904	ribonucleoprotein complex	APOBEC3G	IDA		Human	PMID:16699599
Biological Process	GO:0016553	base conversion or substitution editing	APOBEC3F	IDA		Human	PMID:17121840
Biological Process	GO:0009972	cytidine deamination	APOBEC3G	IDA		Human	PMID:16378963
Biological Process	GO:0009972	cytidine deamination	APOBEC3C	IDA		Human	PMID:21632763
Biological Process	GO:0051607	defense response to virus	APOBEC3F	IDA		Human	PMID:21835787
Biological Process	GO:0051607	defense response to virus	APOBEC3F	IDA		Human	PMID:22915799
Biological Process	GO:0051607	defense response to virus	APOBEC3D	IDA		Human	PMID:21835787
Biological Process	GO:0051607	defense response to virus	APOBEC3G	IDA		Human	PMID:12808465
Biological Process	GO:0051607	defense response to virus	APOBEC3G	IDA		Human	PMID:21835787
Biological Process	GO:0051607	defense response to virus	APOBEC3G	IDA		Human	PMID:22915799
Biological Process	GO:0051607	defense response to virus	APOBEC3B	IDA		Human	PMID:22457529
Biological Process	GO:0051607	defense response to virus	APOBEC3B	IDA		Human	PMID:22915799
Biological Process	GO:0070383	DNA cytosine deamination	APOBEC3F	IDA		Human	PMID:21835787
Biological Process	GO:0070383	DNA cytosine deamination	APOBEC3D	IDA		Human	PMID:21835787
Biological Process	GO:0070383	DNA cytosine deamination	APOBEC3G	IDA		Human	PMID:16527742
Biological Process	GO:0070383	DNA cytosine deamination	APOBEC3G	IDA		Human	PMID:16571802
Biological Process	GO:0070383	DNA cytosine deamination	APOBEC3G	IDA		Human	PMID:21835787
Biological Process	GO:0080111	DNA demethylation	APOBEC3F	IDA		Human	PMID:21496894
Biological Process	GO:0080111	DNA demethylation	APOBEC3C	IDA		Human	PMID:21496894
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Apobec3	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0045087	innate immune response	APOBEC3F	IDA		Human	PMID:17121840
Biological Process	GO:0045087	innate immune response	APOBEC3G	IDA		Human	PMID:17121840
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3F	IDA		Human	PMID:17121840
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3F	IDA		Human	PMID:21835787
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3D	IDA		Human	PMID:21835787
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3G	IDA		Human	PMID:16571802
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3G	IDA		Human	PMID:17121840
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3G	IDA		Human	PMID:21835787
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3F	IDA		Human	PMID:16527742
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3F	IDA		Human	PMID:20062055
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3D	IDA		Human	PMID:20062055
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3G	IDA		Human	PMID:16527742
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3C	IDA		Human	PMID:16527742
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3C	IDA		Human	PMID:20062055
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3B	IDA		Human	PMID:16527742
Biological Process	GO:0010529	negative regulation of transposition	APOBEC3B	IDA		Human	PMID:20062055
Biological Process	GO:0010529	negative regulation of transposition	Apobec3	IDA		Mouse	MGI:MGI:5285175|PMID:16527742
Biological Process	GO:0045071	negative regulation of viral genome replication	APOBEC3F	IDA		Human	PMID:16378963
Biological Process	GO:0045071	negative regulation of viral genome replication	APOBEC3F	IDA		Human	PMID:17121840
Biological Process	GO:0045071	negative regulation of viral genome replication	APOBEC3G	IDA		Human	PMID:16378963
Biological Process	GO:0045071	negative regulation of viral genome replication	APOBEC3G	IDA		Human	PMID:17121840
Biological Process	GO:0045071	negative regulation of viral genome replication	APOBEC3C	IDA		Human	PMID:21632763
Biological Process	GO:0045071	negative regulation of viral genome replication	Apobec3	IDA		Mouse	MGI:MGI:5486557|PMID:16378963
Biological Process	GO:0048525	negative regulation of viral process	APOBEC3F	IDA		Human	PMID:17121840
Biological Process	GO:0048525	negative regulation of viral process	APOBEC3G	IDA		Human	PMID:17121840
Biological Process	GO:0002230	positive regulation of defense response to virus by host	APOBEC3F	IDA		Human	PMID:17121840
Biological Process	GO:0002230	positive regulation of defense response to virus by host	APOBEC3G	IDA		Human	PMID:17121840
Biological Process	GO:0050688	regulation of defense response to virus	Apobec3	IMP	MGI:MGI:3809768	Mouse	PMID:293683
Biological Process	GO:1903900	regulation of viral life cycle	Apobec3	IMP	MGI:MGI:3809768	Mouse	PMID:293683

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern