Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOC1
  • Mouse genes Apoc1
  • Rat genes Apoc1
  • Zfish genes apoc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apoc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005504	fatty acid binding	APOC1	IDA		Human	PMID:17339654
Molecular Function	GO:0055102	lipase inhibitor activity	APOC1	IDA		Human	PMID:15576844
Molecular Function	GO:0055102	lipase inhibitor activity	APOC1	IDA		Human	PMID:182536
Molecular Function	GO:0004859	phospholipase inhibitor activity	APOC1	IDA		Human	PMID:2302419
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:A8MV81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:O00241-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:O95563	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:P56378-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q13085-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q14D33	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q17RD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q53QW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q5XKP0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q6P1Q0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q6VB84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q6ZUI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q8N5I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q8WWC4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q8WXG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q96CM8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q96E29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q96JH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q96QA5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q99525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q9UMS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOC1	IPI	UniProtKB:Q9Y6C9	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	APOC1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0034364	high-density lipoprotein particle	APOC1	IDA		Human	PMID:15576844
Cellular Component	GO:0034364	high-density lipoprotein particle	Apoc1	IDA		Rat	PMID:16282639|RGD:2313954
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOC1	IDA		Human	PMID:15576844
Cellular Component	GO:0034361	very-low-density lipoprotein particle	Apoc1	IDA		Rat	PMID:16282639|RGD:2313954
Biological Process	GO:0042074	cell migration involved in gastrulation	apoc1	IMP	ZFIN:ZDB-MRPHLNO-140205-7	Zfish	PMID:24203452
Biological Process	GO:0033344	cholesterol efflux	APOC1	IDA		Human	PMID:11162594
Biological Process	GO:0008203	cholesterol metabolic process	Apoc1	IMP	MGI:MGI:2157218	Mouse	PMID:7848292
Biological Process	GO:0034382	chylomicron remnant clearance	APOC1	IDA		Human	PMID:4020294
Biological Process	GO:0032375	negative regulation of cholesterol transport	APOC1	IDA		Human	PMID:10978346
Biological Process	GO:0045717	negative regulation of fatty acid biosynthetic process	APOC1	IDA		Human	PMID:15576844
Biological Process	GO:0050995	negative regulation of lipid catabolic process	APOC1	IDA		Human	PMID:15576844
Biological Process	GO:0045833	negative regulation of lipid metabolic process	APOC1	IDA		Human	PMID:182536
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	APOC1	IDA		Human	PMID:15576844
Biological Process	GO:0010900	negative regulation of phosphatidylcholine catabolic process	APOC1	IDA		Human	PMID:2302419
Biological Process	GO:0048261	negative regulation of receptor-mediated endocytosis	APOC1	IDA		Human	PMID:1917954
Biological Process	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	APOC1	IDA		Human	PMID:1917954
Biological Process	GO:0033700	phospholipid efflux	APOC1	IDA		Human	PMID:11162594
Biological Process	GO:0034369	plasma lipoprotein particle remodeling	APOC1	IDA		Human	PMID:10978346
Biological Process	GO:0032368	regulation of lipid transport	Apoc1	IDA		Rat	PMID:16282639|RGD:2313954
Biological Process	GO:0006641	triglyceride metabolic process	Apoc1	IMP	MGI:MGI:2157218	Mouse	PMID:7848292
Biological Process	GO:0034447	very-low-density lipoprotein particle clearance	APOC1	IGI		Human	PMID:15576844

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern