Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOC2
  • Mouse genes Apoc2
  • Rat genes Apoc2
  • Zfish genes apoc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apoc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0055102	lipase inhibitor activity	APOC2	IDA		Human	PMID:182536
Molecular Function	GO:0008289	lipid binding	APOC2	IDA		Human	PMID:10727238
Molecular Function	GO:0060230	lipoprotein lipase activator activity	APOC2	IDA		Human	PMID:10727238
Molecular Function	GO:0060230	lipoprotein lipase activator activity	APOC2	IDA		Human	PMID:270715
Molecular Function	GO:0140677	molecular function activator activity	APOC2	EXP		Human	PMID:15209504
Molecular Function	GO:0016004	phospholipase activator activity	APOC2	IDA		Human	PMID:10727238
Molecular Function	GO:0043274	phospholipase binding	APOC2	IPI	UniProtKB:P11151	Human	PMID:10727238
Molecular Function	GO:0005515	protein binding	APOC2	IPI	UniProtKB:P49638	Human	PMID:32296183
Cellular Component	GO:0042627	chylomicron	APOC2	IDA		Human	PMID:8245722
Cellular Component	GO:0005615	extracellular space	APOC2	IDA		Human	PMID:10727238
Cellular Component	GO:0034363	intermediate-density lipoprotein particle	APOC2	IDA		Human	PMID:17336988
Cellular Component	GO:0034362	low-density lipoprotein particle	APOC2	IDA		Human	PMID:8245722
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	APOC2	IDA		Human	PMID:16682745
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOC2	IDA		Human	PMID:8245722
Biological Process	GO:0033344	cholesterol efflux	APOC2	IDA		Human	PMID:11162594
Biological Process	GO:0034382	chylomicron remnant clearance	APOC2	IDA		Human	PMID:4020294
Biological Process	GO:0060216	definitive hemopoiesis	apoc2	IMP	ZFIN:ZDB-GENO-190507-1	Zfish	PMID:29615667
Biological Process	GO:0034384	high-density lipoprotein particle clearance	APOC2	IMP		Human	PMID:15778093
Biological Process	GO:0006629	lipid metabolic process	apoc2	IMP	ZFIN:ZDB-MRPHLNO-210401-1	Zfish	PMID:32768193
Biological Process	GO:0042159	lipoprotein catabolic process	apoc2	IMP		Zfish	PMID:22581286
Biological Process	GO:0042953	lipoprotein transport	Apoc2	IDA		Rat	PMID:4020294|RGD:1599181
Biological Process	GO:0032375	negative regulation of cholesterol transport	APOC2	IMP		Human	PMID:15778093
Biological Process	GO:0045833	negative regulation of lipid metabolic process	APOC2	IDA		Human	PMID:182536
Biological Process	GO:0048261	negative regulation of receptor-mediated endocytosis	APOC2	IDA		Human	PMID:1917954
Biological Process	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	APOC2	IDA		Human	PMID:1917954
Biological Process	GO:0033700	phospholipid efflux	APOC2	IDA		Human	PMID:11162594
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	APOC2	IDA		Human	PMID:10727238
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	APOC2	IDA		Human	PMID:10727238
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	APOC2	IDA		Human	PMID:15878877
Biological Process	GO:0010518	positive regulation of phospholipase activity	APOC2	IDA		Human	PMID:10727238
Biological Process	GO:0060697	positive regulation of phospholipid catabolic process	APOC2	IDA		Human	PMID:10727238
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	APOC2	IDA		Human	PMID:10727238
Biological Process	GO:0009410	response to xenobiotic stimulus	Apoc2	IEP		Rat	PMID:9888873|RGD:1599178
Biological Process	GO:0070328	triglyceride homeostasis	APOC2	IMP		Human	PMID:17018885

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern