Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOH
  • Mouse genes Apoh
  • Rat genes Apoh
  • Zfish genes ntd5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apoh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	APOH	IPI	UniProtKB:P02749	Human	PMID:18822289
Molecular Function	GO:0008289	lipid binding	APOH	IDA		Human	PMID:222615
Molecular Function	GO:0008289	lipid binding	Apoh	IDA		Rat	PMID:15581857|RGD:1625336
Molecular Function	GO:0060230	lipoprotein lipase activator activity	APOH	IDA		Human	PMID:7417307
Molecular Function	GO:0005543	phospholipid binding	APOH	IDA		Human	PMID:15486070
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:P00747	Human	PMID:16480936
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:P02776	Human	PMID:19805618
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:P01130	Human	PMID:20223219
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:Q924X6	Human	PMID:20223219
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:P11226	Human	PMID:32759297
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	APOH	IPI	UniProtKB:P08519	Human	PMID:9269765
Cellular Component	GO:0009986	cell surface	APOH	IDA		Human	PMID:16480936
Cellular Component	GO:0009986	cell surface	Apoh	IDA		Rat	PMID:9588860|RGD:10054106
Cellular Component	GO:0042627	chylomicron	APOH	IDA		Human	PMID:222615
Cellular Component	GO:0062023	collagen-containing extracellular matrix	APOH	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	APOH	HDA		Human	PMID:27559042
Cellular Component	GO:0005737	cytoplasm	Apoh	IDA		Rat	PMID:9588860|RGD:10054106
Cellular Component	GO:0070062	extracellular exosome	APOH	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	APOH	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	APOH	IDA		Human	PMID:15486070
Cellular Component	GO:0005615	extracellular space	APOH	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	APOH	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Apoh	IDA		Mouse	PMID:11145969
Cellular Component	GO:0005615	extracellular space	Apoh	IDA		Rat	PMID:7389984|RGD:10054110
Cellular Component	GO:0034364	high-density lipoprotein particle	APOH	IDA		Human	PMID:222615
Cellular Component	GO:0005886	plasma membrane	Apoh	IDA		Rat	PMID:9588860|RGD:10054106
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOH	IDA		Human	PMID:222615
Biological Process	GO:0007568	aging	Apoh	IEP		Rat	PMID:21472381|RGD:5685689
Biological Process	GO:0031100	animal organ regeneration	Apoh	IMP		Rat	PMID:15109573|RGD:1625337
Biological Process	GO:0007596	blood coagulation	Apoh	IMP		Rat	PMID:15956288|RGD:1625334
Biological Process	GO:0007597	blood coagulation, intrinsic pathway	APOH	IDA		Human	PMID:4052628
Biological Process	GO:0016525	negative regulation of angiogenesis	APOH	IDA		Human	PMID:17872974
Biological Process	GO:0030195	negative regulation of blood coagulation	APOH	IDA		Human	PMID:4052628
Biological Process	GO:0010596	negative regulation of endothelial cell migration	APOH	IDA		Human	PMID:17872974
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	APOH	IDA		Human	PMID:17872974
Biological Process	GO:0051918	negative regulation of fibrinolysis	APOH	IDA		Human	PMID:14726399
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	APOH	IDA		Human	PMID:15534879
Biological Process	GO:0060268	negative regulation of respiratory burst	Apoh	IDA		Rat	PMID:12180124|RGD:10054105
Biological Process	GO:0034392	negative regulation of smooth muscle cell apoptotic process	APOH	IDA		Human	PMID:15534879
Biological Process	GO:0031639	plasminogen activation	APOH	IDA		Human	PMID:16480936
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	APOH	IDA		Human	PMID:7417307
Biological Process	GO:0010898	positive regulation of triglyceride catabolic process	Apoh	IDA		Rat	PMID:7078428|RGD:8554677
Biological Process	GO:0030193	regulation of blood coagulation	Apoh	IMP	MGI:MGI:2157224	Mouse	PMID:11145969
Biological Process	GO:0051917	regulation of fibrinolysis	APOH	IDA		Human	PMID:16480936
Biological Process	GO:0034014	response to triglyceride	Apoh	IEP		Rat	PMID:21472381|RGD:5685689
Biological Process	GO:0006641	triglyceride metabolic process	APOH	IDA		Human	PMID:7417307
Biological Process	GO:0034197	triglyceride transport	Apoh	IDA		Rat	PMID:7078428|RGD:8554677

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern