Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOL1,APOL2
  • Mouse genes Apol9b
  • Rat genes Apol9a
  • Zfish genes apol1,si:cabz01007802.1,si:cabz01007807.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apol9b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	APOL1	IDA		Human	PMID:16020735
Molecular Function	GO:0008289	lipid binding	APOL1	IDA		Human	PMID:16020735
Molecular Function	GO:0005515	protein binding	APOL1	IPI	UniProtKB:Q26807	Human	PMID:12621437
Molecular Function	GO:0005515	protein binding	APOL1	IPI	UniProtKB:Q8IXL6	Human	PMID:22582013
Molecular Function	GO:0005515	protein binding	APOL1	IPI	UniProtKB:Q9UJX2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:O00258	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:O00559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:O95377	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:P05107	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q09470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q4KMG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q6PL24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q86UD3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q8IV31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q8TD22	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q8WZ55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q96B21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q96RD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9BXS9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9GZY8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9NVV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9NZ43	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APOL2	IPI	UniProtKB:Q9Y3P8	Human	PMID:32296183
Cellular Component	GO:0072562	blood microparticle	APOL1	HDA		Human	PMID:22516433
Cellular Component	GO:0005615	extracellular space	APOL1	IDA		Human	PMID:17192540
Cellular Component	GO:0034364	high-density lipoprotein particle	APOL1	IDA		Human	PMID:9325276
Cellular Component	GO:0016020	membrane	APOL2	HDA		Human	PMID:19946888
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOL1	IDA		Human	PMID:17154273
Biological Process	GO:1902476	chloride transmembrane transport	APOL1	IDA		Human	PMID:16020735
Biological Process	GO:0051838	cytolysis by host of symbiont cells	APOL1	IDA		Human	PMID:12621437
Biological Process	GO:0051838	cytolysis by host of symbiont cells	APOL1	IDA		Human	PMID:17192540
Biological Process	GO:0003094	glomerular filtration	apol1	IGI	ZFIN:ZDB-MRPHLNO-121120-5,ZFIN:ZDB-MRPHLNO-130110-2,ZFIN:ZDB-MRPHLNO-151006-3	Zfish	PMID:26147622
Biological Process	GO:0003094	glomerular filtration	apol1	IMP	ZFIN:ZDB-MRPHLNO-150311-1	Zfish	PMID:25298528
Biological Process	GO:0003094	glomerular filtration	apol1	IMP	ZFIN:ZDB-MRPHLNO-151006-3	Zfish	PMID:26147622
Biological Process	GO:0032835	glomerulus development	apol1	IMP	ZFIN:ZDB-MRPHLNO-151006-3	Zfish	PMID:26147622
Biological Process	GO:0032835	glomerulus development	apol1	IMP	ZFIN:ZDB-CRISPR-151006-1	Zfish	PMID:26147622
Biological Process	GO:0045087	innate immune response	APOL1	IDA		Human	PMID:17192540
Biological Process	GO:0072015	podocyte development	apol1	IMP	ZFIN:ZDB-CRISPR-151006-1	Zfish	PMID:26147622
Biological Process	GO:0072015	podocyte development	apol1	IMP	ZFIN:ZDB-MRPHLNO-151006-3	Zfish	PMID:26147622
Biological Process	GO:0035775	pronephric glomerulus morphogenesis	apol1	IMP	ZFIN:ZDB-MRPHLNO-171208-1	Zfish	PMID:27138898

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern