Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APRT
  • Mouse genes Aprt
  • Rat genes Aprt
  • Zfish genes aprt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aprt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002055	adenine binding	Aprt	IDA		Mouse	PMID:9218001
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	APRT	IDA		Human	PMID:15196008
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IMP	MGI:MGI:2654615	Mouse	PMID:9776749
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA		Mouse	PMID:6307822
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IMP	MGI:MGI:2429961	Mouse	PMID:8864750
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA		Mouse	PMID:718989
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IMP	MGI:MGI:1857278	Mouse	PMID:8894695
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IMP	MGI:MGI:1857278	Mouse	PMID:8643571
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IMP		Mouse	PMID:8485579
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA		Mouse	PMID:1235912
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IGI	MGI:MGI:96217	Mouse	PMID:8485579
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA		Mouse	PMID:7444718
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA		Mouse	PMID:7323947
Molecular Function	GO:0003999	adenine phosphoribosyltransferase activity	Aprt	IDA		Mouse	PMID:198184
Molecular Function	GO:0016208	AMP binding	APRT	IDA		Human	PMID:15196008
Molecular Function	GO:0016208	AMP binding	Aprt	IDA		Rat	PMID:748918|RGD:1599205
Molecular Function	GO:0005515	protein binding	APRT	IPI	UniProtKB:Q6DKK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	APRT	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Cellular Component	GO:0005829	cytosol	APRT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Aprt	IDA		Mouse	PMID:718989
Cellular Component	GO:0070062	extracellular exosome	APRT	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	APRT	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	APRT	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	APRT	IDA		Human	GO_REF:0000052
Biological Process	GO:0046083	adenine metabolic process	Aprt	IGI	MGI:MGI:96217	Mouse	PMID:8894695
Biological Process	GO:0046083	adenine metabolic process	Aprt	IMP	MGI:MGI:1857278	Mouse	PMID:8643571
Biological Process	GO:0046083	adenine metabolic process	Aprt	IMP	MGI:MGI:1857278	Mouse	PMID:8894695
Biological Process	GO:0044209	AMP salvage	Aprt	IMP	MGI:MGI:2429961	Mouse	PMID:8864750
Biological Process	GO:0044209	AMP salvage	Aprt	IMP	MGI:MGI:2654615	Mouse	PMID:9776749
Biological Process	GO:0044209	AMP salvage	Aprt	IDA		Mouse	PMID:718989
Biological Process	GO:0032869	cellular response to insulin stimulus	Aprt	IEP		Rat	PMID:2185659|RGD:2316798
Biological Process	GO:0032263	GMP salvage	Aprt	IDA		Mouse	PMID:718989
Biological Process	GO:0007625	grooming behavior	Aprt	IGI	MGI:MGI:96217	Mouse	PMID:8485579
Biological Process	GO:0032264	IMP salvage	Aprt	IMP	MGI:MGI:2654615	Mouse	PMID:9776749
Biological Process	GO:0007595	lactation	Aprt	IDA		Rat	PMID:2451510|RGD:1599204
Biological Process	GO:0006166	purine ribonucleoside salvage	Aprt	IMP		Mouse	PMID:8485579
Biological Process	GO:0006166	purine ribonucleoside salvage	Aprt	IGI	MGI:MGI:96217	Mouse	PMID:8485579

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern