Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AQP11
  • Mouse genes Aqp11
  • Rat genes Aqp11
  • Zfish genes aqp11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aqp11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015254	glycerol channel activity	AQP11	IMP		Human	PMID:24845055
Molecular Function	GO:0042802	identical protein binding	Aqp11	IPI	RGD:628763	Rat	PMID:16650285|RGD:2292708
Molecular Function	GO:0015250	water channel activity	AQP11	IMP		Human	PMID:24845055
Molecular Function	GO:0015250	water channel activity	AQP11	IDA		Human	PMID:24918044
Molecular Function	GO:0015250	water channel activity	Aqp11	IDA		Mouse	MGI:MGI:6368082|PMID:21251984
Molecular Function	GO:0015250	water channel activity	Aqp11	IDA		Mouse	PMID:17178102
Cellular Component	GO:0009986	cell surface	AQP11	IDA		Human	PMID:16650285
Cellular Component	GO:0009986	cell surface	Aqp11	IDA		Rat	PMID:16650285|RGD:2292708
Cellular Component	GO:0005737	cytoplasm	Aqp11	IDA		Mouse	PMID:16107722
Cellular Component	GO:0005829	cytosol	AQP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Aqp11	IDA		Rat	PMID:16650285|RGD:2292708
Cellular Component	GO:0030425	dendrite	Aqp11	IDA		Rat	PMID:16650285|RGD:2292708
Cellular Component	GO:0005783	endoplasmic reticulum	AQP11	IDA		Human	PMID:24918044
Cellular Component	GO:0005783	endoplasmic reticulum	AQP11	IDA		Human	PMID:31546170
Cellular Component	GO:0005783	endoplasmic reticulum	Aqp11	IDA		Mouse	MGI:MGI:6368076|PMID:21118806
Cellular Component	GO:0005783	endoplasmic reticulum	Aqp11	IMP		Mouse	MGI:MGI:5698795|PMID:24854278
Cellular Component	GO:0005783	endoplasmic reticulum	Aqp11	IDA		Mouse	PMID:16107722
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	AQP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Aqp11	IDA		Mouse	MGI:MGI:3588799|PMID:16107722
Cellular Component	GO:0005886	plasma membrane	AQP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	AQP11	IDA		Human	PMID:31546170
Cellular Component	GO:0005886	plasma membrane	Aqp11	IDA		Mouse	MGI:MGI:6368076|PMID:21118806
Cellular Component	GO:0005886	plasma membrane	Aqp11	IDA		Rat	PMID:16650285|RGD:2292708
Biological Process	GO:0048388	endosomal lumen acidification	Aqp11	IMP	MGI:MGI:3528447	Mouse	PMID:16107722
Biological Process	GO:0015793	glycerol transmembrane transport	AQP11	IMP		Human	PMID:24845055
Biological Process	GO:0080170	hydrogen peroxide transmembrane transport	AQP11	IMP		Human	PMID:31546170
Biological Process	GO:0032364	intracellular oxygen homeostasis	Aqp11	IMP		Mouse	MGI:MGI:6377720|PMID:30656220
Biological Process	GO:0009992	intracellular water homeostasis	AQP11	IMP		Human	PMID:24845055
Biological Process	GO:0009992	intracellular water homeostasis	AQP11	IDA		Human	PMID:24918044
Biological Process	GO:0009992	intracellular water homeostasis	Aqp11	IDA		Mouse	MGI:MGI:6368076|PMID:21118806
Biological Process	GO:0009992	intracellular water homeostasis	Aqp11	IDA		Mouse	MGI:MGI:6368082|PMID:21251984
Biological Process	GO:0001822	kidney development	Aqp11	IMP	MGI:MGI:3528447	Mouse	PMID:16107722
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Aqp11	IMP		Mouse	MGI:MGI:6367451|PMID:27582095
Biological Process	GO:1904293	negative regulation of ERAD pathway	Aqp11	IMP		Mouse	MGI:MGI:3813160|PMID:18606867
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	Aqp11	IMP		Mouse	MGI:MGI:3813160|PMID:18606867
Biological Process	GO:0008284	positive regulation of cell population proliferation	AQP11	IMP		Human	PMID:30563120
Biological Process	GO:0006486	protein glycosylation	Aqp11	IMP		Mouse	MGI:MGI:5698795|PMID:24854278
Biological Process	GO:0051260	protein homooligomerization	AQP11	IDA		Human	PMID:24918044
Biological Process	GO:0051260	protein homooligomerization	AQP11	IDA		Human	PMID:31546170
Biological Process	GO:0051260	protein homooligomerization	Aqp11	IDA		Mouse	MGI:MGI:6368076|PMID:21118806
Biological Process	GO:0006612	protein targeting to membrane	Aqp11	IMP		Mouse	MGI:MGI:5698795|PMID:24854278
Biological Process	GO:0072014	proximal tubule development	Aqp11	IMP		Mouse	MGI:MGI:6367451|PMID:27582095
Biological Process	GO:0072014	proximal tubule development	Aqp11	IMP	MGI:MGI:1889609	Mouse	PMID:18701606
Biological Process	GO:0006833	water transport	AQP11	IMP		Human	PMID:24845055
Biological Process	GO:0006833	water transport	Aqp11	IDA		Mouse	PMID:17178102

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern