Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AQP5
  • Mouse genes Aqp5
  • Rat genes Aqp5
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aqp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	AQP5	IPI	UniProtKB:P55064	Human	PMID:18768791
Molecular Function	GO:0005515	protein binding	AQP5	IPI	UniProtKB:Q99750	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AQP5	IPI	UniProtKB:Q99750	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	AQP5	IPI	UniProtKB:P61978	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AQP5	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AQP5	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AQP5	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Aqp5	IPI	PR:P02816	Mouse	PMID:18696337
Molecular Function	GO:0005515	protein binding	Aqp5	IPI	PR:P11590	Mouse	PMID:18696337
Molecular Function	GO:0015250	water channel activity	AQP5	IDA		Human	PMID:12801959
Molecular Function	GO:0015250	water channel activity	AQP5	IDA		Human	PMID:18768791
Cellular Component	GO:0016324	apical plasma membrane	AQP5	IDA		Human	PMID:12801959
Cellular Component	GO:0016324	apical plasma membrane	Aqp5	IDA		Mouse	PMID:18696337
Cellular Component	GO:0016324	apical plasma membrane	Aqp5	IDA		Mouse	PMID:11707570
Cellular Component	GO:0016324	apical plasma membrane	Aqp5	IDA		Rat	PMID:11773623|RGD:70240
Cellular Component	GO:0016324	apical plasma membrane	Aqp5	IDA		Rat	PMID:12703553|RGD:2306444
Cellular Component	GO:0009925	basal plasma membrane	Aqp5	IDA		Mouse	PMID:12042359
Cellular Component	GO:0009925	basal plasma membrane	Aqp5	IDA		Mouse	PMID:11707570
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	AQP5	IDA		Human	PMID:26569106
Cellular Component	GO:0005783	endoplasmic reticulum	Aqp5	IDA		Mouse	PMID:16107722
Cellular Component	GO:0070062	extracellular exosome	AQP5	HDA		Human	PMID:19199708
Cellular Component	GO:0005902	microvillus	Aqp5	IDA		Mouse	PMID:11707570
Cellular Component	GO:0005886	plasma membrane	AQP5	IDA		Human	PMID:26569106
Cellular Component	GO:0005886	plasma membrane	Aqp5	IDA		Mouse	PMID:11891232
Cellular Component	GO:0005886	plasma membrane	Aqp5	IDA		Mouse	PMID:12042359
Biological Process	GO:0048593	camera-type eye morphogenesis	Aqp5	IMP	MGI:MGI:2150059	Mouse	PMID:11891232
Biological Process	GO:0015670	carbon dioxide transport	AQP5	IDA		Human	PMID:19273840
Biological Process	GO:0015670	carbon dioxide transport	Aqp5	IDA		Rat	PMID:19273840|RGD:8553588
Biological Process	GO:0071476	cellular hypotonic response	AQP5	IDA		Human	PMID:26569106
Biological Process	GO:0042476	odontogenesis	AQP5	IEP		Human	PMID:12522663
Biological Process	GO:0030157	pancreatic juice secretion	AQP5	IEP		Human	PMID:12801959
Biological Process	GO:0051289	protein homotetramerization	AQP5	IDA		Human	PMID:18768791
Biological Process	GO:0051289	protein homotetramerization	AQP5	IDA		Human	PMID:26569106
Biological Process	GO:0046541	saliva secretion	Aqp5	IMP	MGI:MGI:2150059	Mouse	PMID:10400615
Biological Process	GO:0046541	saliva secretion	Aqp5	IMP	MGI:MGI:2150059	Mouse	PMID:10795927
Biological Process	GO:0046541	saliva secretion	Aqp5	IMP	MGI:MGI:2150059	Mouse	PMID:15647389
Biological Process	GO:0006833	water transport	AQP5	IDA		Human	PMID:18768791
Biological Process	GO:0006833	water transport	Aqp5	IMP	MGI:MGI:2150059	Mouse	PMID:15557451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern