Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARC
  • Mouse genes Arc
  • Rat genes Arc
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Arc	IDA		Rat	PMID:29328916|RGD:13514080
Molecular Function	GO:0005515	protein binding	ARC	IPI	UniProtKB:O95935	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARC	IPI	UniProtKB:P25815	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARC	IPI	UniProtKB:Q16527	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARC	IPI	UniProtKB:Q9H788	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:6092779|PMID:28671696
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:5474131|PMID:23424281
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:P28652	Mouse	MGI:MGI:5431161|PMID:22579289
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:P49769:PRO_0000025597	Mouse	MGI:MGI:5299950|PMID:22036569
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:4359331|PMID:19455133
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:P49768:PRO_0000025591	Rat	PMID:22036569|RGD:8554064
Molecular Function	GO:0005515	protein binding	Arc	IPI	UniProtKB:P08413	Rat	PMID:22579289|RGD:8553506
Cellular Component	GO:0015629	actin cytoskeleton	Arc	IDA		Rat	PMID:7857651|RGD:61538
Cellular Component	GO:0005737	cytoplasm	ARC	IDA		Human	PMID:21834987
Cellular Component	GO:0030425	dendrite	Arc	IDA		Mouse	PMID:23936366
Cellular Component	GO:0043197	dendritic spine	Arc	IDA		Mouse	MGI:MGI:6316437|PMID:31151856
Cellular Component	GO:1903561	extracellular vesicle	Arc	IDA		Rat	PMID:29328916|RGD:13514080
Cellular Component	GO:0098978	glutamatergic synapse	Arc	IMP		Mouse	PMID:17088211
Cellular Component	GO:0098978	glutamatergic synapse	Arc	IDA		Mouse	PMID:17088211
Cellular Component	GO:0098978	glutamatergic synapse	Arc	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098978	glutamatergic synapse	Arc	IMP		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0045121	membrane raft	Arc	IDA		Mouse	MGI:MGI:6148485|PMID:29264923
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	Arc	IDA		Mouse	PMID:23936366
Cellular Component	GO:0005886	plasma membrane	ARC	IDA		Human	PMID:21834987
Cellular Component	GO:0098839	postsynaptic density membrane	Arc	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098839	postsynaptic density membrane	Arc	IMP		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098845	postsynaptic endosome	Arc	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098845	postsynaptic endosome	Arc	IMP		Rat	PMID:17088211|RGD:10047209
Biological Process	GO:0009952	anterior/posterior pattern specification	Arc	IMP	MGI:MGI:2386454	Mouse	PMID:10727859
Biological Process	GO:0016477	cell migration	ARC	IMP		Human	PMID:21834987
Biological Process	GO:0007010	cytoskeleton organization	ARC	IMP		Human	PMID:21834987
Biological Process	GO:0007492	endoderm development	Arc	IMP	MGI:MGI:2386454	Mouse	PMID:10727859
Biological Process	GO:0007612	learning	Arc	IEP		Rat	PMID:20111591|RGD:2317921
Biological Process	GO:0007616	long-term memory	Arc	IMP		Mouse	MGI:MGI:6316437|PMID:31151856
Biological Process	GO:0007616	long-term memory	Arc	IMP		Rat	PMID:10818134|RGD:13514089
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Arc	IMP		Mouse	MGI:MGI:6316437|PMID:31151856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Arc	IDA		Rat	PMID:17898216|RGD:12793056
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Arc	IMP		Rat	PMID:17898216|RGD:12793056
Biological Process	GO:0051028	mRNA transport	Arc	IDA		Rat	PMID:29328916|RGD:13514080
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	Arc	IMP		Rat	PMID:17088211|RGD:10047209
Biological Process	GO:0051260	protein homooligomerization	Arc	IDA		Rat	PMID:29328916|RGD:13514080
Biological Process	GO:0022604	regulation of cell morphogenesis	ARC	IMP		Human	PMID:21834987
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	Arc	IGI	ComplexPortal:CPX-1134	Rat	PMID:15537891|RGD:13210528
Biological Process	GO:1900452	regulation of long-term synaptic depression	Arc	IDA		Mouse	MGI:MGI:6148485|PMID:29264923
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	Arc	IMP		Mouse	MGI:MGI:6316437|PMID:31151856
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	Arc	IMP		Rat	PMID:10818134|RGD:13514089
Biological Process	GO:1900271	regulation of long-term synaptic potentiation	Arc	IMP		Rat	PMID:17898216|RGD:12793056
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Arc	IEP		Rat	PMID:7857651|RGD:61538
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Arc	IMP		Mouse	PMID:17088211
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Arc	IDA		Mouse	PMID:17088211
Biological Process	GO:0110077	vesicle-mediated intercellular transport	Arc	IDA		Rat	PMID:29328916|RGD:13514080

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern