Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARFGEF1
  • Mouse genes Arfgef1
  • Rat genes Arfgef1
  • Zfish genes arfgef1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arfgef1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARFGEF1	IDA		Human	PMID:15644318
Molecular Function	GO:0017022	myosin binding	ARFGEF1	IPI	UniProtKB:B2RTY4	Human	PMID:15644318
Molecular Function	GO:0017022	myosin binding	ARFGEF1	IPI	UniProtKB:Q13459	Human	PMID:15644318
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q9Y6D5	Human	PMID:10716990
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q13459-2	Human	PMID:15644318
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:P55160	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q99417	Human	PMID:16866877
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:P19338	Human	PMID:18292223
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q7Z4S6	Human	PMID:19020088
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q7Z4S6-2	Human	PMID:19020088
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q14432	Human	PMID:19332778
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q9Y6D5	Human	PMID:19332778
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q8K3E7	Human	PMID:19651892
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q14678	Human	PMID:22084092
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q7Z4S6	Human	PMID:22084092
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q9Y6D5	Human	PMID:22084092
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q8WUA7	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	ARFGEF1	IPI	UniProtKB:Q9NU19	Human	PMID:23572552
Molecular Function	GO:0005515	protein binding	Arfgef1	IPI	RGD:3146	Rat	PMID:15644318|RGD:1579801
Molecular Function	GO:0005515	protein binding	Arfgef1	IPI	UniProtKB:Q63358	Rat	PMID:15644318|RGD:1579801
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	ARFGEF1	IDA		Human	PMID:12571360
Cellular Component	GO:0005829	cytosol	ARFGEF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ARFGEF1	IDA		Human	PMID:10716990
Cellular Component	GO:0005794	Golgi apparatus	ARFGEF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000139	Golgi membrane	ARFGEF1	IDA		Human	PMID:10716990
Cellular Component	GO:0005730	nucleolus	ARFGEF1	IDA		Human	PMID:14973189
Cellular Component	GO:0005654	nucleoplasm	ARFGEF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ARFGEF1	IDA		Human	PMID:22084092
Cellular Component	GO:0030532	small nuclear ribonucleoprotein complex	ARFGEF1	IDA		Human	PMID:18292223
Cellular Component	GO:0005802	trans-Golgi network	Arfgef1	IDA		Rat	PMID:11809827|RGD:2316366
Biological Process	GO:0010256	endomembrane system organization	ARFGEF1	IMP		Human	PMID:20360857
Biological Process	GO:0007030	Golgi organization	ARFGEF1	IMP		Human	PMID:17227842
Biological Process	GO:0007030	Golgi organization	ARFGEF1	IMP		Human	PMID:20360857
Biological Process	GO:0030837	negative regulation of actin filament polymerization	ARFGEF1	IMP		Human	PMID:22084092
Biological Process	GO:0034260	negative regulation of GTPase activity	ARFGEF1	IDA		Human	PMID:15644318
Biological Process	GO:0031175	neuron projection development	Arfgef1	IMP		Rat	PMID:24090963|RGD:10047159
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Arfgef1	IMP		Rat	PMID:24090963|RGD:10047159
Biological Process	GO:0090303	positive regulation of wound healing	ARFGEF1	IMP		Human	PMID:22084092
Biological Process	GO:0006486	protein glycosylation	ARFGEF1	IMP		Human	PMID:17227842
Biological Process	GO:2000114	regulation of establishment of cell polarity	ARFGEF1	IMP		Human	PMID:22084092

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern