Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARG1
  • Mouse genes Arg1
  • Rat genes Arg1
  • Zfish genes arg1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arg1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004053	arginase activity	Arg1	IDA		Mouse	PMID:9502196
Molecular Function	GO:0004053	arginase activity	Arg1	IDA		Rat	PMID:12069499|RGD:634666
Molecular Function	GO:0004053	arginase activity	Arg1	IDA		Rat	PMID:4062872|RGD:2300098
Molecular Function	GO:0042802	identical protein binding	Arg1	IPI	RGD:2150	Rat	PMID:1569574|RGD:4142823
Molecular Function	GO:0030145	manganese ion binding	Arg1	IDA		Rat	PMID:12820884|RGD:4142797
Molecular Function	GO:0005515	protein binding	ARG1	IPI	UniProtKB:Q9NX76	Human	PMID:28813417
Cellular Component	GO:0005737	cytoplasm	Arg1	IDA		Rat	PMID:11931836|RGD:1626298
Cellular Component	GO:0005737	cytoplasm	Arg1	IDA		Rat	PMID:22023808|RGD:153297778
Cellular Component	GO:0005737	cytoplasm	Arg1	IDA		Rat	PMID:29504286|RGD:152995491
Cellular Component	GO:0005615	extracellular space	ARG1	IDA		Human	PMID:16709924
Cellular Component	GO:0005615	extracellular space	Arg1	IDA		Rat	PMID:16872590|RGD:1599211
Cellular Component	GO:0005741	mitochondrial outer membrane	Arg1	IDA		Rat	PMID:15753084|RGD:8693655
Cellular Component	GO:0043005	neuron projection	Arg1	IDA		Rat	PMID:16914676|RGD:4143186
Cellular Component	GO:0043025	neuronal cell body	Arg1	IDA		Rat	PMID:16914676|RGD:4143186
Cellular Component	GO:0005634	nucleus	ARG1	HDA		Human	PMID:21630459
Biological Process	GO:0007568	aging	Arg1	IEP		Rat	PMID:17704205|RGD:8693646
Biological Process	GO:0019547	arginine catabolic process to ornithine	Arg1	IDA		Rat	PMID:15753084|RGD:8693655
Biological Process	GO:0006525	arginine metabolic process	Arg1	IDA		Rat	PMID:4062872|RGD:2300098
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Arg1	IEP		Rat	PMID:11250887|RGD:4144048
Biological Process	GO:0071377	cellular response to glucagon stimulus	Arg1	IEP		Rat	PMID:8460937|RGD:4140437
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Arg1	IEP		Rat	PMID:18001708|RGD:4142843
Biological Process	GO:0071353	cellular response to interleukin-4	Arg1	IEP		Rat	PMID:14618299|RGD:4144042
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Arg1	IEP		Rat	PMID:9013624|RGD:4144055
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Arg1	IEP		Rat	PMID:12069499|RGD:634666
Biological Process	GO:0032964	collagen biosynthetic process	Arg1	IMP		Rat	PMID:20107769|RGD:4143276
Biological Process	GO:0042832	defense response to protozoan	Arg1	IMP		Mouse	MGI:MGI:5908339|PMID:19360123
Biological Process	GO:0007565	female pregnancy	Arg1	IEP		Rat	PMID:7649538|RGD:1599208
Biological Process	GO:0001889	liver development	Arg1	IEP		Rat	PMID:8690412|RGD:4144072
Biological Process	GO:0030324	lung development	Arg1	IEP		Rat	PMID:18192591|RGD:4143284
Biological Process	GO:0060056	mammary gland involution	Arg1	IEP		Rat	PMID:20110414|RGD:4142798
Biological Process	GO:0060135	maternal process involved in female pregnancy	Arg1	IEP		Rat	PMID:16735458|RGD:4143426
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	Arg1	IMP		Mouse	MGI:MGI:5908339|PMID:19360123
Biological Process	GO:0042130	negative regulation of T cell proliferation	ARG1	IDA		Human	PMID:16709924
Biological Process	GO:2000552	negative regulation of T-helper 2 cell cytokine production	Arg1	IMP		Mouse	MGI:MGI:5908339|PMID:19360123
Biological Process	GO:0060336	negative regulation of type II interferon-mediated signaling pathway	ARG1	IMP		Human	PMID:16709924
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Arg1	IDA		Rat	PMID:11742824|RGD:4144047
Biological Process	GO:0070965	positive regulation of neutrophil mediated killing of fungus	ARG1	IMP		Human	PMID:15546957
Biological Process	GO:1905541	regulation of L-arginine import across plasma membrane	Arg1	IDA		Rat	PMID:11120661|RGD:4144049
Biological Process	GO:0014075	response to amine	Arg1	IEP		Rat	PMID:16459053|RGD:4143195
Biological Process	GO:0043200	response to amino acid	Arg1	IEP		Rat	PMID:15458774|RGD:4143261
Biological Process	GO:0048678	response to axon injury	Arg1	IEP		Rat	PMID:15735325|RGD:4143237
Biological Process	GO:0046686	response to cadmium ion	Arg1	IEP		Rat	PMID:16570515|RGD:4143188
Biological Process	GO:0009635	response to herbicide	Arg1	IEP		Rat	PMID:20388547|RGD:2317876
Biological Process	GO:0032496	response to lipopolysaccharide	Arg1	IEP		Rat	PMID:10652239|RGD:1599265
Biological Process	GO:0032496	response to lipopolysaccharide	Arg1	IEP		Rat	PMID:9686345|RGD:4139908
Biological Process	GO:0010042	response to manganese ion	Arg1	IEP		Rat	PMID:15564441|RGD:4143239
Biological Process	GO:0051597	response to methylmercury	Arg1	IEP		Rat	PMID:18488197|RGD:4142824
Biological Process	GO:0043434	response to peptide hormone	Arg1	IEP		Rat	PMID:19386725|RGD:4142801
Biological Process	GO:0010269	response to selenium ion	Arg1	IEP		Rat	PMID:14624471|RGD:4143267
Biological Process	GO:0048545	response to steroid hormone	Arg1	IEP		Rat	PMID:9688877|RGD:1599313
Biological Process	GO:0033189	response to vitamin A	Arg1	IEP		Rat	PMID:18271400|RGD:4142841
Biological Process	GO:0033197	response to vitamin E	Arg1	IEP		Rat	PMID:14624471|RGD:4143267
Biological Process	GO:0009611	response to wounding	Arg1	IEP		Rat	PMID:12069499|RGD:634666
Biological Process	GO:0009410	response to xenobiotic stimulus	Arg1	IEP		Rat	PMID:15888029|RGD:4143232
Biological Process	GO:0010043	response to zinc ion	Arg1	IEP		Rat	PMID:11686772|RGD:4140931
Biological Process	GO:0000050	urea cycle	Arg1	IDA		Rat	PMID:4062872|RGD:2300098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern