Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP1
  • Mouse genes Arhgap1
  • Rat genes Arhgap1
  • Zfish genes arhgap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ARHGAP1	HDA		Human	PMID:25468996
Molecular Function	GO:0005096	GTPase activator activity	ARHGAP1	IDA		Human	PMID:8253717
Molecular Function	GO:0005096	GTPase activator activity	ARHGAP1	IDA		Human	PMID:8288572
Molecular Function	GO:0005096	GTPase activator activity	Arhgap1	IDA		Mouse	PMID:10699171
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:P61586	Human	PMID:11927263
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:Q7Z465	Human	PMID:12901880
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:P61586	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:P61586	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:Q99961	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:P60953-2	Human	PMID:9262406
Molecular Function	GO:0005515	protein binding	ARHGAP1	IPI	UniProtKB:P60953-2	Human	PMID:9846874
Molecular Function	GO:0005515	protein binding	Arhgap1	IPI	PR:Q9ERR1	Mouse	PMID:18331715
Molecular Function	GO:0031267	small GTPase binding	ARHGAP1	IPI	UniProtKB:P62490	Human	PMID:16380373
Cellular Component	GO:0031252	cell leading edge	Arhgap1	IDA		Mouse	PMID:18331715
Cellular Component	GO:0005737	cytoplasm	ARHGAP1	IDA		Human	PMID:25468996
Cellular Component	GO:0010008	endosome membrane	ARHGAP1	IDA		Human	PMID:16380373
Cellular Component	GO:0070062	extracellular exosome	ARHGAP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ARHGAP1	HDA		Human	PMID:23533145
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ARHGAP1	IDA		Human	PMID:16380373
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Arhgap1	IDA		Rat	PMID:10792618|RGD:10047398
Cellular Component	GO:0005886	plasma membrane	Arhgap1	IDA		Mouse	PMID:15860730
Cellular Component	GO:0001726	ruffle	Arhgap1	IDA		Mouse	PMID:15860730
Cellular Component	GO:0097443	sorting endosome	ARHGAP1	IMP		Human	PMID:16380373
Biological Process	GO:0016197	endosomal transport	ARHGAP1	IMP		Human	PMID:16380373
Biological Process	GO:2001136	negative regulation of endocytic recycling	ARHGAP1	IMP		Human	PMID:16380373
Biological Process	GO:0043087	regulation of GTPase activity	Arhgap1	IDA		Mouse	PMID:10699171
Biological Process	GO:0007264	small GTPase mediated signal transduction	ARHGAP1	IDA		Human	PMID:8253717
Biological Process	GO:0007264	small GTPase mediated signal transduction	ARHGAP1	IDA		Human	PMID:8288572
Biological Process	GO:0033572	transferrin transport	ARHGAP1	IMP		Human	PMID:16380373

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern