Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP21
  • Mouse genes Arhgap21
  • Rat genes Arhgap21
  • Zfish genes arhgap21a,arhgap21b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARHGAP21	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	ARHGAP21	IPI	UniProtKB:P84078	Human	PMID:17347647
Molecular Function	GO:0005515	protein binding	ARHGAP21	IPI	UniProtKB:P29692	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ARHGAP21	IPI	UniProtKB:P63104	Human	PMID:28514442
Cellular Component	GO:0015629	actin cytoskeleton	ARHGAP21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030054	cell junction	ARHGAP21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	ARHGAP21	IDA		Human	PMID:20525016
Cellular Component	GO:0005886	plasma membrane	ARHGAP21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Arhgap21	IDA		Mouse	PMID:24792215
Biological Process	GO:0051683	establishment of Golgi localization	ARHGAP21	IDA		Human	PMID:20525016
Biological Process	GO:0007030	Golgi organization	ARHGAP21	IMP		Human	PMID:20525016
Biological Process	GO:0051684	maintenance of Golgi location	ARHGAP21	IMP		Human	PMID:20525016
Biological Process	GO:0072384	organelle transport along microtubule	ARHGAP21	IMP		Human	PMID:20525016
Biological Process	GO:0030100	regulation of endocytosis	Arhgap21	IMP		Mouse	PMID:24792215

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern