Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP35
  • Mouse genes Arhgap35
  • Rat genes Arhgap35
  • Zfish genes arhgap35a,arhgap35b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap35

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032794	GTPase activating protein binding	Arhgap35	IPI	RGD:3537	Rat	PMID:2005883|RGD:10002731
Molecular Function	GO:0005096	GTPase activator activity	ARHGAP35	IDA		Human	PMID:19673492
Molecular Function	GO:0005096	GTPase activator activity	Arhgap35	IDA		Mouse	MGI:MGI:3803424|PMID:18502760
Molecular Function	GO:0005096	GTPase activator activity	Arhgap35	IDA		Rat	PMID:9852136|RGD:11535110
Molecular Function	GO:0005543	phospholipid binding	ARHGAP35	IDA		Human	PMID:19673492
Molecular Function	GO:0044877	protein-containing complex binding	Arhgap35	IDA		Rat	PMID:2005883|RGD:10002731
Cellular Component	GO:0015629	actin cytoskeleton	Arhgap35	IDA		Mouse	PMID:11044403
Cellular Component	GO:0036064	ciliary basal body	Arhgap35	IDA		Mouse	MGI:MGI:5776638|PMID:26859289
Cellular Component	GO:0005737	cytoplasm	Arhgap35	IDA		Mouse	PMID:11044403
Cellular Component	GO:0005829	cytosol	Arhgap35	IDA		Rat	PMID:2005883|RGD:10002731
Biological Process	GO:0007411	axon guidance	Arhgap35	IDA		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0007413	axonal fasciculation	Arhgap35	IMP		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0043010	camera-type eye development	Arhgap35	IMP	MGI:MGI:2448591	Mouse	PMID:11044403
Biological Process	GO:0016477	cell migration	Arhgap35	IMP		Mouse	MGI:MGI:3803424|PMID:18502760
Biological Process	GO:0031668	cellular response to extracellular stimulus	Arhgap35	IMP		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0021955	central nervous system neuron axonogenesis	Arhgap35	IMP		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	Arhgap35	IMP		Mouse	MGI:MGI:3803424|PMID:18502760
Biological Process	GO:0030900	forebrain development	Arhgap35	IMP	MGI:MGI:2448591	Mouse	PMID:11044403
Biological Process	GO:0030879	mammary gland development	Arhgap35	IMP		Mouse	MGI:MGI:5298449|PMID:21945077
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Arhgap35	IGI	MGI:MGI:87860	Mouse	PMID:22357865
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Arhgap35	IDA		Mouse	PMID:15084284
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Arhgap35	IGI	MGI:MGI:96602	Mouse	PMID:23595732
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Arhgap35	IGI	MGI:MGI:96610	Mouse	PMID:22357865
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Arhgap35	IGI	MGI:MGI:87860	Mouse	PMID:23595732
Biological Process	GO:0043116	negative regulation of vascular permeability	Arhgap35	IMP		Mouse	PMID:17562701
Biological Process	GO:0001843	neural tube closure	Arhgap35	IMP	MGI:MGI:2448591	Mouse	PMID:11044403
Biological Process	GO:0097485	neuron projection guidance	Arhgap35	IMP		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0045724	positive regulation of cilium assembly	Arhgap35	IMP		Mouse	MGI:MGI:5776638|PMID:26859289
Biological Process	GO:0043547	positive regulation of GTPase activity	Arhgap35	IDA		Rat	PMID:9852136|RGD:11535110
Biological Process	GO:0010976	positive regulation of neuron projection development	Arhgap35	IMP		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0010976	positive regulation of neuron projection development	Arhgap35	IGI	MGI:MGI:87860	Mouse	PMID:15084284
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Arhgap35	IMP		Mouse	MGI:MGI:3803424|PMID:18502760
Biological Process	GO:0008064	regulation of actin polymerization or depolymerization	Arhgap35	IMP		Mouse	MGI:MGI:5776638|PMID:26859289
Biological Process	GO:0050770	regulation of axonogenesis	Arhgap35	IMP		Mouse	MGI:MGI:1933687|PMID:11283609
Biological Process	GO:0008360	regulation of cell shape	Arhgap35	IDA		Mouse	PMID:11044403
Biological Process	GO:0007266	Rho protein signal transduction	Arhgap35	IGI	MGI:MGI:96602	Mouse	PMID:23595732
Biological Process	GO:0007266	Rho protein signal transduction	Arhgap35	IGI	MGI:MGI:87860	Mouse	PMID:23595732
Biological Process	GO:0044319	wound healing, spreading of cells	Arhgap35	IMP		Mouse	MGI:MGI:3803424|PMID:18502760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern