Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP4
  • Mouse genes Arhgap4
  • Rat genes Arhgap4
  • Zfish genes arhgap4a,arhgap4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	Arhgap4	IDA		Rat	PMID:12414125|RGD:632235
Molecular Function	GO:0005515	protein binding	ARHGAP4	IPI	UniProtKB:P55160	Human	PMID:16417406
Cellular Component	GO:0005737	cytoplasm	ARHGAP4	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005737	cytoplasm	Arhgap4	IDA		Rat	PMID:17804252|RGD:2313143
Cellular Component	GO:0005829	cytosol	ARHGAP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	Arhgap4	IDA		Rat	PMID:12414125|RGD:632235
Cellular Component	GO:0030426	growth cone	Arhgap4	IDA		Rat	PMID:17804252|RGD:2313143
Cellular Component	GO:0005874	microtubule	Arhgap4	IDA		Rat	PMID:12414125|RGD:632235
Cellular Component	GO:0005654	nucleoplasm	ARHGAP4	IDA		Human	GO_REF:0000052
Biological Process	GO:0030517	negative regulation of axon extension	Arhgap4	IMP		Rat	PMID:17804252|RGD:2313143
Biological Process	GO:0010764	negative regulation of fibroblast migration	Arhgap4	IMP		Rat	PMID:17804252|RGD:2313143
Biological Process	GO:0007399	nervous system development	Arhgap4	IEP		Rat	PMID:12414125|RGD:632235

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern