Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGDIA
  • Mouse genes Arhgdia
  • Rat genes Arhgdia
  • Zfish genes arhgdia
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgdia

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005504	fatty acid binding	Arhgdia	IDA		Rat	PMID:18084788|RGD:5132873
Molecular Function	GO:0051879	Hsp90 protein binding	Arhgdia	IDA		Rat	PMID:19910677|RGD:9684974
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P61586	Human	PMID:10489445
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P63000	Human	PMID:11513578
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P63000	Human	PMID:17245428
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P61586	Human	PMID:20711218
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P60953	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P60953	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P63000	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P63000	Human	PMID:22157745
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P61586	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:Q63ZY3	Human	PMID:25961457
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P63000	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:Q9NS68	Human	PMID:30337686
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P60953	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ARHGDIA	IPI	UniProtKB:P63000	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Arhgdia	IPI	UniProtKB:Q9QY40	Mouse	MGI:MGI:5532914|PMID:20696765
Molecular Function	GO:0005515	protein binding	Arhgdia	IPI	UniProtKB:P60764	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Arhgdia	IPI	PR:A2AD83	Mouse	PMID:23967341
Molecular Function	GO:0005515	protein binding	Arhgdia	IPI	UniProtKB:Q6RUV5	Rat	PMID:20696765|RGD:8554409
Molecular Function	GO:0005515	protein binding	Arhgdia	IPI	RGD:619755	Rat	PMID:22564631|RGD:9684983
Molecular Function	GO:0005515	protein binding	Arhgdia	IPI	UniProtKB:D3ZD05	Rat	PMID:25961457|RGD:13792518
Molecular Function	GO:0019901	protein kinase binding	Arhgdia	IDA		Rat	PMID:9447972|RGD:9684982
Molecular Function	GO:0005094	Rho GDP-dissociation inhibitor activity	Arhgdia	IDA		Mouse	PMID:15093731
Molecular Function	GO:0031267	small GTPase binding	Arhgdia	IPI	RGD:619921	Rat	PMID:17379756|RGD:1642962
Cellular Component	GO:0005829	cytosol	Arhgdia	IDA		Rat	PMID:9665834|RGD:9684967
Cellular Component	GO:0070062	extracellular exosome	ARHGDIA	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ARHGDIA	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ARHGDIA	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Arhgdia	IDA		Rat	PMID:23633624|RGD:9684969
Cellular Component	GO:0001772	immunological synapse	Arhgdia	IDA		Mouse	PMID:11728336
Cellular Component	GO:0016020	membrane	Arhgdia	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0016020	membrane	Arhgdia	IDA		Rat	PMID:9665834|RGD:9684967
Cellular Component	GO:0005634	nucleus	Arhgdia	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Arhgdia	IDA		Mouse	PMID:18829665
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Arhgdia	IMP		Mouse	PMID:18829665
Cellular Component	GO:0045202	synapse	Arhgdia	EXP		Rat	PMID:24876496|RGD:10047219
Cellular Component	GO:0045202	synapse	Arhgdia	IDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0071260	cellular response to mechanical stimulus	Arhgdia	IMP		Rat	PMID:18566890|RGD:9684962
Biological Process	GO:0071407	cellular response to organic cyclic compound	Arhgdia	IEP		Rat	PMID:22960606|RGD:9684960
Biological Process	GO:0071461	cellular response to redox state	Arhgdia	IEP		Rat	PMID:9665834|RGD:9684967
Biological Process	GO:0030336	negative regulation of cell migration	Arhgdia	IMP		Rat	PMID:20696765|RGD:8554409
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	ARHGDIA	IMP		Human	PMID:8262133
Biological Process	GO:0008360	regulation of cell shape	Arhgdia	IMP		Rat	PMID:23012358|RGD:9684980
Biological Process	GO:0032880	regulation of protein localization	Arhgdia	IDA		Mouse	PMID:8939998
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ARHGDIA	IMP		Human	PMID:8262133
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Arhgdia	IDA		Mouse	PMID:18829665
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Arhgdia	IMP		Mouse	PMID:18829665
Biological Process	GO:0007266	Rho protein signal transduction	Arhgdia	IDA		Mouse	PMID:15093731
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Arhgdia	IMP		Mouse	MGI:MGI:5532914|PMID:20696765
Biological Process	GO:0007264	small GTPase mediated signal transduction	arhgdia	IMP	ZFIN:ZDB-MRPHLNO-130826-1	Zfish	PMID:23867502

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern