Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGEF11
  • Mouse genes Arhgef11
  • Rat genes Arhgef11
  • Zfish genes arhgef11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	ARHGEF11	IDA		Human	PMID:15755723
Molecular Function	GO:0001965	G-protein alpha-subunit binding	arhgef11	IPI	UniProtKB:Q5YKG3	Zfish	PMID:19307601
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:Q03113	Human	PMID:10026210
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:Q14344	Human	PMID:10026210
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:P61586	Human	PMID:15530360
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:P46108	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:P61586	Human	PMID:20300064
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:Q7DB74	Human	PMID:20300064
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:Q8N6F7	Human	PMID:20844236
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:P61586	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	ARHGEF11	IPI	UniProtKB:P61586	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Arhgef11	IPI	UniProtKB:B2RXS4|UniProtKB:Q8CJH3	Mouse	MGI:MGI:5508282|PMID:12123608
Molecular Function	GO:0005515	protein binding	Arhgef11	IPI	RGD:620340	Rat	PMID:11242047|RGD:631920
Molecular Function	GO:0005515	protein binding	Arhgef11	IPI	RGD:619921	Rat	PMID:17620967|RGD:1642801
Molecular Function	GO:0005515	protein binding	Arhgef11	IPI	UniProtKB:P27601	Rat	PMID:18940608|RGD:13432349
Cellular Component	GO:0005737	cytoplasm	ARHGEF11	IDA		Human	PMID:15755723
Cellular Component	GO:0005654	nucleoplasm	ARHGEF11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ARHGEF11	IDA		Human	GO_REF:0000052
Biological Process	GO:0007368	determination of left/right symmetry	arhgef11	IMP	ZFIN:ZDB-GENO-070306-1	Zfish	PMID:17267448
Biological Process	GO:0007368	determination of left/right symmetry	arhgef11	IMP	ZFIN:ZDB-MRPHLNO-070606-3	Zfish	PMID:17267448
Biological Process	GO:0007368	determination of left/right symmetry	arhgef11	IMP	ZFIN:ZDB-MRPHLNO-070606-4	Zfish	PMID:17267448
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	arhgef11	IMP	ZFIN:ZDB-MRPHLNO-070606-3	Zfish	PMID:17267448
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ARHGEF11	IDA		Human	PMID:15755723
Biological Process	GO:0048840	otolith development	arhgef11	IMP	ZFIN:ZDB-MRPHLNO-070606-4	Zfish	PMID:17267448
Biological Process	GO:0048840	otolith development	arhgef11	IMP	ZFIN:ZDB-GENO-070306-1	Zfish	PMID:17267448
Biological Process	GO:0048840	otolith development	arhgef11	IMP	ZFIN:ZDB-MRPHLNO-070606-3	Zfish	PMID:17267448
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ARHGEF11	IDA		Human	PMID:10026210
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	arhgef11	IMP		Zfish	PMID:19307601
Biological Process	GO:0007266	Rho protein signal transduction	ARHGEF11	IDA		Human	PMID:10026210
Biological Process	GO:0043149	stress fiber assembly	arhgef11	IDA		Zfish	PMID:17267448

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern