Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGEF15
  • Mouse genes Arhgef15
  • Rat genes Arhgef15
  • Zfish genes arhgef15a,arhgef15b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF15	IDA		Human	PMID:12775584
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Arhgef15	IDA		Mouse	MGI:MGI:4881358|PMID:21029865
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Arhgef15	IDA		Rat	PMID:12775584|RGD:8554375
Molecular Function	GO:0005515	protein binding	ARHGEF15	IPI	UniProtKB:P54764	Human	PMID:12775584
Molecular Function	GO:0005515	protein binding	ARHGEF15	IPI	UniProtKB:Q53EZ4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ARHGEF15	IPI	UniProtKB:Q13976-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARHGEF15	IPI	UniProtKB:Q53EZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARHGEF15	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Arhgef15	IPI	UniProtKB:P54763	Mouse	MGI:MGI:4881358|PMID:21029865
Molecular Function	GO:0005515	protein binding	Arhgef15	IPI	UniProtKB:D3ZZK3	Rat	PMID:12775584|RGD:8554375
Cellular Component	GO:0005737	cytoplasm	Arhgef15	IDA		Rat	PMID:12775584|RGD:8554375
Cellular Component	GO:0030425	dendrite	Arhgef15	IDA		Mouse	MGI:MGI:4881358|PMID:21029865
Cellular Component	GO:0098978	glutamatergic synapse	Arhgef15	IDA		Mouse	PMID:28185854
Cellular Component	GO:0098978	glutamatergic synapse	Arhgef15	IMP		Mouse	PMID:28185854
Cellular Component	GO:0098794	postsynapse	Arhgef15	IDA		Mouse	PMID:28185854
Cellular Component	GO:0098794	postsynapse	Arhgef15	IMP		Mouse	PMID:28185854
Biological Process	GO:2000297	negative regulation of synapse maturation	Arhgef15	IMP		Mouse	MGI:MGI:4881358|PMID:21029865
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Arhgef15	IDA		Rat	PMID:12775584|RGD:8554375
Biological Process	GO:0050790	regulation of catalytic activity	ARHGEF15	IDA		Human	PMID:12775584
Biological Process	GO:0050790	regulation of catalytic activity	Arhgef15	IDA		Rat	PMID:12775584|RGD:8554375
Biological Process	GO:0150052	regulation of postsynapse assembly	Arhgef15	IMP		Mouse	PMID:28185854
Biological Process	GO:0150052	regulation of postsynapse assembly	Arhgef15	IDA		Mouse	PMID:28185854
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	Arhgef15	IMP	MGI:MGI:3812708	Mouse	PMID:22535667

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern