Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Arhgef7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ARHGEF7
- Mouse genes Arhgef7
- Rat genes Arhgef7
- Zfish genes arhgef7a,arhgef7b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgef7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	ARHGEF7	IDA		Human	PMID:27012601
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF7	EXP		Human	PMID:12695502
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF7	EXP		Human	PMID:17310244
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ARHGEF7	IDA		Human	PMID:21048939
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Arhgef7	IDA		Mouse	PMID:21828338
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P49593	Human	PMID:11864573
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:11864573
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q8WY54	Human	PMID:11864573
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14160	Human	PMID:15182672
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:16101281
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13177	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P22681	Human	PMID:16407834
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:16407834
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P63000	Human	PMID:16492808
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:16492808
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:16628223
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q9Y2X7	Human	PMID:16628223
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13177	Human	PMID:16787945
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q9Y2X7	Human	PMID:16787945
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:O60880-1	Human	PMID:16983070
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P60953-2	Human	PMID:16983070
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14160	Human	PMID:19041750
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14CM0	Human	PMID:19118189
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14160	Human	PMID:19555689
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:O14745	Human	PMID:20395446
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q5S007	Human	PMID:21048939
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14160	Human	PMID:21132015
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P41227	Human	PMID:21295525
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q9Y2X7	Human	PMID:21295525
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q9BYB0	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P63000	Human	PMID:24792722
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P30153	Human	PMID:25150978
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P60953-2	Human	PMID:25150978
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q7Z6B7	Human	PMID:25150978
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q5S007	Human	PMID:25500533
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q14160	Human	PMID:26617989
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q9Y2X7	Human	PMID:27012601
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q9UPX8	Human	PMID:32661924
Molecular Function	GO:0005515	protein binding	ARHGEF7	IPI	UniProtKB:Q13153	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q68FF6	Mouse	MGI:MGI:3815295\|PMID:16959763
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q9JLU4\|UniProtKB:Q9QX74\|UniProtKB:Q9WV48	Mouse	MGI:MGI:2662659\|PMID:12626503
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q9JLQ2	Mouse	MGI:MGI:3688344\|PMID:15102471
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q9HBI1	Mouse	MGI:MGI:5447607\|PMID:18325335
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q68FF6	Mouse	MGI:MGI:5284757\|PMID:19022416
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q9ES46	Mouse	MGI:MGI:5527016\|PMID:24035453
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q14161\|UniProtKB:Q9Z272	Mouse	MGI:MGI:5294524\|PMID:21295525
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	PR:Q68FF6	Mouse	PMID:10428811
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	PR:P60766	Mouse	PMID:21828338
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q9Z272	Rat	PMID:12473661\|RGD:9850090
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	RGD:620624	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	RGD:69331	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q13191-1	Rat	PMID:16228008\|RGD:13432248
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q13177	Rat	PMID:16527308\|RGD:8554558
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	RGD:1565055	Rat	PMID:17081755\|RGD:2303059
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:P41227	Rat	PMID:21295525\|RGD:8553358
Molecular Function	GO:0005515	protein binding	Arhgef7	IPI	UniProtKB:Q9Z272	Rat	PMID:24297929\|RGD:42721994
Molecular Function	GO:0019901	protein kinase binding	ARHGEF7	IPI	UniProtKB:Q5S007	Human	PMID:21048939
Molecular Function	GO:0019901	protein kinase binding	Arhgef7	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:5318010\|PMID:21048939
Molecular Function	GO:0019901	protein kinase binding	Arhgef7	IPI	RGD:732793	Rat	PMID:16527308\|RGD:8554558
Molecular Function	GO:0031267	small GTPase binding	Arhgef7	IPI	UniProtKB:Q13153,UniProtKB:Q9DE64	Rat	PMID:11950598\|RGD:8554487
Cellular Component	GO:0005813	centrosome	ARHGEF7	IDA		Human	PMID:27012601
Cellular Component	GO:0005737	cytoplasm	Arhgef7	IDA		Rat	PMID:17081755\|RGD:2303059
Cellular Component	GO:0005829	cytosol	Arhgef7	IDA		Mouse	PMID:21828338
Cellular Component	GO:0005925	focal adhesion	ARHGEF7	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Arhgef7	IDA		Rat	PMID:17081755\|RGD:2303059
Cellular Component	GO:0098982	GABA-ergic synapse	Arhgef7	IDA		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0098982	GABA-ergic synapse	Arhgef7	IMP		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0030426	growth cone	Arhgef7	IDA		Rat	PMID:12226077\|RGD:633693
Cellular Component	GO:0030027	lamellipodium	Arhgef7	IDA		Mouse	MGI:MGI:5447607\|PMID:18325335
Cellular Component	GO:0016020	membrane	Arhgef7	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0097431	mitotic spindle pole	ARHGEF7	IDA		Human	PMID:27012601
Cellular Component	GO:0043005	neuron projection	ARHGEF7	IDA		Human	PMID:21048939
Cellular Component	GO:0043025	neuronal cell body	ARHGEF7	IDA		Human	PMID:21048939
Cellular Component	GO:0005886	plasma membrane	Arhgef7	IDA		Mouse	PMID:21828338
Cellular Component	GO:0098794	postsynapse	Arhgef7	IDA		Mouse	MGI:MGI:5545681\|PMID:24297929
Cellular Component	GO:0014069	postsynaptic density	Arhgef7	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0032991	protein-containing complex	ARHGEF7	IDA		Human	PMID:11864573
Cellular Component	GO:0032991	protein-containing complex	Arhgef7	IDA		Rat	PMID:11950598\|RGD:8554487
Cellular Component	GO:0000322	storage vacuole	Arhgef7	IDA		Mouse	PMID:21828338
Cellular Component	GO:0045202	synapse	Arhgef7	IDA		Rat	PMID:12629171\|RGD:152995492
Biological Process	GO:0001525	angiogenesis	arhgef7b	IMP	ZFIN:ZDB-GENO-120907-1	Zfish	PMID:22206757
Biological Process	GO:0043615	astrocyte cell migration	Arhgef7	IMP		Rat	PMID:17081755\|RGD:2303059
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-MRPHLNO-071213-3	Zfish	PMID:17573532
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-GENO-071213-1	Zfish	PMID:17573532
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-MRPHLNO-071214-2	Zfish	PMID:17573532
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-MRPHLNO-071213-2	Zfish	PMID:17573532
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-GENO-071212-3	Zfish	PMID:17573532
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-GENO-120907-1	Zfish	PMID:22206757
Biological Process	GO:0001568	blood vessel development	arhgef7b	IMP	ZFIN:ZDB-MRPHLNO-071213-1	Zfish	PMID:17573532
Biological Process	GO:0001935	endothelial cell proliferation	arhgef7b	IMP	ZFIN:ZDB-GENO-120907-1	Zfish	PMID:22206757
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	arhgef7b	IMP	ZFIN:ZDB-MRPHLNO-100617-8	Zfish	PMID:20405038
Biological Process	GO:0048041	focal adhesion assembly	ARHGEF7	HDA		Human	PMID:21423176
Biological Process	GO:0007030	Golgi organization	ARHGEF7	IMP		Human	PMID:25500533
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Arhgef7	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0030032	lamellipodium assembly	Arhgef7	IMP		Mouse	MGI:MGI:5447607\|PMID:18325335
Biological Process	GO:1905833	negative regulation of microtubule nucleation	ARHGEF7	IMP		Human	PMID:27012601
Biological Process	GO:0043065	positive regulation of apoptotic process	ARHGEF7	IMP		Human	PMID:19041750
Biological Process	GO:0010763	positive regulation of fibroblast migration	ARHGEF7	HDA		Human	PMID:21423176
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Arhgef7	IMP		Mouse	PMID:21828338
Biological Process	GO:0043547	positive regulation of GTPase activity	ARHGEF7	IDA		Human	PMID:21048939
Biological Process	GO:0043547	positive regulation of GTPase activity	ARHGEF7	HMP		Human	PMID:21423176
Biological Process	GO:0043547	positive regulation of GTPase activity	Arhgef7	HMP		Mouse	MGI:MGI:5582159\|PMID:21423176
Biological Process	GO:0043547	positive regulation of GTPase activity	Arhgef7	IMP		Mouse	PMID:21828338
Biological Process	GO:2000394	positive regulation of lamellipodium morphogenesis	ARHGEF7	HMP		Human	PMID:21423176
Biological Process	GO:0032092	positive regulation of protein binding	Arhgef7	IMP		Mouse	PMID:21828338
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ARHGEF7	HMP		Human	PMID:21423176
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Arhgef7	IDA		Rat	PMID:25284783\|RGD:13702191
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Arhgef7	IMP		Rat	PMID:25284783\|RGD:13702191
Biological Process	GO:0099140	presynaptic actin cytoskeleton organization	Arhgef7	IDA		Rat	PMID:22114281\|RGD:13702413
Biological Process	GO:0099140	presynaptic actin cytoskeleton organization	Arhgef7	IMP		Rat	PMID:22114281\|RGD:13702413
Biological Process	GO:0071896	protein localization to adherens junction	arhgef7b	IMP	ZFIN:ZDB-MRPHLNO-100617-8	Zfish	PMID:20405038
Biological Process	GO:1904424	regulation of GTP binding	ARHGEF7	IMP		Human	PMID:25500533
Biological Process	GO:0007264	small GTPase mediated signal transduction	Arhgef7	IDA		Rat	PMID:12226077\|RGD:633693

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.