Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARL3
  • Mouse genes Arl3
  • Rat genes Arl3
  • Zfish genes arl3a,arl3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	ARL3	IDA		Human	PMID:18588884
Molecular Function	GO:0019003	GDP binding	Arl3	IDA		Mouse	MGI:MGI:3584319|PMID:15979089
Molecular Function	GO:0019003	GDP binding	Arl3	IDA		Rat	PMID:8034651|RGD:68742
Molecular Function	GO:0005525	GTP binding	ARL3	IDA		Human	PMID:18588884
Molecular Function	GO:0005525	GTP binding	ARL3	IDA		Human	PMID:22085962
Molecular Function	GO:0005525	GTP binding	Arl3	IDA		Mouse	MGI:MGI:3584319|PMID:15979089
Molecular Function	GO:0005525	GTP binding	Arl3	IDA		Mouse	MGI:MGI:4943386|PMID:18376416
Molecular Function	GO:0005525	GTP binding	Arl3	IDA		Mouse	PMID:10518933
Molecular Function	GO:0005525	GTP binding	Arl3	IDA		Rat	PMID:8034651|RGD:68742
Molecular Function	GO:0003924	GTPase activity	Arl3	IDA		Mouse	MGI:MGI:1928255|PMID:10518933
Molecular Function	GO:0003924	GTPase activity	Arl3	IDA		Mouse	MGI:MGI:4943386|PMID:18376416
Molecular Function	GO:0000287	magnesium ion binding	Arl3	IDA		Mouse	MGI:MGI:5925653|PMID:26455799
Molecular Function	GO:0008017	microtubule binding	ARL3	IDA		Human	PMID:12417528
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O75695	Human	PMID:11847227
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q9Y2Y0	Human	PMID:11847227
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O43924	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O43924	Human	PMID:18588884
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:18588884
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:A6NIH7	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q5TEA3	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O43924	Human	PMID:26455799
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:26455799
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q9Y2Y0	Human	PMID:26455799
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q9Y2Y0	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O43924	Human	PMID:30257685
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O43924	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:O60907	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q13432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARL3	IPI	UniProtKB:Q9Y2Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:Q13432	Mouse	MGI:MGI:5508704|PMID:22960633
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:Q8C6E0|UniProtKB:Q96G28	Mouse	MGI:MGI:5925653|PMID:26455799
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:O75695	Mouse	MGI:MGI:4943386|PMID:18376416
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:O43924	Mouse	MGI:MGI:5508674|PMID:23559067
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:O75695	Mouse	MGI:MGI:5925653|PMID:26455799
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:O75695	Mouse	MGI:MGI:5926736|PMID:16472755
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:Q8R0H9	Mouse	MGI:MGI:6210198|PMID:25405894
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:O55057	Mouse	MGI:MGI:1928255|PMID:10518933
Molecular Function	GO:0005515	protein binding	Arl3	IPI	UniProtKB:O55057	Mouse	MGI:MGI:3584319|PMID:15979089
Cellular Component	GO:0005930	axoneme	Arl3	IDA		Mouse	MGI:MGI:5925653|PMID:26455799
Cellular Component	GO:0005813	centrosome	ARL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	ARL3	IDA		Human	PMID:16525022
Cellular Component	GO:0036064	ciliary basal body	Arl3	IDA		Mouse	MGI:MGI:5925653|PMID:26455799
Cellular Component	GO:0035869	ciliary transition zone	Arl3	IDA		Mouse	MGI:MGI:5925653|PMID:26455799
Cellular Component	GO:0005929	cilium	ARL3	IDA		Human	PMID:16525022
Cellular Component	GO:0005881	cytoplasmic microtubule	ARL3	IDA		Human	PMID:12417528
Cellular Component	GO:0070062	extracellular exosome	ARL3	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	ARL3	IDA		Human	PMID:16525022
Cellular Component	GO:0030496	midbody	ARL3	IDA		Human	PMID:16525022
Cellular Component	GO:0005654	nucleoplasm	ARL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ARL3	IDA		Human	PMID:16525022
Cellular Component	GO:0032391	photoreceptor connecting cilium	ARL3	IDA		Human	PMID:12417528
Cellular Component	GO:0005876	spindle microtubule	ARL3	IDA		Human	PMID:16525022
Biological Process	GO:0060271	cilium assembly	ARL3	IMP		Human	PMID:22085962
Biological Process	GO:0060271	cilium assembly	arl3b	IMP		Zfish	PMID:22085962|ZFIN:ZDB-PUB-120416-1
Biological Process	GO:0006893	Golgi to plasma membrane transport	Arl3	IMP		Mouse	MGI:MGI:6210198|PMID:25405894
Biological Process	GO:0042073	intraciliary transport	Arl3	IMP		Mouse	PMID:21289087
Biological Process	GO:0001822	kidney development	Arl3	IMP		Mouse	MGI:MGI:3620864|PMID:16565502
Biological Process	GO:0000281	mitotic cytokinesis	ARL3	IMP		Human	PMID:16525022
Biological Process	GO:0042461	photoreceptor cell development	Arl3	IMP		Mouse	MGI:MGI:3620864|PMID:16565502
Biological Process	GO:0006892	post-Golgi vesicle-mediated transport	ARL3	IMP		Human	PMID:20106869
Biological Process	GO:1903441	protein localization to ciliary membrane	Arl3	IMP		Mouse	MGI:MGI:6210198|PMID:25405894
Biological Process	GO:0061512	protein localization to cilium	ARL3	IMP		Human	PMID:30269812
Biological Process	GO:0007264	small GTPase mediated signal transduction	ARL3	IDA		Human	PMID:22085962
Biological Process	GO:0007224	smoothened signaling pathway	Arl3	IMP		Mouse	PMID:21289087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern