Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARL6
  • Mouse genes Arl6
  • Rat genes Arl6
  • Zfish genes arl6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arl6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARL6	IPI	UniProtKB:Q8NFJ9	Human	PMID:20603001
Molecular Function	GO:0005515	protein binding	ARL6	IPI	UniProtKB:Q8NFJ9	Human	PMID:22139371
Molecular Function	GO:0005515	protein binding	ARL6	IPI	UniProtKB:Q9BW83	Human	PMID:25443296
Molecular Function	GO:0005515	protein binding	Arl6	IPI	PR:Q8BH07	Mouse	PMID:10508919
Molecular Function	GO:0005515	protein binding	Arl6	IPI	PR:Q9JM93	Mouse	PMID:10508919
Molecular Function	GO:0005515	protein binding	Arl6	IPI	PR:Q8R5J9	Mouse	PMID:10508919
Molecular Function	GO:0005515	protein binding	Arl6	IPI	PR:Q6PA06	Mouse	PMID:10508919
Molecular Function	GO:0005515	protein binding	Arl6	IPI	PR:Q9JKW0	Mouse	PMID:10508919
Cellular Component	GO:0005929	cilium	ARL6	IDA		Human	PMID:22139371
Cellular Component	GO:0005737	cytoplasm	Arl6	IDA		Mouse	PMID:10508919
Cellular Component	GO:0005829	cytosol	Arl6	IDA		Mouse	PMID:22139371
Cellular Component	GO:0070062	extracellular exosome	ARL6	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	Arl6	IDA		Mouse	PMID:10508919
Cellular Component	GO:0016020	membrane	Arl6	IDA		Mouse	PMID:22139371
Cellular Component	GO:0015630	microtubule cytoskeleton	ARL6	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	Arl6	IMP	MGI:MGI:5310744	Mouse	PMID:22139371
Biological Process	GO:0060271	cilium assembly	ARL6	IMP		Human	PMID:20207729
Biological Process	GO:0060271	cilium assembly	Arl6	IMP	MGI:MGI:5310744	Mouse	PMID:22139371
Biological Process	GO:0060271	cilium assembly	arl6	IMP		Zfish	PMID:18381349|ZFIN:ZDB-PUB-080408-14
Biological Process	GO:0007368	determination of left/right symmetry	arl6	IMP		Zfish	PMID:18381349|ZFIN:ZDB-PUB-080408-14
Biological Process	GO:0007368	determination of left/right symmetry	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-4	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	arl6	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	arl6	IGI	ZFIN:ZDB-MRPHLNO-081027-1,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0045444	fat cell differentiation	Arl6	IEP		Mouse	MGI:MGI:3794016|PMID:17379567
Biological Process	GO:0007369	gastrulation	arl6	IMP	ZFIN:ZDB-MRPHLNO-131205-2	Zfish	PMID:20498079
Biological Process	GO:0070121	Kupffer's vesicle development	arl6	IGI	ZFIN:ZDB-MRPHLNO-081027-1,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:20333246
Biological Process	GO:0070121	Kupffer's vesicle development	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-4	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	arl6	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	arl6	IMP		Zfish	PMID:18381349|ZFIN:ZDB-PUB-080408-14
Biological Process	GO:0032402	melanosome transport	arl6	IGI	ZFIN:ZDB-MRPHLNO-081027-1,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-4	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:20333246
Biological Process	GO:0032402	melanosome transport	arl6	IMP	ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	arl6	IMP		Zfish	PMID:21282186
Biological Process	GO:0032402	melanosome transport	arl6	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0033339	pectoral fin development	arl6	IGI	ZFIN:ZDB-MRPHLNO-081027-1,ZFIN:ZDB-MRPHLNO-081027-3	Zfish	PMID:18381349
Biological Process	GO:0061512	protein localization to cilium	ARL6	IMP		Human	PMID:22139371
Biological Process	GO:0097499	protein localization to non-motile cilium	Arl6	IDA		Mouse	MGI:MGI:5603942|PMID:24939912
Biological Process	GO:1903445	protein transport from ciliary membrane to plasma membrane	Arl6	IMP	MGI:MGI:5310744	Mouse	PMID:22139371
Biological Process	GO:0008593	regulation of Notch signaling pathway	arl6	IMP	ZFIN:ZDB-MRPHLNO-131205-2	Zfish	PMID:24681783
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Arl6	IMP	MGI:MGI:5310744	Mouse	PMID:22139371
Biological Process	GO:0010842	retina layer formation	Arl6	IMP	MGI:MGI:5310744	Mouse	PMID:22139371
Biological Process	GO:0010842	retina layer formation	Arl6	IMP	MGI:MGI:4442928	Mouse	PMID:20333246
Biological Process	GO:0007601	visual perception	arl6	IMP	ZFIN:ZDB-MRPHLNO-100504-6	Zfish	PMID:20333246
Biological Process	GO:0016055	Wnt signaling pathway	ARL6	IMP		Human	PMID:20207729

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern