Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARL6IP5
  • Mouse genes Arl6ip5
  • Rat genes Arl6ip5
  • Zfish genes arl6ip5a,arl6ip5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arl6ip5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARL6IP5	IPI	UniProtKB:Q96GF1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARL6IP5	IPI	UniProtKB:Q9NQG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Arl6ip5	IPI	UniProtKB:P51906|UniProtKB:Q9JKW0	Mouse	MGI:MGI:3822963|PMID:18684713
Molecular Function	GO:0005515	protein binding	Arl6ip5	IPI	UniProtKB:P51906	Mouse	PMID:18799673
Molecular Function	GO:0005515	protein binding	Arl6ip5	IPI	PR:O88848	Mouse	PMID:10508919
Molecular Function	GO:0005515	protein binding	Arl6ip5	IPI	UniProtKB:Q6WN19	Rat	PMID:18096700|RGD:40902968
Molecular Function	GO:0044325	transmembrane transporter binding	Arl6ip5	IDA		Rat	PMID:11242046|RGD:1299537
Cellular Component	GO:0005737	cytoplasm	Arl6ip5	IDA		Rat	PMID:11242046|RGD:1299537
Cellular Component	GO:0016020	membrane	ARL6IP5	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Arl6ip5	IDA		Rat	PMID:11242046|RGD:1299537
Cellular Component	GO:0005886	plasma membrane	Arl6ip5	IPI	UniProtKB:P51906	Mouse	PMID:18799673
Cellular Component	GO:0099523	presynaptic cytosol	Arl6ip5	IDA		Mouse	PMID:17897781
Biological Process	GO:0071407	cellular response to organic cyclic compound	ARL6IP5	IDA		Human	PMID:12562531
Biological Process	GO:0071407	cellular response to organic cyclic compound	Arl6ip5	IDA		Mouse	PMID:12562531
Biological Process	GO:0034599	cellular response to oxidative stress	Arl6ip5	IMP	MGI:MGI:5315599	Mouse	PMID:22210510
Biological Process	GO:0006749	glutathione metabolic process	Arl6ip5	IMP	MGI:MGI:5315599	Mouse	PMID:22210510
Biological Process	GO:0006749	glutathione metabolic process	Arl6ip5	IMP		Mouse	PMID:18799673
Biological Process	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	ARL6IP5	IDA		Human	PMID:18387645
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Arl6ip5	IDA		Mouse	PMID:12119102
Biological Process	GO:0015813	L-glutamate transmembrane transport	Arl6ip5	IDA		Mouse	PMID:12119102
Biological Process	GO:0007611	learning or memory	Arl6ip5	IMP	MGI:MGI:5315599	Mouse	PMID:22210510
Biological Process	GO:0002037	negative regulation of L-glutamate import across plasma membrane	Arl6ip5	IDA		Mouse	MGI:MGI:3822963|PMID:18684713
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	ARL6IP5	IMP		Human	PMID:18387645
Biological Process	GO:0051051	negative regulation of transport	Arl6ip5	IMP		Rat	PMID:11242046|RGD:1299537
Biological Process	GO:0043065	positive regulation of apoptotic process	ARL6IP5	IMP		Human	PMID:18387645
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ARL6IP5	IMP		Human	PMID:18387645
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	ARL6IP5	IMP		Human	PMID:18387645
Biological Process	GO:0072659	protein localization to plasma membrane	Arl6ip5	IMP	MGI:MGI:5315599	Mouse	PMID:22210510
Biological Process	GO:0015031	protein transport	ARL6IP5	IDA		Human	PMID:18167356
Biological Process	GO:0051580	regulation of neurotransmitter uptake	Arl6ip5	IDA		Rat	PMID:11242046|RGD:1299537
Biological Process	GO:0051580	regulation of neurotransmitter uptake	Arl6ip5	IMP		Rat	PMID:11242046|RGD:1299537

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern