Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARL8B
  • Mouse genes Arl8b
  • Rat genes Arl8b
  • Zfish genes arl8ba,arl8bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arl8b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	ARL8B	IDA		Human	PMID:15331635
Molecular Function	GO:0048487	beta-tubulin binding	ARL8B	IDA		Human	PMID:15331635
Molecular Function	GO:0003925	G protein activity	ARL8B	IDA		Human	PMID:16537643
Molecular Function	GO:0019003	GDP binding	ARL8B	IDA		Human	PMID:15331635
Molecular Function	GO:0019003	GDP binding	ARL8B	IMP		Human	PMID:16650381
Molecular Function	GO:0005525	GTP binding	ARL8B	IDA		Human	PMID:15331635
Molecular Function	GO:0005525	GTP binding	ARL8B	IMP		Human	PMID:16650381
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:P49754	Human	PMID:21802320
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q8IWE5	Human	PMID:22172677
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q969J3	Human	PMID:25898167
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q13573	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q8IWE5|UniProtKB:Q9Y4G2	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q9Y4G2	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARL8B	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Cellular Component	GO:0030424	axon	Arl8b	IDA		Mouse	MGI:MGI:6269290|PMID:30174114
Cellular Component	GO:0101004	cytolytic granule membrane	ARL8B	IDA		Human	PMID:24088571
Cellular Component	GO:0005737	cytoplasm	ARL8B	IDA		Human	PMID:15331635
Cellular Component	GO:0070062	extracellular exosome	ARL8B	HDA		Human	PMID:19056867
Cellular Component	GO:0005765	lysosomal membrane	ARL8B	IDA		Human	PMID:25898167
Cellular Component	GO:0005765	lysosomal membrane	ARL8B	IDA		Human	PMID:27808481
Cellular Component	GO:0005765	lysosomal membrane	ARL8B	IDA		Human	PMID:22172677
Cellular Component	GO:0005764	lysosome	ARL8B	IMP		Human	PMID:16650381
Cellular Component	GO:0005764	lysosome	ARL8B	IDA		Human	PMID:21802320
Cellular Component	GO:0005764	lysosome	ARL8B	IDA		Human	PMID:28325809
Cellular Component	GO:0005764	lysosome	ARL8B	IDA		Human	PMID:29592961
Cellular Component	GO:0005764	lysosome	Arl8b	IDA		Mouse	MGI:MGI:6508507|PMID:25637027
Cellular Component	GO:0016020	membrane	ARL8B	HDA		Human	PMID:19946888
Cellular Component	GO:0030496	midbody	ARL8B	IDA		Human	PMID:15331635
Cellular Component	GO:0051233	spindle midzone	ARL8B	IDA		Human	PMID:15331635
Cellular Component	GO:0045202	synapse	Arl8b	IDA		Mouse	MGI:MGI:6269290|PMID:30174114
Biological Process	GO:0008089	anterograde axonal transport	Arl8b	IDA		Mouse	MGI:MGI:6269290|PMID:30174114
Biological Process	GO:0002747	antigen processing and presentation following phagocytosis	ARL8B	IMP		Human	PMID:21802320
Biological Process	GO:0002505	antigen processing and presentation of polysaccharide antigen via MHC class II	Arl8b	IDA		Mouse	MGI:MGI:6508507|PMID:25637027
Biological Process	GO:0061909	autophagosome-lysosome fusion	ARL8B	IMP		Human	PMID:28325809
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	ARL8B	IMP		Human	PMID:29592961
Biological Process	GO:0007059	chromosome segregation	ARL8B	IMP		Human	PMID:14871887
Biological Process	GO:0016197	endosomal transport	Arl8b	IMP		Mouse	PMID:24841562
Biological Process	GO:0090117	endosome to lysosome transport of low-density lipoprotein particle	ARL8B	IMP		Human	PMID:21802320
Biological Process	GO:1902774	late endosome to lysosome transport	ARL8B	IMP		Human	PMID:28325809
Biological Process	GO:1902774	late endosome to lysosome transport	Arl8b	IDA		Mouse	MGI:MGI:6508507|PMID:25637027
Biological Process	GO:0032418	lysosome localization	ARL8B	IDA		Human	PMID:16537643
Biological Process	GO:0032418	lysosome localization	ARL8B	IMP		Human	PMID:16650381
Biological Process	GO:0032418	lysosome localization	ARL8B	IMP		Human	PMID:21802320
Biological Process	GO:0032418	lysosome localization	ARL8B	IMP		Human	PMID:22172677
Biological Process	GO:0032418	lysosome localization	ARL8B	IMP		Human	PMID:25898167
Biological Process	GO:0032418	lysosome localization	ARL8B	IDA		Human	PMID:27808481
Biological Process	GO:0032418	lysosome localization	ARL8B	IDA		Human	PMID:28325809
Biological Process	GO:0032418	lysosome localization	ARL8B	IMP		Human	PMID:29592961
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	ARL8B	IMP		Human	PMID:24088571
Biological Process	GO:0090385	phagosome-lysosome fusion	ARL8B	IMP		Human	PMID:21802320
Biological Process	GO:0001778	plasma membrane repair	ARL8B	IMP		Human	PMID:29592961
Biological Process	GO:0046754	viral exocytosis	ARL8B	IMP		Human	PMID:33157038
Biological Process	GO:0046754	viral exocytosis	Arl8b	IMP		Mouse	MGI:MGI:6508519|PMID:33157038

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern