Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARNT2
  • Mouse genes Arnt2
  • Rat genes Arnt2
  • Zfish genes arnt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arnt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017162	aryl hydrocarbon receptor binding	Arnt2	IPI	UniProtKB:P30561	Mouse	MGI:MGI:79449|PMID:8657146
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Arnt2	IDA		Mouse	MGI:MGI:79449|PMID:8657146
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Arnt2	IDA		Mouse	MGI:MGI:79449|PMID:8657146
Molecular Function	GO:0003700	DNA-binding transcription factor activity	arnt2	IDA		Zfish	PMID:11072074|ZFIN:ZDB-PUB-001205-13
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ARNT2	IDA		Human	PMID:24465693
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q8IUM7	Human	PMID:24465693
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q86UW9	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:P25791-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:P81133	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q6NZ36-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q9BXS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q9UJX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q9Y2T2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARNT2	IPI	UniProtKB:Q9Y6W3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Arnt2	IPI	PR:Q8BGD7	Mouse	PMID:27782878
Molecular Function	GO:0005515	protein binding	Arnt2	IPI	PR:Q61045	Mouse	PMID:27782878
Molecular Function	GO:0046982	protein heterodimerization activity	ARNT2	IPI	UniProtKB:Q16665	Human	PMID:12239177
Molecular Function	GO:0046982	protein heterodimerization activity	ARNT2	IDA		Human	PMID:24465693
Molecular Function	GO:0046982	protein heterodimerization activity	Arnt2	IPI	UniProtKB:Q61045|UniProtKB:Q61079	Mouse	MGI:MGI:82794|PMID:8927054
Molecular Function	GO:0046982	protein heterodimerization activity	Arnt2	IDA		Mouse	MGI:MGI:5824181|PMID:27782878
Molecular Function	GO:0044877	protein-containing complex binding	Arnt2	IDA		Rat	PMID:11029639|RGD:2301215
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Arnt2	IDA		Mouse	MGI:MGI:79449|PMID:8657146
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Arnt2	IDA		Mouse	PMID:14701734
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ARNT2	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	ARNT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ARNT2	IDA		Human	PMID:12239177
Cellular Component	GO:0005634	nucleus	ARNT2	IDA		Human	PMID:24465693
Cellular Component	GO:0005634	nucleus	Arnt2	IDA		Rat	PMID:10873592|RGD:2301216
Cellular Component	GO:0005667	transcription regulator complex	Arnt2	IDA		Mouse	PMID:14701734
Biological Process	GO:0007411	axon guidance	arnt2	IGI	ZFIN:ZDB-MRPHLNO-100423-10,ZFIN:ZDB-MRPHLNO-100423-8	Zfish	PMID:23222439
Biological Process	GO:0007411	axon guidance	arnt2	IMP	ZFIN:ZDB-MRPHLNO-100423-8	Zfish	PMID:23222439
Biological Process	GO:0007420	brain development	ARNT2	IMP		Human	PMID:24022475
Biological Process	GO:0003208	cardiac ventricle morphogenesis	arnt2	IMP	ZFIN:ZDB-GENO-100415-7	Zfish	PMID:19374551
Biological Process	GO:0098609	cell-cell adhesion	arnt2	IMP	ZFIN:ZDB-MRPHLNO-100414-6	Zfish	PMID:19123687
Biological Process	GO:0007417	central nervous system development	Arnt2	IMP		Mouse	MGI:MGI:2157648|PMID:11318878
Biological Process	GO:0021536	diencephalon development	arnt2	IMP	ZFIN:ZDB-GENO-100423-2	Zfish	PMID:19234064
Biological Process	GO:0071542	dopaminergic neuron differentiation	arnt2	IMP	ZFIN:ZDB-GENO-100423-2	Zfish	PMID:19234064
Biological Process	GO:0021979	hypothalamus cell differentiation	arnt2	IMP	ZFIN:ZDB-GENO-100423-2	Zfish	PMID:19234064
Biological Process	GO:0001701	in utero embryonic development	Arnt2	IEP		Mouse	MGI:MGI:2448795|PMID:12502753
Biological Process	GO:0072576	liver morphogenesis	arnt2	IMP	ZFIN:ZDB-GENO-100415-7	Zfish	PMID:19374551
Biological Process	GO:0043066	negative regulation of apoptotic process	Arnt2	IMP		Rat	PMID:11029639|RGD:2301215
Biological Process	GO:0008284	positive regulation of cell population proliferation	Arnt2	IMP		Rat	PMID:11029639|RGD:2301215
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Arnt2	IDA		Mouse	MGI:MGI:79449|PMID:8657146
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	arnt2	IPI	UniProtKB:Q9DG12,UniProtKB:Q9YGV3	Zfish	PMID:16306231
Biological Process	GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	arnt2	IMP	ZFIN:ZDB-GENO-210727-1,ZFIN:ZDB-CRISPR-201102-5,ZFIN:ZDB-CRISPR-201102-6,ZFIN:ZDB-CRISPR-201102-7,ZFIN:ZDB-CRISPR-201102-8	Zfish	PMID:32379754
Biological Process	GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	arnt2	IMP	ZFIN:ZDB-GENO-180302-1,ZFIN:ZDB-CRISPR-201102-5,ZFIN:ZDB-CRISPR-201102-6,ZFIN:ZDB-CRISPR-201102-7,ZFIN:ZDB-CRISPR-201102-8	Zfish	PMID:32379754
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ARNT2	IDA		Human	PMID:24465693
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt2	IDA		Mouse	MGI:MGI:79449|PMID:8657146
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt2	IDA		Mouse	PMID:14701734
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Arnt2	IGI	MGI:MGI:98307	Mouse	PMID:14701734
Biological Process	GO:0006355	regulation of DNA-templated transcription	ARNT2	IDA		Human	PMID:11782478
Biological Process	GO:0006355	regulation of DNA-templated transcription	arnt2	IDA		Zfish	PMID:11072074|ZFIN:ZDB-PUB-001205-13
Biological Process	GO:0032355	response to estradiol	Arnt2	IEP		Rat	PMID:12859947|RGD:631760
Biological Process	GO:0001666	response to hypoxia	ARNT2	IDA		Human	PMID:12239177
Biological Process	GO:0001666	response to hypoxia	Arnt2	IEP		Rat	PMID:10873592|RGD:2301216
Biological Process	GO:0001666	response to hypoxia	arnt2	IDA		Zfish	PMID:11072074|ZFIN:ZDB-PUB-001205-13
Biological Process	GO:0007165	signal transduction	arnt2	IDA		Zfish	PMID:11072074|ZFIN:ZDB-PUB-001205-13
Biological Process	GO:0048798	swim bladder inflation	arnt2	IMP	ZFIN:ZDB-GENO-100415-7	Zfish	PMID:19374551
Biological Process	GO:0021591	ventricular system development	arnt2	IMP	ZFIN:ZDB-GENO-100415-7	Zfish	PMID:19374551

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern