Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARPC1B
  • Mouse genes Arpc1b
  • Rat genes Arpc1b
  • Zfish genes arpc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arpc1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	ARPC1B	IDA		Human	PMID:11741539
Molecular Function	GO:0005515	protein binding	ARPC1B	IPI	UniProtKB:Q5ZTM4	Human	PMID:25944859
Molecular Function	GO:0044877	protein-containing complex binding	Arpc1b	IPI	RGD:2382|RGD:1305848	Rat	PMID:18775315|RGD:11530062
Molecular Function	GO:0044877	protein-containing complex binding	Arpc1b	IPI	RGD:619839|RGD:1305848	Rat	PMID:18775315|RGD:11530062
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ARPC1B	IDA		Human	PMID:11741539
Cellular Component	GO:0005885	Arp2/3 protein complex	ARPC1B	IDA		Human	PMID:11741539
Cellular Component	GO:0070062	extracellular exosome	ARPC1B	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	ARPC1B	HDA		Human	PMID:21423176
Cellular Component	GO:0036284	tubulobulbar complex	Arpc1b	IDA		Rat	PMID:25637714|RGD:11046265
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	ARPC1B	IDA		Human	PMID:11741539
Biological Process	GO:0032355	response to estradiol	Arpc1b	IEP		Rat	PMID:19095743|RGD:11530058
Biological Process	GO:0043627	response to estrogen	Arpc1b	IEP		Rat	PMID:25637714|RGD:11046265
Biological Process	GO:0030217	T cell differentiation	arpc1b	IMP	ZFIN:ZDB-MRPHLNO-180510-5	Zfish	PMID:29127144
Biological Process	GO:0030217	T cell differentiation	arpc1b	IMP	ZFIN:ZDB-MRPHLNO-180510-6	Zfish	PMID:29127144
Biological Process	GO:0002574	thrombocyte differentiation	arpc1b	IMP	ZFIN:ZDB-MRPHLNO-180510-5	Zfish	PMID:29127144
Biological Process	GO:0002574	thrombocyte differentiation	arpc1b	IMP	ZFIN:ZDB-MRPHLNO-180510-6	Zfish	PMID:29127144

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern