Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARPC3
  • Mouse genes Arpc3
  • Rat genes Arpc3
  • Zfish genes arpc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arpc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	ARPC3	IDA		Human	PMID:11741539
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:P59998	Human	PMID:11162547
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:P59998	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:O00401	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:O43365	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:P48552	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:A2RTX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:O00401	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:O43365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:O95835-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:P14859-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:P46092	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:P59998	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q68J44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q8IZU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q8NC74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q9H609	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC3	IPI	UniProtKB:Q9NX95-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Arpc3	IPI	PR:Q9JLI7	Mouse	PMID:31146259
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ARPC3	IDA		Human	PMID:11741539
Cellular Component	GO:0005885	Arp2/3 protein complex	ARPC3	IDA		Human	PMID:11741539
Cellular Component	GO:0031252	cell leading edge	Arpc3	IDA		Rat	PMID:10209028|RGD:2306208
Cellular Component	GO:0070062	extracellular exosome	ARPC3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ARPC3	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ARPC3	HDA		Human	PMID:23533145
Cellular Component	GO:0031941	filamentous actin	Arpc3	IDA		Rat	PMID:10797548|RGD:11049163
Cellular Component	GO:0005925	focal adhesion	ARPC3	HDA		Human	PMID:21423176
Cellular Component	GO:0061850	growth cone leading edge	Arpc3	IDA		Rat	PMID:10797548|RGD:11049163
Cellular Component	GO:0030027	lamellipodium	ARPC3	IDA		Human	PMID:9230079
Cellular Component	GO:0030027	lamellipodium	Arpc3	IDA		Mouse	PMID:15294161
Cellular Component	GO:0016020	membrane	ARPC3	HDA		Human	PMID:19946888
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	ARPC3	IDA		Human	PMID:11741539
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Arpc3	IEP		Rat	PMID:10797548|RGD:11049163

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern