Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARPC4
  • Mouse genes Arpc4
  • Rat genes Arpc4
  • Zfish genes arpc4,arpc4l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arpc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	ARPC4	IDA		Human	PMID:11741539
Molecular Function	GO:0019899	enzyme binding	ARPC4	IPI	UniProtKB:Q8WXB1	Human	PMID:23921388
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:O15144	Human	PMID:11162547
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:O15145	Human	PMID:11162547
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:O15511	Human	PMID:11162547
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q9BPX5	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:O15145	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q9BPX5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q96PV4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q9BPX5	Human	PMID:26655834
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q9BPX5	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q96PV4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:O00401	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:O15145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q8WXB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q96PV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARPC4	IPI	UniProtKB:Q9BPX5	Human	PMID:32296183
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ARPC4	IPI	UniProtKB:O15143	Human	PMID:11162547
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ARPC4	IDA		Human	PMID:11741539
Cellular Component	GO:0005885	Arp2/3 protein complex	ARPC4	IDA		Human	PMID:11162547
Cellular Component	GO:0005885	Arp2/3 protein complex	ARPC4	IDA		Human	PMID:11741539
Cellular Component	GO:0070062	extracellular exosome	ARPC4	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ARPC4	HDA		Human	PMID:20458337
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	ARPC4	IDA		Human	PMID:11741539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern