Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARPIN,ARPIN-AP3S2
  • Mouse genes Arpin
  • Rat genes Arpin
  • Zfish genes arpin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arpin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ARPIN	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPIN	IPI	UniProtKB:Q9GZT8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARPIN	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Cellular Component	GO:0030027	lamellipodium	Arpin	IDA		Mouse	MGI:MGI:5521409|PMID:24132237
Biological Process	GO:0033058	directional locomotion	ARPIN	IMP		Human	PMID:24132237
Biological Process	GO:0033058	directional locomotion	arpin	IDA		Zfish	PMID:24132237|ZFIN:ZDB-PUB-170525-5
Biological Process	GO:0051126	negative regulation of actin nucleation	ARPIN	IDA		Human	PMID:24132237
Biological Process	GO:0030336	negative regulation of cell migration	ARPIN	IMP		Human	PMID:24132237
Biological Process	GO:0030336	negative regulation of cell migration	arpin	IMP		Zfish	PMID:24132237|ZFIN:ZDB-PUB-170525-5
Biological Process	GO:0030336	negative regulation of cell migration	arpin	IMP	ZFIN:ZDB-MRPHLNO-181030-3	Zfish	PMID:24132237
Biological Process	GO:2000393	negative regulation of lamellipodium morphogenesis	ARPIN	IMP		Human	PMID:24132237

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern