Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASB2
  • Mouse genes Asb2
  • Rat genes Asb2
  • Zfish genes asb2a.1,asb2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Asb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097602	cullin family protein binding	ASB2	IPI	UniProtKB:Q13616	Human	PMID:21119685
Molecular Function	GO:0097602	cullin family protein binding	ASB2	IPI	UniProtKB:Q93034	Human	PMID:21119685
Molecular Function	GO:0005515	protein binding	ASB2	IPI	UniProtKB:O60674	Human	PMID:21119685
Molecular Function	GO:0005515	protein binding	ASB2	IPI	UniProtKB:Q13309	Human	PMID:21119685
Molecular Function	GO:0005515	protein binding	ASB2	IPI	UniProtKB:Q15369	Human	PMID:21119685
Molecular Function	GO:0005515	protein binding	ASB2	IPI	UniProtKB:Q15370	Human	PMID:21119685
Molecular Function	GO:0005515	protein binding	Asb2	IPI	UniProtKB:P31001	Mouse	MGI:MGI:6102779|PMID:26343497
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ASB2	IDA		Human	PMID:16325183
Cellular Component	GO:0000151	ubiquitin ligase complex	ASB2	IDA		Human	PMID:16325183
Cellular Component	GO:0030018	Z disc	Asb2	IDA		Mouse	MGI:MGI:6102779|PMID:26343497
Biological Process	GO:0031532	actin cytoskeleton reorganization	Asb2	IMP		Mouse	MGI:MGI:6718235|PMID:29374072
Biological Process	GO:0055013	cardiac muscle cell development	Asb2	IMP		Mouse	MGI:MGI:6718235|PMID:29374072
Biological Process	GO:0055013	cardiac muscle cell development	asb2b	IMP	ZFIN:ZDB-GENO-171117-3	Zfish	PMID:28211472
Biological Process	GO:0055013	cardiac muscle cell development	asb2b	IGI	ZFIN:ZDB-GENE-051113-64	Zfish	PMID:28211472
Biological Process	GO:0055007	cardiac muscle cell differentiation	ASB2	IMP		Human	PMID:32179481
Biological Process	GO:0055003	cardiac myofibril assembly	asb2b	IGI	ZFIN:ZDB-GENE-051113-64	Zfish	PMID:28211472
Biological Process	GO:0055003	cardiac myofibril assembly	asb2b	IMP	ZFIN:ZDB-GENO-171117-3	Zfish	PMID:28211472
Biological Process	GO:0036336	dendritic cell migration	Asb2	IDA		Mouse	MGI:MGI:5510317|PMID:23632887
Biological Process	GO:0001947	heart looping	Asb2	IMP		Mouse	MGI:MGI:6717247|PMID:32179481
Biological Process	GO:0071800	podosome assembly	Asb2	IMP		Mouse	MGI:MGI:5510317|PMID:23632887
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ASB2	IMP		Human	PMID:21119685
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Asb2	IMP		Mouse	MGI:MGI:5510317|PMID:23632887
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Asb2	IMP		Mouse	MGI:MGI:6718235|PMID:29374072
Biological Process	GO:0016567	protein ubiquitination	ASB2	IDA		Human	PMID:16325183
Biological Process	GO:0014732	skeletal muscle atrophy	Asb2	IMP		Mouse	MGI:MGI:6716965|PMID:27182554
Biological Process	GO:0035914	skeletal muscle cell differentiation	Asb2	IMP		Mouse	PMID:22147266
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Asb2	IMP		Mouse	MGI:MGI:6102779|PMID:26343497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern