Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASCL1
  • Mouse genes Ascl1
  • Rat genes Ascl1
  • Zfish genes ascl1a,ascl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ascl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	ASCL1	IPI	UniProtKB:P15884	Human	PMID:10903890
Molecular Function	GO:0043425	bHLH transcription factor binding	ASCL1	IPI	UniProtKB:P15923	Human	PMID:11940670
Molecular Function	GO:0003682	chromatin binding	Ascl1	IDA		Mouse	PMID:23639443
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ASCL1	IDA		Human	PMID:10903890
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Ascl1	IDA		Mouse	PMID:17141158
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ascl1a	IPI	ZFIN:ZDB-GENE-040426-780	Zfish	PMID:30606747
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ASCL1	IDA		Human	PMID:11736660
Molecular Function	GO:0003690	double-stranded DNA binding	Ascl1	IDA		Rat	PMID:9521744|RGD:2314148
Molecular Function	GO:0070888	E-box binding	ASCL1	IDA		Human	PMID:10903890
Molecular Function	GO:0070888	E-box binding	ASCL1	IDA		Human	PMID:11736660
Molecular Function	GO:0042802	identical protein binding	Ascl1	IPI	RGD:71010	Rat	PMID:9521744|RGD:2314148
Molecular Function	GO:0003676	nucleic acid binding	ASCL1	EXP		Human	PMID:28402879
Molecular Function	GO:0005515	protein binding	ASCL1	IPI	UniProtKB:P15884	Human	PMID:10903890
Molecular Function	GO:0005515	protein binding	ASCL1	IPI	UniProtKB:P15923	Human	PMID:10903890
Molecular Function	GO:0005515	protein binding	ASCL1	IPI	UniProtKB:A0A024R8A9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASCL1	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASCL1	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ascl1	IPI	PR:E9PZZ1	Mouse	PMID:23639443
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ASCL1	IDA		Human	PMID:11736660
Molecular Function	GO:0043565	sequence-specific DNA binding	Ascl1	IDA		Mouse	PMID:17141158
Molecular Function	GO:0043565	sequence-specific DNA binding	ascl1a	IPI	ZFIN:ZDB-GENE-040426-1810	Zfish	PMID:23000964
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ASCL1	IDA		Human	PMID:28473536
Cellular Component	GO:0043025	neuronal cell body	Ascl1	IDA		Mouse	PMID:15065125
Cellular Component	GO:0043025	neuronal cell body	Ascl1	IDA		Mouse	PMID:11133151
Cellular Component	GO:0005634	nucleus	ASCL1	IDA		Human	PMID:12858003
Cellular Component	GO:0005634	nucleus	ASCL1	IDA		Human	PMID:17507989
Cellular Component	GO:0005634	nucleus	ASCL1	IDA		Human	PMID:18311112
Cellular Component	GO:0005634	nucleus	Ascl1	IDA		Mouse	PMID:12397111
Cellular Component	GO:0005634	nucleus	Ascl1	IDA		Mouse	PMID:10952889
Cellular Component	GO:0005634	nucleus	Ascl1	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Ascl1	IDA		Mouse	PMID:1576967
Biological Process	GO:0021984	adenohypophysis development	ascl1a	IMP		Zfish	PMID:16481349|ZFIN:ZDB-PUB-060227-5
Biological Process	GO:0021984	adenohypophysis development	ascl1a	IMP	ZFIN:ZDB-GENO-040716-9	Zfish	PMID:16481349
Biological Process	GO:0061104	adrenal chromaffin cell differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:12361965
Biological Process	GO:0031103	axon regeneration	ascl1a	IMP	ZFIN:ZDB-MRPHLNO-050301-4	Zfish	PMID:25751153
Biological Process	GO:0007420	brain development	ascl1b	IEP		Zfish	PMID:12524185
Biological Process	GO:0061103	carotid body glomus cell differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:15878769
Biological Process	GO:0043697	cell dedifferentiation	ascl1a	IGI	ZFIN:ZDB-GENE-040426-1810,ZFIN:ZDB-GENE-990708-5	Zfish	PMID:23000964
Biological Process	GO:0048469	cell maturation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16766700
Biological Process	GO:0071259	cellular response to magnetism	Ascl1	IEP		Rat	PMID:19382241|RGD:2311599
Biological Process	GO:0021954	central nervous system neuron development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16469766
Biological Process	GO:0021954	central nervous system neuron development	Ascl1	IGI	MGI:MGI:109619	Mouse	PMID:15169849
Biological Process	GO:0021987	cerebral cortex development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:17678855
Biological Process	GO:0021892	cerebral cortex GABAergic interneuron differentiation	ASCL1	IEP		Human	PMID:12050665
Biological Process	GO:0043009	chordate embryonic development	ascl1b	IEP		Zfish	PMID:12524185
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:22991444
Biological Process	GO:0048566	embryonic digestive tract development	ascl1a	IMP	ZFIN:ZDB-GENO-120824-4	Zfish	PMID:23352790
Biological Process	GO:0031018	endocrine pancreas development	ascl1b	IMP	ZFIN:ZDB-MRPHLNO-050308-14,ZFIN:ZDB-MRPHLNO-140811-4	Zfish	PMID:23835295
Biological Process	GO:0031018	endocrine pancreas development	ascl1b	IMP	ZFIN:ZDB-MRPHLNO-050308-14	Zfish	PMID:23835295
Biological Process	GO:0002070	epithelial cell maturation	ascl1a	IMP	ZFIN:ZDB-GENO-040716-9	Zfish	PMID:16481349
Biological Process	GO:0021879	forebrain neuron differentiation	Ascl1	IDA		Rat	PMID:17936272|RGD:2314144
Biological Process	GO:0097154	GABAergic neuron differentiation	Ascl1	IGI	MGI:MGI:3040955	Mouse	PMID:15071116
Biological Process	GO:0048699	generation of neurons	Ascl1	IMP	MGI:MGI:3639318	Mouse	PMID:23616538
Biological Process	GO:0007507	heart development	Ascl1	IEP		Rat	PMID:11803116|RGD:704410
Biological Process	GO:0021575	hindbrain morphogenesis	ascl1a	IGI	ZFIN:ZDB-GENE-980526-174	Zfish	PMID:15659486|ZFIN:ZDB-PUB-050125-4
Biological Process	GO:0021575	hindbrain morphogenesis	ascl1b	IGI	ZFIN:ZDB-GENE-990415-174	Zfish	PMID:15659486|ZFIN:ZDB-PUB-050125-4
Biological Process	GO:0021575	hindbrain morphogenesis	ascl1b	IGI	ZFIN:ZDB-GENE-980526-90	Zfish	PMID:15659486|ZFIN:ZDB-PUB-050125-4
Biological Process	GO:0021575	hindbrain morphogenesis	ascl1a	IMP		Zfish	PMID:15659486|ZFIN:ZDB-PUB-050125-4
Biological Process	GO:0021575	hindbrain morphogenesis	ascl1b	IMP		Zfish	PMID:15659486|ZFIN:ZDB-PUB-050125-4
Biological Process	GO:0060575	intestinal epithelial cell differentiation	ascl1a	IMP	ZFIN:ZDB-GENO-120824-4	Zfish	PMID:23353550
Biological Process	GO:0061100	lung neuroendocrine cell differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:9126746
Biological Process	GO:0097475	motor neuron migration	Ascl1	IGI	MGI:MGI:108055	Mouse	PMID:15976074
Biological Process	GO:0097475	motor neuron migration	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:15976074
Biological Process	GO:0050883	musculoskeletal movement, spinal reflex action	Ascl1	IMP	MGI:MGI:3639318	Mouse	PMID:23616538
Biological Process	GO:0043066	negative regulation of apoptotic process	ASCL1	IMP		Human	PMID:17507989
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ASCL1	IDA		Human	PMID:11736660
Biological Process	GO:0010629	negative regulation of gene expression	ascl1a	IMP	ZFIN:ZDB-MRPHLNO-050301-3	Zfish	PMID:21911394
Biological Process	GO:0010629	negative regulation of gene expression	ascl1a	IMP	ZFIN:ZDB-MRPHLNO-050301-4	Zfish	PMID:21911394
Biological Process	GO:0045665	negative regulation of neuron differentiation	ASCL1	IDA		Human	PMID:12000752
Biological Process	GO:0045665	negative regulation of neuron differentiation	Ascl1	IDA		Rat	PMID:17936272|RGD:2314144
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ASCL1	IDA		Human	PMID:11736660
Biological Process	GO:0007399	nervous system development	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0007399	nervous system development	Ascl1	IDA		Rat	PMID:11923194|RGD:727258
Biological Process	GO:0007399	nervous system development	ascl1a	IMP		Zfish	PMID:12702659
Biological Process	GO:0007399	nervous system development	ascl1a	IGI	ZFIN:ZDB-GENE-990415-174	Zfish	PMID:12702659
Biological Process	GO:0061351	neural precursor cell proliferation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:21536733
Biological Process	GO:0007400	neuroblast fate determination	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:11032813
Biological Process	GO:0007400	neuroblast fate determination	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:12397111
Biological Process	GO:0007405	neuroblast proliferation	Ascl1	IGI	MGI:MGI:108055	Mouse	PMID:15976074
Biological Process	GO:0061101	neuroendocrine cell differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:10952889
Biological Process	GO:0022008	neurogenesis	ASCL1	IDA		Human	PMID:19008346
Biological Process	GO:0048666	neuron development	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048666	neuron development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:9108377
Biological Process	GO:0030182	neuron differentiation	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0030182	neuron differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16469766
Biological Process	GO:0030182	neuron differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:15133515
Biological Process	GO:0030182	neuron differentiation	Ascl1	IDA		Mouse	PMID:18184563
Biological Process	GO:0048663	neuron fate commitment	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048663	neuron fate commitment	Ascl1	IGI	MGI:MGI:2151057	Mouse	PMID:16020526
Biological Process	GO:0048663	neuron fate commitment	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16715081
Biological Process	GO:0048663	neuron fate commitment	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:19191219
Biological Process	GO:0048663	neuron fate commitment	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:12629181
Biological Process	GO:0048665	neuron fate specification	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048665	neuron fate specification	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16469766
Biological Process	GO:0003358	noradrenergic neuron development	Ascl1	IMP		Mouse	MGI:MGI:3772428|PMID:18094025
Biological Process	GO:0003359	noradrenergic neuron fate commitment	ASCL1	IMP		Human	PMID:14532329
Biological Process	GO:0007219	Notch signaling pathway	ASCL1	IDA		Human	PMID:16160079
Biological Process	GO:0007219	Notch signaling pathway	Ascl1	IGI	MGI:MGI:108055	Mouse	PMID:15976074
Biological Process	GO:0007219	Notch signaling pathway	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:11073877
Biological Process	GO:0060166	olfactory pit development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:9108377
Biological Process	GO:0021779	oligodendrocyte cell fate commitment	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:17678855
Biological Process	GO:0014003	oligodendrocyte development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:18287202
Biological Process	GO:0048709	oligodendrocyte differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:18287202
Biological Process	GO:0048709	oligodendrocyte differentiation	Ascl1	IGI	MGI:MGI:108055	Mouse	PMID:15976074
Biological Process	GO:0007389	pattern specification process	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:15930101
Biological Process	GO:0048935	peripheral nervous system neuron development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:8845150
Biological Process	GO:0045787	positive regulation of cell cycle	Ascl1	IDA		Mouse	PMID:21536733
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ascl1a	IDA		Zfish	PMID:23000964
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:21536733
Biological Process	GO:0050769	positive regulation of neurogenesis	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16469766
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16469766
Biological Process	GO:0045666	positive regulation of neuron differentiation	Ascl1	IDA		Rat	PMID:10648228|RGD:13673741
Biological Process	GO:0045666	positive regulation of neuron differentiation	Ascl1	IDA		Rat	PMID:17936272|RGD:2314144
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:11073877
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ASCL1	IDA		Human	PMID:10903890
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:99532	Mouse	PMID:8900141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:99458	Mouse	PMID:8900141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:101895	Mouse	PMID:17141158
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:99533	Mouse	PMID:8900141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IDA		Mouse	PMID:23434913
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IDA		Mouse	PMID:17141158
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:102564	Mouse	PMID:17141158
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:98510	Mouse	PMID:8900141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ascl1	IGI	MGI:MGI:2448528	Mouse	PMID:23639443
Biological Process	GO:0031099	regeneration	ascl1a	IMP	ZFIN:ZDB-MRPHLNO-050301-3	Zfish	PMID:20935637
Biological Process	GO:0031099	regeneration	ascl1a	IGI	ZFIN:ZDB-MRPHLNO-050301-3,ZFIN:ZDB-MRPHLNO-110913-1	Zfish	PMID:20935637
Biological Process	GO:0042127	regulation of cell population proliferation	Ascl1	IDA		Mouse	PMID:19793887
Biological Process	GO:0030856	regulation of epithelial cell differentiation	Ascl1	IMP	MGI:MGI:3639318	Mouse	PMID:23284756
Biological Process	GO:0010468	regulation of gene expression	Ascl1	IMP		Mouse	MGI:MGI:3772428|PMID:18094025
Biological Process	GO:0010468	regulation of gene expression	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:18287202
Biological Process	GO:0010468	regulation of gene expression	Ascl1	IMP	MGI:MGI:2388165	Mouse	PMID:16469766
Biological Process	GO:0010468	regulation of gene expression	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16469766
Biological Process	GO:0007346	regulation of mitotic cell cycle	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:22991444
Biological Process	GO:0050767	regulation of neurogenesis	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:20144606
Biological Process	GO:0050767	regulation of neurogenesis	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:22991444
Biological Process	GO:0008593	regulation of Notch signaling pathway	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:19191219
Biological Process	GO:0060165	regulation of timing of subpallium neuron differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:9876181
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ascl1	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ascl1	IDA		Mouse	PMID:19796622
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ascl1a	IMP		Zfish	PMID:30606747
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ascl1a	IDA		Zfish	PMID:30606747
Biological Process	GO:0070849	response to epidermal growth factor	Ascl1	IEP		Rat	PMID:9473334|RGD:2314149
Biological Process	GO:0051593	response to folic acid	Ascl1	IEP		Rat	PMID:19001765|RGD:2314143
Biological Process	GO:0010226	response to lithium ion	Ascl1	IEP		Rat	PMID:17263970|RGD:2314145
Biological Process	GO:0032526	response to retinoic acid	ASCL1	IEP		Human	PMID:12000752
Biological Process	GO:0032526	response to retinoic acid	Ascl1	IEP		Rat	PMID:11803116|RGD:704410
Biological Process	GO:0070654	sensory epithelium regeneration	ascl1a	IGI	ZFIN:ZDB-GENE-040426-1810,ZFIN:ZDB-GENE-990708-5	Zfish	PMID:23000964
Biological Process	GO:0070654	sensory epithelium regeneration	ascl1a	IEP		Zfish	PMID:21911394
Biological Process	GO:0021527	spinal cord association neuron differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:16715081
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	Ascl1	IGI	MGI:MGI:97347	Mouse	PMID:18287202
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	Ascl1	IGI	MGI:MGI:1355331	Mouse	PMID:18287202
Biological Process	GO:0021530	spinal cord oligodendrocyte cell fate specification	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:18287202
Biological Process	GO:0061102	stomach neuroendocrine cell differentiation	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:18173746
Biological Process	GO:0060163	subpallium neuron fate commitment	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:9876181
Biological Process	GO:0061549	sympathetic ganglion development	Ascl1	IMP		Mouse	MGI:MGI:3772428|PMID:18094025
Biological Process	GO:0061549	sympathetic ganglion development	ascl1a	IGI	ZFIN:ZDB-MRPHLNO-050308-13,ZFIN:ZDB-MRPHLNO-130820-9	Zfish	PMID:23754957
Biological Process	GO:0061549	sympathetic ganglion development	ascl1a	IMP	ZFIN:ZDB-MRPHLNO-050308-13	Zfish	PMID:23754957
Biological Process	GO:0061195	taste bud formation	ascl1a	IMP	ZFIN:ZDB-GENO-120824-4	Zfish	PMID:21791527
Biological Process	GO:0042246	tissue regeneration	ascl1a	IDA		Zfish	PMID:30606747
Biological Process	GO:0042246	tissue regeneration	ascl1a	IMP		Zfish	PMID:30606747
Biological Process	GO:0060579	ventral spinal cord interneuron fate commitment	Ascl1	IMP		Mouse	MGI:MGI:3587461|PMID:16020526
Biological Process	GO:0021750	vestibular nucleus development	Ascl1	IMP	MGI:MGI:1857470	Mouse	PMID:12885554

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern