Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASH1L
  • Mouse genes Ash1l
  • Rat genes Ash1l
  • Zfish genes ash1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ash1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ASH1L	IDA		Human	PMID:26002201
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	Ash1l	IDA		Mouse	PMID:24012418
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ash1l	IDA		Mouse	MGI:MGI:6274969|PMID:22939622
Cellular Component	GO:0005794	Golgi apparatus	ASH1L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ASH1L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ASH1L	IDA		Human	PMID:25593309
Biological Process	GO:0046697	decidualization	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0030317	flagellated sperm motility	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0097676	histone H3-K36 dimethylation	ASH1L	IDA		Human	PMID:26002201
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Ash1l	IMP		Mouse	PMID:24012418
Biological Process	GO:0006954	inflammatory response	Ash1l	IGI	MGI:MGI:2156367	Mouse	PMID:24012418
Biological Process	GO:0006954	inflammatory response	Ash1l	IGI	MGI:MGI:96824	Mouse	PMID:24012418
Biological Process	GO:0032635	interleukin-6 production	Ash1l	IGI	MGI:MGI:2156367	Mouse	PMID:24012418
Biological Process	GO:0032635	interleukin-6 production	Ash1l	IGI	MGI:MGI:96824	Mouse	PMID:24012418
Biological Process	GO:0010934	macrophage cytokine production	Ash1l	IGI	MGI:MGI:2156367	Mouse	PMID:24012418
Biological Process	GO:0010934	macrophage cytokine production	Ash1l	IGI	MGI:MGI:96824	Mouse	PMID:24012418
Biological Process	GO:0000165	MAPK cascade	Ash1l	IMP		Mouse	PMID:24012418
Biological Process	GO:0002674	negative regulation of acute inflammatory response	Ash1l	IMP	MGI:MGI:5563008	Mouse	PMID:24012418
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	Ash1l	IMP		Mouse	PMID:24012418
Biological Process	GO:0050728	negative regulation of inflammatory response	Ash1l	IGI	MGI:MGI:96824	Mouse	PMID:24012418
Biological Process	GO:0050728	negative regulation of inflammatory response	Ash1l	IGI	MGI:MGI:2156367	Mouse	PMID:24012418
Biological Process	GO:0043409	negative regulation of MAPK cascade	Ash1l	IMP		Mouse	PMID:24012418
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ash1l	IDA		Mouse	PMID:24012418
Biological Process	GO:0009791	post-embryonic development	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0010468	regulation of gene expression	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0048733	sebaceous gland development	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0007338	single fertilization	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0001501	skeletal system development	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:1903699	tarsal gland development	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0006366	transcription by RNA polymerase II	Ash1l	IDA		Mouse	PMID:24012418
Biological Process	GO:1903709	uterine gland development	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994
Biological Process	GO:0061038	uterus morphogenesis	Ash1l	IMP	MGI:MGI:3852878	Mouse	PMID:26333994

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern