Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASH2L
  • Mouse genes Ash2l
  • Rat genes Ash2l
  • Zfish genes ash2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ash2l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	ASH2L	IPI	UniProtKB:Q02248	Human	PMID:22723415
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:12482968
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:12482968
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P51610	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:O00255	Human	PMID:14992727
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:16603732
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:16892064
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q6ZW49	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q6ZW49	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q6ZW49	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:O15047	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9UPS6	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:19047629
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:19131338
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q03164	Human	PMID:19187761
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P04637	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:19556245
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:19556245
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9HCK8	Human	PMID:20085832
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:21220120
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P10275	Human	PMID:22722839
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P04637	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P51610	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q09472	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:O43823	Human	PMID:23995757
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:23995757
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P51610	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14686	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q6ZW49	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:25456412
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P24863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q14696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q15291	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q9C005	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:O75460-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P54652	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:Q0VDC6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ASH2L	IPI	UniProtKB:P10275	Human	PMID:33640491
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q91ZK0	Mouse	MGI:MGI:6093238|PMID:18495928
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q8BX09	Mouse	MGI:MGI:4949547|PMID:21448134
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q8BX09	Mouse	MGI:MGI:5927213|PMID:26320581
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q8BX09	Mouse	MGI:MGI:5315331|PMID:21335234
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q8BX09	Mouse	MGI:MGI:3718866|PMID:17500065
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q8BX09	Mouse	MGI:MGI:5285127|PMID:21477851
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	UniProtKB:Q8BX09	Mouse	MGI:MGI:3773768|PMID:17825402
Molecular Function	GO:0005515	protein binding	Ash2l	IPI	PR:P70323	Mouse	PMID:20463296
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ASH2L	IDA		Human	PMID:16603732
Cellular Component	GO:0000791	euchromatin	Ash2l	IDA		Mouse	MGI:MGI:5428344|PMID:22723415
Cellular Component	GO:0035097	histone methyltransferase complex	ASH2L	IDA		Human	PMID:17355966
Cellular Component	GO:0035097	histone methyltransferase complex	ASH2L	IDA		Human	PMID:17500065
Cellular Component	GO:0035097	histone methyltransferase complex	ASH2L	IDA		Human	PMID:19556245
Cellular Component	GO:0071339	MLL1 complex	ASH2L	IPI		Human	PMID:23508102
Cellular Component	GO:0071339	MLL1 complex	Ash2l	IDA		Mouse	MGI:MGI:4419079|PMID:15960975
Cellular Component	GO:0044665	MLL1/2 complex	ASH2L	IPI		Human	PMID:23508102
Cellular Component	GO:0044666	MLL3/4 complex	ASH2L	IPI		Human	PMID:23508102
Cellular Component	GO:0044666	MLL3/4 complex	ASH2L	IDA		Human	PMID:17500065
Cellular Component	GO:0005634	nucleus	ASH2L	IDA		Human	PMID:15199122
Cellular Component	GO:0005634	nucleus	ASH2L	IDA		Human	PMID:17500065
Cellular Component	GO:0005634	nucleus	ASH2L	IDA		Human	PMID:18245475
Cellular Component	GO:0005634	nucleus	ASH2L	IMP		Human	PMID:22723415
Cellular Component	GO:0048188	Set1C/COMPASS complex	ASH2L	IPI		Human	PMID:23508102
Cellular Component	GO:0048188	Set1C/COMPASS complex	ASH2L	IDA		Human	PMID:17998332
Cellular Component	GO:0048188	Set1C/COMPASS complex	ASH2L	IDA		Human	PMID:18838538
Biological Process	GO:0006974	DNA damage response	ASH2L	IDA		Human	PMID:17500065
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	ash2l	IMP		Zfish	PMID:24240475
Biological Process	GO:0008284	positive regulation of cell population proliferation	ASH2L	IMP		Human	PMID:18245475
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ash2l	IGI	MGI:MGI:98493	Mouse	PMID:20463296
Biological Process	GO:0060319	primitive erythrocyte differentiation	ash2l	IMP		Zfish	PMID:24240475
Biological Process	GO:0043627	response to estrogen	ASH2L	IDA		Human	PMID:16603732
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ASH2L	IDA		Human	PMID:19556245

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern