Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASPH
  • Mouse genes Asph
  • Rat genes Asph
  • Zfish genes unm_hu7910
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Asph

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ASPH	IPI	UniProtKB:Q13586-8	Human	PMID:22586105
Molecular Function	GO:0005515	protein binding	ASPH	IPI	UniProtKB:Q96D31-8	Human	PMID:22586105
Molecular Function	GO:0005515	protein binding	ASPH	IPI	UniProtKB:O43681	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Asph	IPI	UniProtKB:O14958	Mouse	MGI:MGI:5427341|PMID:22123818
Cellular Component	GO:0032541	cortical endoplasmic reticulum	ASPH	IDA		Human	PMID:21062895
Cellular Component	GO:0005737	cytoplasm	Asph	IDA		Mouse	MGI:MGI:5427341|PMID:22123818
Cellular Component	GO:0005783	endoplasmic reticulum	ASPH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ASPH	IDA		Human	PMID:21062895
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	ASPH	IDA		Human	PMID:18387192
Biological Process	GO:0008283	cell population proliferation	Asph	IGI	MGI:MGI:88039	Mouse	PMID:11773073
Biological Process	GO:0060325	face morphogenesis	Asph	IMP	MGI:MGI:2179287	Mouse	PMID:11773073
Biological Process	GO:0035108	limb morphogenesis	Asph	IMP	MGI:MGI:2179287	Mouse	PMID:11773073
Biological Process	GO:0008285	negative regulation of cell population proliferation	Asph	IGI	MGI:MGI:88039	Mouse	PMID:11773073
Biological Process	GO:0007389	pattern specification process	Asph	IMP	MGI:MGI:2179287	Mouse	PMID:11773073
Biological Process	GO:0042264	peptidyl-aspartic acid hydroxylation	Asph	IDA		Mouse	PMID:11773073
Biological Process	GO:0045862	positive regulation of proteolysis	ASPH	IDA		Human	PMID:18387192
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Asph	IMP		Rat	PMID:17150191|RGD:2325826
Biological Process	GO:1901879	regulation of protein depolymerization	Asph	IDA		Mouse	MGI:MGI:5427341|PMID:22123818
Biological Process	GO:0031647	regulation of protein stability	Asph	IDA		Mouse	MGI:MGI:5427341|PMID:22123818
Biological Process	GO:0060021	roof of mouth development	Asph	IMP	MGI:MGI:2179287	Mouse	PMID:11773073

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern