Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASPM
  • Mouse genes Aspm
  • Rat genes Aspm
  • Zfish genes aspm
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aspm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	Aspm	IDA		Mouse	PMID:23152892
Cellular Component	GO:0016324	apical plasma membrane	Aspm	IDA		Rat	PMID:17534152|RGD:13442487
Cellular Component	GO:0005813	centrosome	Aspm	IDA		Rat	PMID:17534152|RGD:13442487
Cellular Component	GO:0005737	cytoplasm	Aspm	IDA		Mouse	PMID:23152892
Cellular Component	GO:0072687	meiotic spindle	Aspm	IDA		Mouse	PMID:23152892
Cellular Component	GO:0005874	microtubule	Aspm	IDA		Mouse	PMID:23152892
Cellular Component	GO:0036449	microtubule minus-end	ASPM	IDA		Human	PMID:21044324
Cellular Component	GO:0030496	midbody	Aspm	IDA		Mouse	PMID:20823249
Cellular Component	GO:0030496	midbody	Aspm	IDA		Rat	PMID:17534152|RGD:13442487
Cellular Component	GO:0097431	mitotic spindle pole	ASPM	IDA		Human	PMID:15972725
Cellular Component	GO:0097431	mitotic spindle pole	ASPM	IDA		Human	PMID:21044324
Cellular Component	GO:0097431	mitotic spindle pole	Aspm	IDA		Mouse	PMID:23152892
Cellular Component	GO:0097431	mitotic spindle pole	Aspm	IDA		Mouse	PMID:22031545
Cellular Component	GO:0097431	mitotic spindle pole	Aspm	IDA		Rat	PMID:17534152|RGD:13442487
Cellular Component	GO:0005634	nucleus	ASPM	IDA		Human	PMID:21044324
Cellular Component	GO:0000922	spindle pole	Aspm	IDA		Mouse	PMID:20823249
Cellular Component	GO:0000922	spindle pole	Aspm	IDA		Mouse	PMID:16798874
Biological Process	GO:0008356	asymmetric cell division	Aspm	IMP		Mouse	PMID:16798874
Biological Process	GO:0007420	brain development	Aspm	IMP		Mouse	PMID:20823249
Biological Process	GO:0021987	cerebral cortex development	Aspm	IMP	MGI:MGI:5573152	Mouse	PMID:24220505
Biological Process	GO:0048589	developmental growth	Aspm	IMP		Mouse	PMID:20823249
Biological Process	GO:0021873	forebrain neuroblast division	Aspm	IMP		Mouse	PMID:16798874
Biological Process	GO:0051661	maintenance of centrosome location	Aspm	IMP		Mouse	PMID:16798874
Biological Process	GO:0008584	male gonad development	Aspm	IMP	MGI:MGI:5573152	Mouse	PMID:24220505
Biological Process	GO:0090306	meiotic spindle assembly	Aspm	IMP		Mouse	PMID:23152892
Biological Process	GO:0000278	mitotic cell cycle	aspm	IMP	ZFIN:ZDB-MRPHLNO-110805-1	Zfish	PMID:21620798
Biological Process	GO:0045769	negative regulation of asymmetric cell division	Aspm	IMP		Mouse	PMID:16798874
Biological Process	GO:0045665	negative regulation of neuron differentiation	Aspm	IMP		Mouse	PMID:16798874
Biological Process	GO:0007405	neuroblast proliferation	Aspm	IMP		Mouse	PMID:21937711
Biological Process	GO:0007405	neuroblast proliferation	Aspm	IGI	MGI:MGI:88276	Mouse	PMID:21937711
Biological Process	GO:0001764	neuron migration	Aspm	IGI	MGI:MGI:88276	Mouse	PMID:21937711
Biological Process	GO:0001764	neuron migration	Aspm	IMP		Mouse	PMID:21937711
Biological Process	GO:0097150	neuronal stem cell population maintenance	Aspm	IMP		Mouse	PMID:19896444
Biological Process	GO:0048477	oogenesis	Aspm	IMP	MGI:MGI:4345319	Mouse	PMID:20823249
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Aspm	IGI	MGI:MGI:88276	Mouse	PMID:21937711
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Aspm	IMP		Mouse	PMID:21937711
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Aspm	IGI	MGI:MGI:88276	Mouse	PMID:21937711
Biological Process	GO:0051445	regulation of meiotic cell cycle	Aspm	IMP		Mouse	MGI:MGI:5573217|PMID:23152892
Biological Process	GO:0007283	spermatogenesis	Aspm	IMP	MGI:MGI:4345319	Mouse	PMID:20823249
Biological Process	GO:0051653	spindle localization	ASPM	IMP		Human	PMID:21044324
Biological Process	GO:0007051	spindle organization	ASPM	IMP		Human	PMID:21044324

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern