Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ASPN
  • Mouse genes Aspn
  • Rat genes Aspn
  • Zfish genes aspn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aspn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	ASPN	IDA		Human	PMID:19589127
Molecular Function	GO:0005515	protein binding	Aspn	IPI	UniProtKB:P01137|UniProtKB:P10600|UniProtKB:P61812	Mouse	MGI:MGI:3762064|PMID:17827158
Molecular Function	GO:0005515	protein binding	Aspn	IPI	UniProtKB:P21274	Mouse	MGI:MGI:3722035|PMID:17522060
Cellular Component	GO:0042995	cell projection	Aspn	IDA		Rat	PMID:24967458|RGD:9684959
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ASPN	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ASPN	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ASPN	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ASPN	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ASPN	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Aspn	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Aspn	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0031012	extracellular matrix	ASPN	IDA		Human	PMID:17827158
Cellular Component	GO:0031012	extracellular matrix	Aspn	IDA		Mouse	PMID:11152692
Biological Process	GO:0030282	bone mineralization	ASPN	IDA		Human	PMID:19589127
Biological Process	GO:0070171	negative regulation of tooth mineralization	Aspn	IDA		Mouse	MGI:MGI:3722035|PMID:17522060
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ASPN	IDA		Human	PMID:17827158
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Aspn	IDA		Mouse	MGI:MGI:3762064|PMID:17827158
Biological Process	GO:1902617	response to fluoride	Aspn	IEP		Rat	PMID:24967458|RGD:9684959

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern